PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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2HX2	Bovine eNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine 分子名称: (4S)-N-{4-AMINO-5-[(2-AMINOETHYL)(HYDROXYAMINO]-PENTYL}-N'-NITROGUANIDINE, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... 著者 Igarashi, J, Li, H, Poulos, T.L. 登録日 2006-08-02 公開日 2007-04-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-Based Design and Synthesis of N(omega)-Nitro-l-Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water. J.Med.Chem., 50, 2007
2HX3	Rat nNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine 分子名称: (4S)-N-{4-AMINO-5-[(2-AMINOETHYL)(HYDROXYAMINO]-PENTYL}-N'-NITROGUANIDINE, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... 著者 Igarashi, J, Li, H, Poulos, T.L. 登録日 2006-08-02 公開日 2007-04-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-Based Design and Synthesis of N(omega)-Nitro-l-Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water. J.Med.Chem., 50, 2007
2JH6	Human Thrombin Hirugen Inhibitor complex 分子名称: 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE, CALCIUM ION, HIRUDIN IIIA, ... 著者 Senger, S, Chan, C, Convery, M.A, Hubbard, J.A, Young, R.J, Shah, G.P, Watson, N.S. 登録日 2007-02-20 公開日 2007-05-08 最終更新日 2013-08-07 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Sulfonamide-Related Conformational Effects and Their Importance in Structure-Based Design. Bioorg.Med.Chem.Lett., 17, 2007
2LEG	Membrane protein complex DsbB-DsbA structure by joint calculations with solid-state NMR and X-ray experimental data 分子名称: Disulfide bond formation protein B, Thiol:disulfide interchange protein DsbA, UBIQUINONE-1, ... 著者 Tang, M, Sperling, L.J, Berthold, D.A, Schwieters, C.D, Nesbitt, A.E, Nieuwkoop, A.J, Gennis, R.B, Rienstra, C.M. 登録日 2011-06-15 公開日 2011-10-26 最終更新日 2023-06-14 実験手法 SOLID-STATE NMR 主引用文献 High-resolution membrane protein structure by joint calculations with solid-state NMR and X-ray experimental data. J.Biomol.Nmr, 51, 2011
2HDS	AmpC beta-lactamase in complex with 4-Methanesulfonylamino benzoic acid 分子名称: 4-[(METHYLSULFONYL)AMINO]BENZOIC ACID, Beta-lactamase, PHOSPHATE ION, ... 著者 Babaoglu, K, Shoichet, B.K. 登録日 2006-06-20 公開日 2006-11-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Deconstructing fragment-based inhibitor discovery Nat.Chem.Biol., 2, 2006
3UVF	Expanding LAGALIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Intron-encoded DNA endonuclease I-HjeMI, ... 著者 Jacoby, K, Metzger, M, Shen, B, Jarjour, J, Stoddard, B, Scharenberg, A. 登録日 2011-11-29 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space. Nucleic Acids Res., 40, 2012
2LR1	Structural Mechanism for Bax Inhibition by Cytomegalovirus Protein vMIA 分子名称: Apoptosis regulator BAX, Immediate early glycoprotein 著者 Ma, J. 登録日 2012-03-20 公開日 2012-12-05 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural mechanism of Bax inhibition by cytomegalovirus protein vMIA. Proc.Natl.Acad.Sci.USA, 109, 2012
2L7L	Solution structure of Ca2+/calmodulin complexed with a peptide representing the calmodulin-binding domain of calmodulin kinase I 分子名称: CALCIUM ION, Calcium/calmodulin-dependent protein kinase type 1, Calmodulin 著者 Gifford, J.L, Ishida, H, Vogel, H.J. 登録日 2010-12-13 公開日 2011-05-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Fast methionine-based solution structure determination of calcium-calmodulin complexes. J.Biomol.Nmr, 50, 2011
2L78	DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME 著者 Hurley, J.H, Matthews, B.W. 登録日 1992-01-22 公開日 1993-04-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme. J.Mol.Biol., 224, 1992
3VK8	Crystal structure of DNA-glycosylase bound to DNA containing Thymine glycol 分子名称: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(CTG)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), GLYCEROL, ... 著者 Imamura, K, Averill, A, Wallace, S.S, Doublie, S. 登録日 2011-11-10 公開日 2011-12-14 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural characterization of viral ortholog of human DNA glycosylase NEIL1 bound to thymine glycol or 5-hydroxyuracil-containing DNA J.Biol.Chem., 287, 2012
2D4U	Crystal Structure of the ligand binding domain of the bacterial serine chemoreceptor Tsr 分子名称: Methyl-accepting chemotaxis protein I 著者 Imada, K, Tajima, H, Namba, K, Sakuma, M, Homma, M, Kawagishi, I. 登録日 2005-10-24 公開日 2006-11-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Ligand specificity determined by differentially arranged common ligand-binding residues in the bacterial amino acid chemoreceptors Tsr and Tar. J.Biol.Chem., 2011
4LUO	Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions 分子名称: 1-(3-methylphenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid, Replication protein A 70 kDa DNA-binding subunit 著者 Feldkamp, M.D, Frank, A.O, Kennedy, J.P, Waterson, A.G, Olejniczak, E.T, Pelz, N.F, Patrone, J.D, Vangamudi, B, Camper, D.V, Rossanese, O.W, Fesik, S.W, Chazin, W.J. 登録日 2013-07-25 公開日 2013-12-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach. J.Med.Chem., 56, 2013
2RAW	Crystal structure of the Borealin-Survivin complex 分子名称: Baculoviral IAP repeat-containing protein 5, Borealin, ZINC ION 著者 Hymowitz, S.G. 登録日 2007-09-17 公開日 2007-10-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The mitotic regulator Survivin binds as a monomer to its functional interactor Borealin. J.Biol.Chem., 282, 2007
5HIW	Sorangium cellulosum So Ce56 cytochrome P450 260B1 分子名称: Cytochrome P450 CYP260B1, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Salamanca-Pinzon, S.G, Carius, Y, Khatri, Y, Bernhardt, R, Lancaster, C.R.D. 登録日 2016-01-12 公開日 2016-08-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-function analysis for the hydroxylation of Delta 4 C21-steroids by the myxobacterial CYP260B1. Febs Lett., 590, 2016
4LRA	Phosphopentomutase S154G variant 分子名称: GLYCEROL, MANGANESE (II) ION, Phosphopentomutase 著者 Birmingham, W.A, Starbird, C.A, Panosian, T.D, Nannemann, D.P, Iverson, T.M, Bachmann, B.O. 登録日 2013-07-19 公開日 2013-07-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Bioretrosynthetic construction of a didanosine biosynthetic pathway. Nat.Chem.Biol., 10, 2014
4LV7	Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase E82C/S142C 分子名称: ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Inositol-pentakisphosphate 2-kinase, ... 著者 Gosein, V, Miller, G.J. 登録日 2013-07-26 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Conformational stability of inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) dictates its substrate selectivity. J. Biol. Chem., 288, 2013
2RBL	High resolution design of a protein loop 分子名称: Tenascin 著者 Hu, X, Wang, H, Ke, H, Kuhlman, B. 登録日 2007-09-19 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 High-resolution design of a protein loop. Proc.Natl.Acad.Sci.Usa, 104, 2007
4UNM	Structure of Galactose Oxidase homologue from Streptomyces lividans 分子名称: ACETATE ION, COPPER (II) ION, SECRETED PROTEIN 著者 Chaplin, A.K, Hough, M.A, Worrall, J.A.R. 登録日 2014-05-29 公開日 2015-06-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Glxa is a New Structural Member of the Radical Copper Oxidase Family and is Required for Glycan Deposition at Hyphal Tips and Morphogenesis of Streptomyces Lividans. Biochem.J., 469, 2015
4MCK	Crystal structure of Family GH19, Class IV chitinase from Zea mays 分子名称: Chitinase 著者 Chaudet, M.M, Rose, D.R. 登録日 2013-08-21 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystallographic structure of ChitA, a glycoside hydrolase family 19, plant class IV chitinase from Zea mays. Protein Sci., 23, 2014
5XHN	Crystal structure of Frog M-ferritin K104E mutant 分子名称: CHLORIDE ION, Ferritin, middle subunit, ... 著者 Jagdev, M.K, Vasudevan, D. 登録日 2017-04-21 公開日 2017-08-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Surface charge dependent separation of modified and hybrid ferritin in native PAGE: Impact of lysine 104 Biochim. Biophys. Acta, 1865, 2017
5HQX	Crystal structure of maize cytokinin oxidase/dehydrogenase 4 (ZmCKO4) in complex with phenylurea inhibitor HETDZ 分子名称: 1-[2-(2-hydroxyethyl)phenyl]-3-(1,2,3-thiadiazol-5-yl)urea, Cytokinin dehydrogenase 4, FLAVIN-ADENINE DINUCLEOTIDE 著者 Kopecny, D, Koncitikova, R, Briozzo, P. 登録日 2016-01-22 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Novel thidiazuron-derived inhibitors of cytokinin oxidase/dehydrogenase. Plant Mol.Biol., 92, 2016
4LRD	Phosphopentomutase 4H11 variant 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MANGANESE (II) ION, ... 著者 Birmingham, W.A, Starbird, C.A, Panosian, T.D, Nannemann, D.P, Iverson, T.M, Bachmann, B.O. 登録日 2013-07-19 公開日 2013-07-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Bioretrosynthetic construction of a didanosine biosynthetic pathway. Nat.Chem.Biol., 10, 2014
5HV9	Human LTC4S mutant-S36E 分子名称: GLUTATHIONE, Leukotriene C4 synthase, SULFATE ION 著者 Thulasingam, M, Ahmad, H.R.S, Rinaldo-Matthis, A, Haeggstrom, J.Z. 登録日 2016-01-28 公開日 2016-07-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity. J.Biol.Chem., 291, 2016
5HWE	high resolution structure of barbiturase 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Barbiturase, MAGNESIUM ION, ... 著者 Peat, T.S, Scott, C. 登録日 2016-01-29 公開日 2017-02-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes. Appl. Environ. Microbiol., 83, 2017
4ZX2	Co-crystal structures of PP5 in complex with 5-methyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid 分子名称: (1S,2R,3S,4R,5S)-5-methyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... 著者 Chattopadhyay, D, Swingle, M.R, Salter, E.A, Wierzbicki, A, Honkanen, R.E. 登録日 2015-05-19 公開日 2016-04-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C. Biochem. Pharmacol., 109, 2016

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