3KF2
The HCV NS3/NS4A protease apo structure
Summary for 3KF2
Entry DOI | 10.2210/pdb3kf2/pdb |
Related | 3KEE |
Descriptor | Polyprotein, 19-mer peptide from Genome polyprotein, ZINC ION, ... (4 entities in total) |
Functional Keywords | hcv, ns3, protease, apo, hydrolase |
Biological source | Hepatitis C virus More |
Total number of polymer chains | 4 |
Total formula weight | 47385.35 |
Authors | Lindberg, J.D.,Nystrom, S.,Cummings, M.D. (deposition date: 2009-10-27, release date: 2010-03-09, Last modification date: 2023-11-01) |
Primary citation | Cummings, M.D.,Lindberg, J.D.,Lin, T.-I.,de Kock, H.,Lenz, O.,Lilja, E.,Fellander, S.,Baraznenok, V.,Nystrom, S.,Nilsson, M.,Vrang, L.,Edlund, M.,Rosenquist, A.,Samuelsson, B.,Raboisson, P.,Simmen, K. Induced-Fit Binding of the Macrocyclic Noncovalent Inhibitor TMC435 to its HCV NS3/NS4A Protease Target Angew.Chem.Int.Ed.Engl., 49:1652-1655, 2010 Cited by PubMed: 20166108DOI: 10.1002/anie.200906696 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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