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8G0M
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Structure of complex between TV6.6 and CD98hc ECD
分子名称: 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, TETRAETHYLENE GLYCOL, ...
著者Kariolis, M.S, Lexa, K, Liau, N.P.D, Srivastava, D, Tran, H, Wells, R.C.
登録日2023-01-31
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献CD98hc is a target for brain delivery of biotherapeutics.
Nat Commun, 14, 2023
1U5Y
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Crystal structure of murine APRIL, pH 8.0
分子名称: Tumor necrosis factor ligand superfamily member 13
著者Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G.
登録日2004-07-28
公開日2004-10-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
1U5Z
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The Crystal structure of murine APRIL, pH 8.5
分子名称: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13
著者Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G.
登録日2004-07-28
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
1U5X
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Crystal structure of murine APRIL at pH 5.0
分子名称: Tumor necrosis factor ligand superfamily member 13
著者Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G.
登録日2004-07-28
公開日2004-10-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
5X69
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Human thymidylate synthase with a fragment bound in the dimer interface
分子名称: 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase
著者Chen, D, Jansson, A, Larsson, A, Nordlund, P.
登録日2017-02-21
公開日2017-06-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem., 292, 2017
4KC0
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mSTING
分子名称: Stimulator of interferon genes protein
著者Chin, K.H, Su, Y.C, Tu, J.L, Chou, S.H.
登録日2013-04-24
公開日2013-05-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING
Acta Crystallogr.,Sect.D, 69, 2013
4TLH
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BU of 4tlh by Molmil
Monoclinic Crystal Structure of EutL from Clostridium Perfringens
分子名称: CHLORIDE ION, Ethanolamine utilization protein EutL, SODIUM ION
著者Thompson, M.C, Yeates, T.O.
登録日2014-05-29
公開日2015-06-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism
Acta Crystallogr.,Sect.D, 2018
4KBY
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mSTING/c-di-GMP
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Stimulator of interferon genes protein
著者Chin, K.H, Su, Y.C, Tu, J.L, Chou, S.H.
登録日2013-04-24
公開日2013-05-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING
Acta Crystallogr.,Sect.D, 69, 2013
2LE6
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BU of 2le6 by Molmil
Structure of a dimeric all-parallel-stranded G-quadruplex stacked via the 5'-to-5' interface
分子名称: DNA (5'-D(*GP*IP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3')
著者Do, N.Q, Lim, K.W, Teo, M.H, Heddi, B, Phan, A.T.
登録日2011-06-10
公開日2011-08-31
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activity
Nucleic Acids Res., 2011
7Q1Z
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BU of 7q1z by Molmil
Structure of formaldehyde cross-linked SARS-CoV-2 S glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Sulbaran, G, Effantin, G, Schoehn, G, Weissenhorn, W.
登録日2021-10-22
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Immunization with synthetic SARS-CoV-2 S glycoprotein virus-like particles protects macaques from infection.
Cell Rep Med, 3, 2022
1Z9N
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X-Ray structure of a Cu-Zn superoxide dismutase from Haemophilus ducreyi with haem bound at the dimer interface
分子名称: COPPER (II) ION, PROTOPORPHYRIN IX CONTAINING FE, Superoxide dismutase [Cu-Zn], ...
著者Djinovic Carugo, K, Toeroe, I.
登録日2005-04-03
公開日2006-09-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of heme binding in the Cu,Zn superoxide dismutase from Haemophilus ducreyi.
J.Mol.Biol., 386, 2009
1UJZ
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BU of 1ujz by Molmil
Crystal structure of the E7_C/Im7_C complex; a computationally designed interface between the colicin E7 DNase and the Im7 Immunity protein
分子名称: Designed Colicin E7 DNase, Designed Colicin E7 immunity protein
著者Kortemme, T, Joachimiak, L.A, Bullock, A.N, Schuler, A.D, Stoddard, B.L, Baker, D.
登録日2003-08-13
公開日2004-04-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Computational redesign of protein-protein interaction specificity
NAT.STRUCT.MOL.BIOL., 11, 2004
1J1L
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Crystal structure of human Pirin: a Bcl-3 and Nuclear factor I interacting protein and a cupin superfamily member
分子名称: FE (II) ION, Pirin
著者Pang, H, Bartlam, M, Zeng, Q, Gao, G.F, Rao, Z.
登録日2002-12-10
公開日2003-12-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor
J.Biol.Chem., 279, 2004
5UPL
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BU of 5upl by Molmil
CDC42 binds PAK4 via an extended GTPase-effector inteface - 2 peptide: PAK4FL, CDC42 - UNREFINED
分子名称: Cell division control protein 42 homolog, Serine/threonine-protein kinase PAK 4
著者Ha, B.H, Boggon, T.J.
登録日2017-02-03
公開日2017-12-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献CDC42 binds PAK4 via an extended GTPase-effector interface.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5CHY
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BU of 5chy by Molmil
STRUCTURE OF CHEMOTAXIS PROTEIN CHEY
分子名称: CALCIUM ION, CHEY
著者Zhu, X, Rebello, J, Matsumura, P, Volz, K.
登録日1996-08-29
公開日1996-12-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of CheY mutants Y106W and T87I/Y106W. CheY activation correlates with movement of residue 106.
J.Biol.Chem., 272, 1997
3L82
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X-ray Crystal structure of TRF1 and Fbx4 complex
分子名称: F-box only protein 4, Telomeric repeat-binding factor 1
著者Zeng, Z.X, Wang, W, Yang, Y.T, Chen, Y, Yang, X.M, Diehl, J.A, Liu, X.D, Lei, M.
登録日2009-12-29
公開日2010-03-09
最終更新日2013-09-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of Selective Ubiquitination of TRF1 by SCF(Fbx4)
Dev.Cell, 18, 2010
3SLC
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BU of 3slc by Molmil
Crystal structure of apo form of acetate kinase (AckA) from Salmonella typhimurium
分子名称: 1,2-ETHANEDIOL, Acetate kinase
著者Chittori, S, Savithri, H.S, Murthy, M.R.N.
登録日2011-06-24
公開日2012-08-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and mechanistic investigations on Salmonella typhimurium acetate kinase (AckA): identification of a putative ligand binding pocket at the dimeric interface
Bmc Struct.Biol., 12, 2012
1SZR
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BU of 1szr by Molmil
A Dimer interface mutant of ornithine decarboxylase reveals structure of gem diamine intermediate
分子名称: N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-ORNITHINE, Ornithine decarboxylase, ...
著者Jackson, L.K, Baldwin, J, Goldsmith, E.J, Phillips, M.A.
登録日2004-04-06
公開日2004-10-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase
Biochemistry, 43, 2004
2R30
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Crystal Structure of human GITRL mutant
分子名称: Tumor necrosis factor ligand superfamily member 18
著者Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
登録日2007-08-28
公開日2007-11-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.
Proc.Natl.Acad.Sci.USA, 104, 2007
3Q87
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Structure of E. cuniculi Mtq2-Trm112 complex responible for the methylation of eRF1 translation termination factor
分子名称: N6 adenine specific DNA methylase, Putative uncharacterized protein ECU08_1170, S-ADENOSYLMETHIONINE, ...
著者Liger, D, Mora, L, Lazar, N, Figaro, S, Henri, J, Scrima, N, Buckingham, R.H, van Tilbeurgh, H, Heurgue-Hamard, V, Graille, M.
登録日2011-01-06
公開日2011-05-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Mechanism of activation of methyltransferases involved in translation by the Trm112 'hub' protein
Nucleic Acids Res., 2011
1EMS
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CRYSTAL STRUCTURE OF THE C. ELEGANS NITFHIT PROTEIN
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ETHYL MERCURY ION, NIT-FRAGILE HISTIDINE TRIAD FUSION PROTEIN, ...
著者Pace, H.C, Hodawadekar, S.C, Draganescu, A, Huang, J, Bieganowski, P, Pekarsky, Y, Croce, C.M, Brenner, C.
登録日2000-03-17
公開日2000-07-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers.
Curr.Biol., 10, 2000
8D9V
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gamma-Arf1 homodimeric interface within AP-1, Arf1, Nef lattice on narrow membrane tubes
分子名称: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-06-11
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8DBF
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Human PRPS1 with ADP; Filament Interface
分子名称: 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Hvorecny, K.L, Kollman, J.M.
登録日2022-06-14
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Human PRPS1 filaments stabilize allosteric sites to regulate activity.
Nat.Struct.Mol.Biol., 30, 2023
8DBJ
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Human PRPS1 with Phosphate, ATP, and R5P; Filament Interface
分子名称: 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Hvorecny, K.L, Kollman, J.M.
登録日2022-06-14
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Human PRPS1 filaments stabilize allosteric sites to regulate activity.
Nat.Struct.Mol.Biol., 30, 2023
8DBM
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Human PRPS1 with Phosphate and PRPP; Filament Interface
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, PHOSPHATE ION, ...
著者Hvorecny, K.L, Kollman, J.M.
登録日2022-06-14
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Human PRPS1 filaments stabilize allosteric sites to regulate activity.
Nat.Struct.Mol.Biol., 30, 2023

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