7B9S
| Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | 分子名称: | EccB5, EccC5, EccD5, ... | 著者 | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | 登録日 | 2020-12-14 | 公開日 | 2021-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the mycobacterial ESX-5 type VII secretion system pore complex. Sci Adv, 7, 2021
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8JNB
| CRAF ras-binding domain chimera, ligand complex | 分子名称: | 2-[4-[[(2S)-1-ethanoyl-3-oxidanylidene-2H-indol-2-yl]methyl]-2-methoxy-phenoxy]ethanamide, RAF proto-oncogene serine/threonine-protein kinase, CRaf | 著者 | Kawamura, T, Kumasaka, T. | 登録日 | 2023-06-06 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Small-molecule RAS/RAF-binding Inhibitors Allosterically Disrupt RAF Conformation and Exert Efficacy Against Broad-spectrum RAS-driven Cancers To Be Published
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8GIY
| E. coli clamp loader with closed clamp | 分子名称: | Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ... | 著者 | Oakley, A.J, Xu, Z.-Q, Dixon, N.E. | 登録日 | 2023-03-14 | 公開日 | 2024-03-27 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli. Nat Commun, 15, 2024
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8GJ2
| E. coli clamp loader with closed clamp on primed template DNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Beta sliding clamp, DNA polymerase III subunit delta, ... | 著者 | Oakley, A.J, Xu, Z.-Q, Dixon, N.E. | 登録日 | 2023-03-14 | 公開日 | 2024-03-27 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli. Nat Commun, 15, 2024
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8JSV
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8UPR
| Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2023-10-23 | 公開日 | 2024-05-29 | 最終更新日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Structural basis of RfaH-mediated transcription-translation coupling. Nat.Struct.Mol.Biol., 2024
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8UR0
| Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, NusA, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2023-10-25 | 公開日 | 2024-05-29 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of RfaH-mediated transcription-translation coupling. Nat.Struct.Mol.Biol., 2024
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7BH7
| Room temperature, serial X-ray structure of the ertapenem-derived acylenzyme of CTX-M-15 (10 min soak) collected on fixed target chips at Diamond Light Source I24 | 分子名称: | (2~{S},3~{R},4~{R})-3-[5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-4-methyl-5-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-2-carboxylic acid, Beta-lactamase, CHLORIDE ION, ... | 著者 | Hinchliffe, P, Tooke, C.L, Butryn, A, Spencer, J. | 登録日 | 2021-01-10 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nat Commun, 12, 2021
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8JSY
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8GJ0
| E. coli clamp loader with open clamp on primed template DNA (form 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Beta sliding clamp, DNA polymerase III subunit delta, ... | 著者 | Oakley, A.J, Xu, Z.-Q, Dixon, N.E. | 登録日 | 2023-03-14 | 公開日 | 2024-03-27 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli. Nat Commun, 15, 2024
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7BAY
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7BH6
| Room temperature, serial X-ray structure of CTX-M-15 collected on fixed target chips at Diamond Light Source I24 | 分子名称: | Beta-lactamase, CHLORIDE ION, SODIUM ION, ... | 著者 | Hinchliffe, P, Tooke, C.L, Butryn, A, Spencer, J. | 登録日 | 2021-01-10 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nat Commun, 12, 2021
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7BH4
| XFEL structure of apo CTX-M-15 after mixing for 0.7 sec with ertapenem using a piezoelectric injector (PolyPico) | 分子名称: | Beta-lactamase, SULFATE ION | 著者 | Hinchliffe, P, Tooke, C.L, Butryn, A, Spencer, J. | 登録日 | 2021-01-10 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nat Commun, 12, 2021
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8JT0
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7BHN
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7BHK
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7BH5
| XFEL structure of the ertapenem-derived CTX-M-15 acylenzyme after mixing for 2 sec using a piezoelectric injector (PolyPico) | 分子名称: | (2~{S},3~{R},4~{R})-3-[5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-4-methyl-5-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-2-carboxylic acid, Beta-lactamase, CHLORIDE ION, ... | 著者 | Hinchliffe, P, Tooke, C.L, Butryn, A, Spencer, J. | 登録日 | 2021-01-10 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nat Commun, 12, 2021
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8KFS
| Crystal structure of ZmMOC1/nicked Holliday junction complex at ground state | 分子名称: | DNA (25-MER), DNA (33-MER), DNA (5'-D(P*CP*AP*CP*GP*AP*TP*TP*G)-3'), ... | 著者 | Zhang, D, Luo, Z, Lin, Z. | 登録日 | 2023-08-16 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | MOC1 cleaves Holliday junctions through a cooperative nick and counter-nick mechanism mediated by metal ions. Nat Commun, 15, 2024
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7BHM
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7BH3
| XFEL structure of CTX-M-15 resting state | 分子名称: | Beta-lactamase, CHLORIDE ION, SULFATE ION | 著者 | Hinchliffe, P, Tooke, C.L, Butryn, A, Spencer, J. | 登録日 | 2021-01-10 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nat Commun, 12, 2021
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7BG1
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7BHL
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8G9J
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8G9K
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8GA6
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