7MWS
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![BU of 7mws by Molmil](/molmil-images/mine/7mws) | Crystal structure of tamarin CD81 large extracellular loop | 分子名称: | CD81 protein, GLYCEROL, TETRAETHYLENE GLYCOL | 著者 | Kumar, A, Hossain, R.A, Yost, S.A, Bu, W, Wang, Y, Dearborn, A.D, Grakoui, A, Cohen, J.I, Marcotrigiano, J. | 登録日 | 2021-05-17 | 公開日 | 2021-09-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into hepatitis C virus receptor binding and entry. Nature, 598, 2021
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7JK9
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![BU of 7jk9 by Molmil](/molmil-images/mine/7jk9) | Helical filaments of plant light-dependent protochlorophyllide oxidoreductase (LPOR) bound to NADPH, Pchlide, and membrane | 分子名称: | 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Protochlorophyllide, ... | 著者 | Nguyen, H.C, Gabruk, M, Frost, A. | 登録日 | 2020-07-28 | 公開日 | 2021-03-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Photocatalytic LPOR forms helical lattices that shape membranes for chlorophyll synthesis. Nat.Plants, 7, 2021
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7MPU
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3KF2
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7JKQ
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![BU of 7jkq by Molmil](/molmil-images/mine/7jkq) | Human DPP9-CARD8 complex | 分子名称: | Caspase recruitment domain-containing protein 8, Dipeptidyl peptidase 9 | 著者 | Sharif, H, Hollingsworth, L.R. | 登録日 | 2020-07-28 | 公開日 | 2021-05-26 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment. Immunity, 54, 2021
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7JKS
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![BU of 7jks by Molmil](/molmil-images/mine/7jks) | Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2411a in complex with HIV-1 gp120 core | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 core, The heavy chain of antibody 2411a, ... | 著者 | Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R. | 登録日 | 2020-07-28 | 公開日 | 2021-06-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth. Immunity, 54, 2021
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3KH9
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![BU of 3kh9 by Molmil](/molmil-images/mine/3kh9) | Crystal structure of the periplasmic soluble domain of oxidized CcmG from Pseudomonas aeruginosa | 分子名称: | Thiol:disulfide interchange protein dsbE | 著者 | Di Matteo, A, Calosci, N, Gianni, S, Jemth, P, Brunori, M, Travaglini Allocatelli, C. | 登録日 | 2009-10-30 | 公開日 | 2010-04-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus. Proteins, 78, 2010
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3KHC
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3KHU
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![BU of 3khu by Molmil](/molmil-images/mine/3khu) | Crystal structure of human UDP-glucose dehydrogenase Glu161Gln, in complex with thiohemiacetal intermediate | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, UDP-glucose 6-dehydrogenase, ... | 著者 | Chaikuad, A, Egger, S, Yue, W.W, Guo, K, Sethi, R, Filippakopoulos, P, Muniz, J.R.C, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Kavanagh, K.L, Nidetzky, B, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2009-10-30 | 公開日 | 2009-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Kinetic Evidence That Catalytic Reaction of Human UDP-glucose 6-Dehydrogenase Involves Covalent Thiohemiacetal and Thioester Enzyme Intermediates. J.Biol.Chem., 287, 2012
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3KJG
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![BU of 3kjg by Molmil](/molmil-images/mine/3kjg) | ADP-bound state of CooC1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | 著者 | Jeoung, J.-H, Dobbek, H. | 登録日 | 2009-11-03 | 公開日 | 2010-01-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases J.Mol.Biol., 396, 2010
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7MQJ
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![BU of 7mqj by Molmil](/molmil-images/mine/7mqj) | Dhr1 Helicase Core | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable ATP-dependent RNA helicase DHR1 | 著者 | Miller, L, Chaker-Margot, M, Klinge, S. | 登録日 | 2021-05-05 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
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3KIE
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2H0S
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7MJ1
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![BU of 7mj1 by Molmil](/molmil-images/mine/7mj1) | LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with NAD | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P. | 登録日 | 2021-04-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.402 Å) | 主引用文献 | The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 118, 2021
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2GYI
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![BU of 2gyi by Molmil](/molmil-images/mine/2gyi) | DESIGN, SYNTHESIS, AND CHARACTERIZATION OF A POTENT XYLOSE ISOMERASE INHIBITOR, D-THREONOHYDROXAMIC ACID, AND HIGH-RESOLUTION X-RAY CRYSTALLOGRAPHIC STRUCTURE OF THE ENZYME-INHIBITOR COMPLEX | 分子名称: | 2,3,4,N-TETRAHYDROXY-BUTYRIMIDIC ACID, MAGNESIUM ION, XYLOSE ISOMERASE | 著者 | Allen, K.N, Lavie, A, Petsko, G.A, Ringe, D. | 登録日 | 1994-09-01 | 公開日 | 1995-07-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Design, Synthesis, and Characterization of a Potent Xylose Isomerase Inhibitor, D-Threonohydroxamic Acid, and High-Resolution X-Ray Crystallographic Structure of the Enzyme-Inhibitor Complex Biochemistry, 34, 1995
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2OQI
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![BU of 2oqi by Molmil](/molmil-images/mine/2oqi) | Human Dipeptidyl Peptidase IV (DPP4) with Piperidinone-constrained phenethylamine | 分子名称: | (4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) | 著者 | Pei, Z, Li, X, von Geldern, T.W, Longenecker, K.L, Pireh, D, Stewart, K.D, Backes, B.J, Lai, C, Lubben, T.H, Ballaron, S.J, Beno, D.W, Kempf-Grote, A.J, Sham, H.L, Trevillyan, J.M. | 登録日 | 2007-01-31 | 公開日 | 2007-04-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery and Structure-Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors. J.Med.Chem., 50, 2007
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7MJ2
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![BU of 7mj2 by Molmil](/molmil-images/mine/7mj2) | LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with Zn | 分子名称: | MAGNESIUM ION, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase, ZINC ION | 著者 | Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P. | 登録日 | 2021-04-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 118, 2021
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3B6E
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![BU of 3b6e by Molmil](/molmil-images/mine/3b6e) | Crystal structure of human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain | 分子名称: | Interferon-induced helicase C domain-containing protein 1, SODIUM ION | 著者 | Karlberg, T, Welin, M, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | 登録日 | 2007-10-29 | 公開日 | 2007-11-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain. To be Published
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7MJ0
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![BU of 7mj0 by Molmil](/molmil-images/mine/7mj0) | LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with adenosine monophosphate AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase | 著者 | Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P. | 登録日 | 2021-04-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 118, 2021
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3KNE
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![BU of 3kne by Molmil](/molmil-images/mine/3kne) | Carbonic Anhydrase II H64C mutant in complex with an in situ formed triazole | 分子名称: | (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, N-[(S)-(1-{2-oxo-2-[(3-sulfanylpropyl)amino]ethyl}-1H-1,2,3-triazol-5-yl)(phenyl)methyl]-4-sulfamoylbenzamide, ... | 著者 | Schulze-Wischeler, J, Heine, A, Klebe, G. | 登録日 | 2009-11-12 | 公開日 | 2011-05-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Stereo- and Regioselective Azide/Alkyne Cycloadditions in Carbonic Anhydrase II via Tethering, Monitored by Crystallography and Mass Spectrometry. Chemistry, 17, 2011
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2H3D
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![BU of 2h3d by Molmil](/molmil-images/mine/2h3d) | Crystal Structure of Mouse Nicotinamide Phosphoribosyltransferase/Visfatin/Pre-B Cell Colony Enhancing Factor in Complex with Nicotinamide Mononuleotide | 分子名称: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide phosphoribosyltransferase | 著者 | Wang, T, Zhang, X, Bheda, P, Revollo, J.R, Imai, S.I, Wolberger, C. | 登録日 | 2006-05-22 | 公開日 | 2006-06-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of Nampt/PBEF/visfatin, a mammalian NAD(+) biosynthetic enzyme. Nat.Struct.Mol.Biol., 13, 2006
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2OSC
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![BU of 2osc by Molmil](/molmil-images/mine/2osc) | Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors | 分子名称: | Angiopoietin-1 receptor, N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE | 著者 | Bellon, S.F, Kim, J. | 登録日 | 2007-02-05 | 公開日 | 2007-03-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
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7MUY
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![BU of 7muy by Molmil](/molmil-images/mine/7muy) | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 5 | 分子名称: | DUF2807 domain-containing protein, DotC, DotD, ... | 著者 | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | 登録日 | 2021-05-14 | 公開日 | 2021-10-06 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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7MUQ
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![BU of 7muq by Molmil](/molmil-images/mine/7muq) | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 1 | 分子名称: | DUF2807 domain-containing protein, DotC, DotD, ... | 著者 | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | 登録日 | 2021-05-14 | 公開日 | 2021-10-06 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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7MUW
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![BU of 7muw by Molmil](/molmil-images/mine/7muw) | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 4 | 分子名称: | DUF2807 domain-containing protein, DotC, DotD, ... | 著者 | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | 登録日 | 2021-05-14 | 公開日 | 2021-10-06 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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