PDB: 183105 件ウェブページステータス検索Chemie searchBIRD

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1DGE	AN ALKALI METAL ION SIZE-DEPENDENT SWITCH IN THE ACTIVE SITE STRUCTURE OF DIALKYLGLYCINE DECARBOXYLASE 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIALKYLGLYCINE DECARBOXYLASE, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Hohenester, E, Jansonius, J.N. 登録日 1994-06-29 公開日 1994-09-30 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 An alkali metal ion size-dependent switch in the active site structure of dialkylglycine decarboxylase. Biochemistry, 33, 1994
3V39	Bd3459, A Predatory Peptidoglycan Endopeptidase from Bdellovibrio bacteriovorus 分子名称: 2-AMINOETHANESULFONIC ACID, D-alanyl-D-alanine carboxypeptidase, SULFATE ION, ... 著者 Lovering, A.L, Lerner, T.R, Sockett, R.E. 登録日 2011-12-13 公開日 2012-02-22 最終更新日 2012-04-11 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Specialized peptidoglycan hydrolases sculpt the intra-bacterial niche of predatory Bdellovibrio and increase population fitness. Plos Pathog., 8, 2012
2CQB	Solution Structure of the RNA recognition motif in Peptidyl-prolyl cis-trans isomerase E 分子名称: Peptidyl-prolyl cis-trans isomerase E 著者 Someya, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-19 公開日 2005-11-19 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the RNA recognition motif in Peptidyl-prolyl cis-trans isomerase E To be Published
2QGF	Structure of regulatory chain mutant H20A of asparate transcarbamoylase from E. coli 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION 著者 Stec, B, Williams, M.K, Stieglitz, K.A, Kantrowitz, E.R. 登録日 2007-06-28 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Comparison of two T-state structures of regulatory-chain mutants of Escherichia coli aspartate transcarbamoylase suggests that His20 and Asp19 modulate the response to heterotropic effectors. Acta Crystallogr.,Sect.D, 63, 2007
3UPF	Crystal structure of murine norovirus RNA-dependent RNA polymerase bound to NF023 分子名称: 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, RNA-dependent RNA polymerase, SULFATE ION 著者 Milani, M, Mastrangelo, E, Bolognesi, M. 登録日 2011-11-18 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases. J.Mol.Biol., 419, 2012
6DL2	BRD4 bromodomain 1 in complex with HYB157 分子名称: 1,2-ETHANEDIOL, 3-benzyl-2,9-dimethyl-4H,6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,4]oxazepine, Bromodomain-containing protein 4 著者 Meagher, J.L, Stuckey, J.A. 登録日 2018-05-31 公開日 2019-04-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression. J. Med. Chem., 61, 2018
2MBR	MURB WILD TYPE, COMPLEX WITH ENOLPYRUVYL-UDP-N-ACETYLGLUCOSAMINE 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, URIDINE DIPHOSPHO-N-ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID 著者 Benson, T.E, Walsh, C.T, Hogle, J.M. 登録日 1996-11-08 公開日 1997-04-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution. Biochemistry, 36, 1997
3E8Q	X-ray structure of rat arginase I-T135A: the unliganded complex 分子名称: Arginase-1, MANGANESE (II) ION 著者 Shishova, E.Y, Di Costanzo, L, Emig, F.A, Ash, D.E, Christianson, D.W. 登録日 2008-08-20 公開日 2008-12-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Probing the specificity determinants of amino acid recognition by arginase. Biochemistry, 48, 2009
1ACW	SOLUTION NMR STRUCTURE OF P01, A NATURAL SCORPION PEPTIDE STRUCTURALLY ANALOGOUS TO SCORPION TOXINS SPECIFIC FOR APAMIN-SENSITIVE POTASSIUM CHANNEL, 25 STRUCTURES 分子名称: NATURAL SCORPION PEPTIDE P01 著者 Blanc, E, Fremont, V, Sizun, P, Meunier, S, Van Rietschoten, J, Thevand, A, Bernassau, J.M, Darbon, H. 登録日 1997-02-10 公開日 1997-04-01 最終更新日 2022-02-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of P01, a natural scorpion peptide structurally analogous to scorpion toxins specific for apamin-sensitive potassium channel. Proteins, 24, 1996
7RDN	Crystal structure of S. cerevisiae pre-mRNA leakage protein 39 (Pml39) 分子名称: Pre-mRNA leakage protein 39, ZINC ION 著者 Hashimoto, H, Ramirez, D.H, Pawlak, N, Blobel, G, Palancade, B, Debler, E.W. 登録日 2021-07-09 公開日 2022-07-27 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structure of the pre-mRNA leakage 39-kDa protein reveals a single domain of integrated zf-C3HC and Rsm1 modules. Sci Rep, 12, 2022
1DJ3	STRUCTURES OF ADENYLOSUCCINATE SYNTHETASE FROM TRITICUM AESTIVUM AND ARABIDOPSIS THALIANA 分子名称: ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE 著者 Prade, L, Cowan-Jacob, S.W, Chemla, P, Potter, S, Ward, E, Fonne-Pfister, R. 登録日 1999-12-01 公開日 2000-03-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana. J.Mol.Biol., 296, 2000
1DO6	CRYSTAL STRUCTURE OF SUPEROXIDE REDUCTASE IN THE OXIDIZED STATE AT 2.0 ANGSTROM RESOLUTION 分子名称: FE (III) ION, SUPEROXIDE REDUCTASE 著者 Yeh, A.P, Hu, Y, Jenney Junior, F.E, Adams, M.W, Rees, D.C. 登録日 1999-12-19 公開日 2000-03-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of the superoxide reductase from Pyrococcus furiosus in the oxidized and reduced states. Biochemistry, 39, 2000
6E0K	Structure of Rhodothermus marinus CdnE c-UMP-AMP synthase 分子名称: cGAS/DncV-like nucleotidyltransferase in E. coli homolog 著者 Eaglesham, J.B, Whiteley, A.T, de Oliveira Mann, C.C, Morehouse, B.R, Nieminen, E.A, King, D.S, Lee, A.S.Y, Mekalanos, J.J, Kranzusch, P.J. 登録日 2018-07-06 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature, 567, 2019
1IDT	STRUCTURAL STUDIES ON A PRODRUG-ACTIVATING SYSTEM-CB1954 AND FMN-DEPENDENT NITROREDUCTASE 分子名称: 5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE, FLAVIN MONONUCLEOTIDE, MINOR FMN-DEPENDENT NITROREDUCTASE 著者 Johansson, E, Parkinson, G.N, Denny, W.A, Neidle, S. 登録日 2001-04-05 公開日 2003-09-16 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form. J.Med.Chem., 46, 2003
3LPQ	Human MitoNEET with 2Fe-2S Coordinating Ligand His 87 Replaced With Cys 分子名称: CDGSH iron sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER 著者 Conlan, A.R, Homer, C, Axelrod, H.L, Cohen, A.E, Abresch, E.C, Zuris, J, Nechushtai, R, Paddock, M.L, Jennings, P.A. 登録日 2010-02-05 公開日 2011-06-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment. Acta Crystallogr.,Sect.D, 67, 2011
6E0M	Structure of Elizabethkingia meningoseptica CdnE cyclic dinucleotide synthase 分子名称: DIPHOSPHATE, cGAS/DncV-like nucleotidyltransferase in E. coli homolog 著者 Eaglesham, J.B, Whiteley, A.T, de Oliveira Mann, C.C, Morehouse, B.R, Nieminen, E.A, King, D.S, Lee, A.S.Y, Mekalanos, J.J, Kranzusch, P.J. 登録日 2018-07-06 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature, 567, 2019
3QMS	Crystal structure of the mutant T159V,V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 分子名称: 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. 登録日 2011-02-05 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
3QF0	Crystal structure of the mutant T159V,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 分子名称: 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. 登録日 2011-01-20 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
3QMR	Crystal structure of the mutant R160A,V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 分子名称: 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-phosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. 登録日 2011-02-05 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3213 Å) 主引用文献 Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
1EUW	ATOMIC RESOLUTION STRUCTURE OF E. COLI DUTPASE 分子名称: DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, ETHYL MERCURY ION, GLYCEROL 著者 Gonzalez, A, Cedergren, E, Larsson, G, Persson, R. 登録日 2000-04-17 公開日 2000-05-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Atomic resolution structure of Escherichia coli dUTPase determined ab initio. Acta Crystallogr.,Sect.D, 57, 2001
1EV8	CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI 分子名称: THYMIDYLATE SYNTHASE 著者 Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L. 登録日 2000-04-19 公開日 2000-05-03 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Catalytic cysteine of thymidylate synthase is activated upon substrate binding. Biochemistry, 39, 2000
3QMT	Crystal structure of the mutant V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 分子名称: 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. 登録日 2011-02-05 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3202 Å) 主引用文献 Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
1RQD	deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form with the inhibitor GC7 bound in the active site 分子名称: 1-GUANIDINIUM-7-AMINOHEPTANE, Deoxyhypusine synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Umland, T.C, Wolff, E.C, Park, M.-H, Davies, D.R. 登録日 2003-12-04 公開日 2004-07-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A New Crystal Structure of Deoxyhypusine Synthase Reveals the Configuration of the Active Enzyme and of an Enzyme-NAD-Inhibitor Ternary Complex J.Biol.Chem., 279, 2004
5KWG	Crystal structure of extracellular domain of HER2 in complex with Fcab H10-03-6 分子名称: Ig gamma-1 chain C region, Receptor tyrosine-protein kinase erbB-2 著者 Humm, A, Lobner, E, Goritzer, K, Mlynek, G, Obinger, C, Djinovic-Carugo, K. 登録日 2016-07-18 公開日 2017-04-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies. Structure, 25, 2017
2ZED	Crystal structure of the human glutaminyl cyclase mutant S160A at 1.7 angstrom resolution 分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION 著者 Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. 登録日 2007-12-12 公開日 2008-04-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008

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