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2PZ5
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Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549T Mutation Responsible for Pfeiffer Syndrome
分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Chen, H, Mohammadi, M.
登録日2007-05-17
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
3H06
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BU of 3h06 by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR2 bound to the willardiine antagonist, UBP282
分子名称: 4-({3-[(2R)-2-amino-2-carboxyethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)benzoic acid, Glutamate receptor 2
著者Ahmed, A.H, Oswald, R.E.
登録日2009-04-08
公開日2009-05-05
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain.
Biochemistry, 48, 2009
3AXG
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Structure of 6-aminohexanoate-oligomer hydrolase
分子名称: Endotype 6-aminohexanoat-oligomer hydrolase, SODIUM ION
著者Negoro, S, Shibata, N, Tanaka, Y, Yasuhira, K, Shibata, H, Hashimoto, H, Lee, Y.H, Ohshima, S, Santa, R, Mochiji, K, Goto, Y, Ikegami, T, Nagai, K, Kato, D, Takeo, M, Higuchi, Y.
登録日2011-04-04
公開日2011-12-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structure of nylon hydrolase and mechanism of nylon-6 hydrolysis
J.Biol.Chem., 287, 2012
3AX7
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Bovine Xanthine Oxidase, protease cleaved form
分子名称: 2-HYDROXYBENZOIC ACID, BICARBONATE ION, CALCIUM ION, ...
著者Ishikita, H, Eger, B.T, Pai, E.F, Okamoto, K, Nishino, T.
登録日2011-03-30
公開日2012-02-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Protein conformational gating of enzymatic activity in xanthine oxidoreductase
J.Am.Chem.Soc., 134, 2012
2JJN
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Structure of closed cytochrome P450 EryK
分子名称: CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Savino, C, Sciara, G, Miele, A.E, Kendrew, S.G, Vallone, B.
登録日2008-04-15
公開日2009-07-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.
J.Biol.Chem., 284, 2009
3AX9
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Bovine xanthine oxidase, protease cleaved form
分子名称: 2-HYDROXYBENZOIC ACID, BICARBONATE ION, CALCIUM ION, ...
著者Ishikita, H, Eger, B.T, Pai, E.F, Okamoto, K, Nishino, T.
登録日2011-03-31
公開日2012-02-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Protein conformational gating of enzymatic activity in xanthine oxidoreductase
J.Am.Chem.Soc., 134, 2012
2JJO
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BU of 2jjo by Molmil
Structure of cytochrome P450 EryK in complex with its natural substrate erD
分子名称: CYTOCHROME P450 113A1, Erythromycin D, PROTOPORPHYRIN IX CONTAINING FE
著者Savino, C, Sciara, G, Miele, A.E, Kendrew, S.G, Vallone, B.
登録日2008-04-15
公開日2009-07-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.
J.Biol.Chem., 284, 2009
3AYT
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BU of 3ayt by Molmil
TTHB071 protein from Thermus thermophilus HB8
分子名称: Putative uncharacterized protein TTHB071, ZINC ION
著者Nakane, S, Wakamatsu, T, Fukui, K, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-05-17
公開日2011-10-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献In vivo, in vitro, and x-ray crystallographic analyses suggest the involvement of an uncharacterized triose-phosphate isomerase (TIM) barrel protein in protection against oxidative stress
J.Biol.Chem., 286, 2011
7FD6
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BU of 7fd6 by Molmil
Crystal structure of SmChiA in complex with 6a
分子名称: 11-methyl-3-(pyridin-3-ylmethyl)-4H-pyrimido[5'',4'':5',6']pyrido[2',3':4,5]pyrimido[1,2-b]pyridine-4,6(3H)-dione, Chitinase A
著者Xi, J, Qing, Y.
登録日2021-07-16
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Discovery of Conformation Constrained Tetracyclic Compounds as potent Chitinase OfChi-h inhibitor with novel binding mode
To Be Published
2Q14
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BU of 2q14 by Molmil
Crystal structure of Phosphohydrolase (BT4208) from Bacteroides thetaiotaomicron VPI-5482 at 2.20 A resolution
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2007-05-23
公開日2007-06-12
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Phosphohydrolase (BT4208) from Bacteroides thetaiotaomicron VPI-5482 at 2.20 A resolution
To be published
3HBE
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BU of 3hbe by Molmil
Class IV chitinase structure from Picea abies at 1.55A
分子名称: 2-METHOXYETHANOL, ACETATE ION, Class IV chitinase Chia4-Pa2, ...
著者Ubhayasekera, W, Mowbray, S.L.
登録日2009-05-04
公開日2009-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The first crystal structures of a family 19 class IV chitinase: the enzyme from Norway spruce.
Plant Mol.Biol., 71, 2009
3AY5
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Crystal structure of HHM (human homologue of murine maternal Id-like molecule)
分子名称: Cyclin-D1-binding protein 1
著者Seto, A, Ishitani, R, Nureki, O.
登録日2011-04-28
公開日2012-03-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition.
Embo J., 31, 2012
7FF4
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BU of 7ff4 by Molmil
The crystal structure of Clostridium cellulolyticum LacI family transcriptional regulator Ccel_1438
分子名称: Transcriptional regulator, LacI family
著者Zhang, N, Ge, H.
登録日2021-07-22
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The crystal structure of Clostridium cellulolyticum LacI family transcriptional regulator Ccel_1438
To Be Published
3HBV
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BU of 3hbv by Molmil
PrtC methionine mutants: M226A in-house
分子名称: CALCIUM ION, CHLORIDE ION, Secreted protease C, ...
著者Oberholzer, A.E, Bumann, M, Hege, T, Russo, S, Baumann, U.
登録日2009-05-05
公開日2009-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site
Biol.Chem., 390, 2009
3AYV
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BU of 3ayv by Molmil
TTHB071 protein from Thermus thermophilus HB8 soaking with ZnCl2
分子名称: Putative uncharacterized protein TTHB071, ZINC ION
著者Nakane, S, Wakamatsu, T, Fukui, K, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-05-17
公開日2011-10-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献In vivo, in vitro, and x-ray crystallographic analyses suggest the involvement of an uncharacterized triose-phosphate isomerase (TIM) barrel protein in protection against oxidative stress
J.Biol.Chem., 286, 2011
2Q7U
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BU of 2q7u by Molmil
Crystal Structure of the F plasmid TraI Relaxase Domain with the Scissile Thymidine Base and Imidodiphosphate
分子名称: IMIDO DIPHOSPHATE, MAGNESIUM ION, Protein traI, ...
著者Lujan, S.A, Redinbo, M.R.
登録日2007-06-07
公開日2008-05-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PGW
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BU of 2pgw by Molmil
Crystal structure of a putative muconate cycloisomerase from Sinorhizobium meliloti 1021
分子名称: GLYCEROL, Muconate cycloisomerase
著者Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-04-10
公開日2007-04-24
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of a putative muconate cycloisomerase from Sinorhizobium meliloti 1021
To be Published
2JK6
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BU of 2jk6 by Molmil
Structure of Trypanothione Reductase from Leishmania infantum
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TRYPANOTHIONE REDUCTASE
著者Baiocco, P, Colotti, G, Franceschini, S, Ilari, A.
登録日2008-08-21
公開日2009-04-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular Basis of Antimony Treatment in Leishmaniasis.
J.Med.Chem., 52, 2009
2JM5
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BU of 2jm5 by Molmil
Solution Structure of the RGS domain from human RGS18
分子名称: Regulator of G-protein signaling 18
著者Higman, V.A, Leidert, M, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G, Yang, X, Brockmann, C, Schmieder, P, Diehl, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC)
登録日2006-10-11
公開日2006-10-24
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
7FJD
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BU of 7fjd by Molmil
Cryo-EM structure of a membrane protein(WT)
分子名称: CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ...
著者Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z.
登録日2021-08-03
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.
Mol.Cell, 82, 2022
3GLF
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BU of 3glf by Molmil
Crystal Structure of the Ecoli Clamp Loader Bound to Primer-Template DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(*CP*TP*GP*GP*CP*CP*TP*AP*TP*A)-3'), ...
著者Simonetta, K.R, Kuriyan, J.
登録日2009-03-12
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.388 Å)
主引用文献The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
Cell(Cambridge,Mass.), 137, 2009
2Q9F
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BU of 2q9f by Molmil
Crystal structure of human cytochrome P450 46A1 in complex with cholesterol-3-sulphate
分子名称: CHOLEST-5-EN-3-YL HYDROGEN SULFATE, Cytochrome P450 46A1, GLYCEROL, ...
著者White, M.A, Mast, N.V, Johnson, E.F, Stout, C.D, Pikuleva, I.A.
登録日2007-06-12
公開日2008-06-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain.
Proc.Natl.Acad.Sci.Usa, 105, 2008
7FJE
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BU of 7fje by Molmil
Cryo-EM structure of a membrane protein(LL)
分子名称: CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ...
著者Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z.
登録日2021-08-03
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.
Mol.Cell, 82, 2022
7FAX
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Complex structure of TbLeo1 and LW domain from Trypanosoma brucei
分子名称: TbLW, TbLeo1 peptide
著者Liao, S, Gao, J, Tu, X.
登録日2021-07-07
公開日2022-07-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
7FJF
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Cryo-EM structure of a membrane protein(CS)
分子名称: CHOLEST-5-EN-3-YL HYDROGEN SULFATE, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ...
著者Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z.
登録日2021-08-03
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.
Mol.Cell, 82, 2022

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