Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3QMR

Crystal structure of the mutant R160A,V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP

Summary for 3QMR
Entry DOI10.2210/pdb3qmr/pdb
Related3LTP
DescriptorOrotidine 5'-phosphate decarboxylase, 6-HYDROXYURIDINE-5'-PHOSPHATE (3 entities in total)
Functional Keywordstim barrel fold, 5'-monophosphate decarboxylase, inhibitor bmp, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological sourceMethanothermobacter thermautotrophicus str. Delta H
Total number of polymer chains2
Total formula weight50221.42
Authors
Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Gerlt, J.A.,Almo, S.C. (deposition date: 2011-02-05, release date: 2012-02-08, Last modification date: 2023-09-13)
Primary citationDesai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A.
Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme.
Biochemistry, 51:8665-8678, 2012
Cited by
PubMed: 23030629
DOI: 10.1021/bi301188k
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.3213 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon