PDB: 37932 件ウェブページステータス検索Chemie searchBIRD

---

8GPE	Crystal structure of NDM-1 at pH5.5 (Succinate) in complex with hydrolyzed penicillin G 分子名称: (2R,4S)-2-{(R)-carboxy[(phenylacetyl)amino]methyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Metallo beta lactamase NDM-1, POTASSIUM ION, ... 著者 Shi, X, Dai, Y, Zhang, Q, Liu, W. 登録日 2022-08-26 公開日 2023-08-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Interplay between the beta-lactam side chain and an active-site mobile loop of NDM-1 in penicillin hydrolysis as a potential target for mechanism-based inhibitor design. Int.J.Biol.Macromol., 262, 2024
8GL3	De novo design of monomeric helical bundles for pH-controlled membrane lysis 分子名称: pRLB-519 著者 Goldbach, N, Bera, A.K, Baker, D, Kang, A. 登録日 2023-03-20 公開日 2023-09-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 De novo design of monomeric helical bundles for pH-controlled membrane lysis. Protein Sci., 32, 2023
8GRZ	X-ray crystal structure of V71C human neuroglobin mutant 分子名称: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE 著者 Lin, Y.W. 登録日 2022-09-03 公開日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray crystal structure of V71C human neuroglobin mutant To Be Published
7DMA	Crystal structure of FliM middle domain (46-231) with R49P substitution from Vibro alginolyticus 分子名称: Flagellar motor switch protein FliM 著者 Takekawa, N, Homma, M, Imada, K. 登録日 2020-12-03 公開日 2021-07-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 A slight bending of an alpha-helix in FliM creates a counterclockwise-locked structure of the flagellar motor in Vibrio. J.Biochem., 170, 2021
7DM9	Crystal structure of FliM middle domain (51-229) from Vibro alginolyticus 分子名称: Flagellar motor switch protein FliM 著者 Takekawa, N, Homma, M, Imada, K. 登録日 2020-12-02 公開日 2021-07-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 A slight bending of an alpha-helix in FliM creates a counterclockwise-locked structure of the flagellar motor in Vibrio. J.Biochem., 170, 2021
7DE2	iron and alpha-ketoglutarate-dependent endoperoxidase NvfI 分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, NvfI, ... 著者 Zhai, R, Mori, T, Abe, I. 登録日 2020-11-01 公開日 2021-07-14 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular insights into the endoperoxide formation by Fe(II)/ alpha-KG-dependent oxygenase NvfI. Nat Commun, 12, 2021
8JOK	Crystal structure of V30L mutated human transthyretin 分子名称: MAGNESIUM ION, Transthyretin 著者 Mizuguchi, M, Yamada, S, Obita, T. 登録日 2023-06-07 公開日 2024-04-17 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Trypsin-induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis. Febs J., 291, 2024
8JSC	Structure of the FSP1 protein from Human 分子名称: 6-HYDROXY-FLAVIN-ADENINE DINUCLEOTIDE, Ferroptosis suppressor protein 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Zhang, S.T, Jia, D. 登録日 2023-06-19 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 FSP1 oxidizes NADPH to suppress ferroptosis. Cell Res., 33, 2023
7DDE	Cryo-EM structure of the Ape4 and Nbr1 complex 分子名称: Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION 著者 Zhang, J, Ye, K. 登録日 2020-10-28 公開日 2021-07-14 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.26 Å) 主引用文献 Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1. Embo J., 40, 2021
8UQ3	Structure of human RyR2-S2808D in the closed state in the presence of ARM210 分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-10-23 公開日 2023-11-15 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024
8KIF	The structure of MmaE with substrate 分子名称: (3R)-3-(2-hydroxy-2-oxoethylamino)decanoic acid, FE (II) ION, Putative dioxygenase 著者 Chen, J, Zhou, J. 登録日 2023-08-23 公開日 2024-04-17 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Variation in biosynthesis and metal-binding properties of isonitrile-containing peptides produced by Mycobacteria versus Streptomyces. Acs Catalysis, 14, 2024
8UQ4	Structure of human RyR2-S2808D in the subprimed state in the presence of H2O2/NOC-12/GSH 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-10-23 公開日 2023-11-15 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024
8GTG	Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-I-152 by XFEL 分子名称: 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N},~{N}-bis(2-methoxyethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 著者 Cho, H.S, Kim, H. 登録日 2022-09-08 公開日 2023-09-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
8JQY	Crystal Structure of nucleotide-free mIRGB10 分子名称: Immunity-related GTPase family member b10 著者 Ha, H.J, Park, H.H. 登録日 2023-06-15 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.68 Å) 主引用文献 Structural basis of IRGB10 oligomerization by GTP hydrolysis. Front Immunol, 14, 2023
8UXC	Structure of PKA phosphorylated human RyR2-R420Q in the primed state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024
7DD9	Cryo-EM structure of the Ams1 and Nbr1 complex 分子名称: Alpha-mannosidase,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION 著者 Zhang, J, Ye, K. 登録日 2020-10-28 公開日 2021-07-14 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1. Embo J., 40, 2021
8GCV	XFEL structure of Mycobacterium tuberculosis beta lactamase microcrystals 分子名称: Beta-lactamase, PHOSPHATE ION 著者 Malla, T.N, Schmidt, M. 登録日 2023-03-03 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Heterogeneity in M. tuberculosis beta-lactamase inhibition by Sulbactam. Nat Commun, 14, 2023
8GCT	XFEL structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for 6 ms 分子名称: Beta-lactamase, PHOSPHATE ION 著者 Malla, T.N, Schmidt, M. 登録日 2023-03-03 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Heterogeneity in M. tuberculosis beta-lactamase inhibition by Sulbactam. Nat Commun, 14, 2023
8GCS	XFEL structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for 3 ms 分子名称: Beta-lactamase, PHOSPHATE ION 著者 Malla, T.N, Schmidt, M. 登録日 2023-03-03 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Heterogeneity in M. tuberculosis beta-lactamase inhibition by Sulbactam. Nat Commun, 14, 2023
8JP6	Cryo-EM structures of the head region of full-length ERGIC-53 with MCFD2 (Substate A) 分子名称: CALCIUM ION, Multiple coagulation factor deficiency protein 2, Protein ERGIC-53, ... 著者 Watanabe, S, Inaba, K. 登録日 2023-06-10 公開日 2024-04-17 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 Structure of full-length ERGIC-53 in complex with MCFD2 for cargo transport. Nat Commun, 15, 2024
8UQ2	Structure of human RyR2-S2808D in the subprimed state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-10-23 公開日 2023-11-15 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024
8GCX	XFEL structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for 700 ms 分子名称: Beta-lactamase, PHOSPHATE ION, TRANS-ENAMINE INTERMEDIATE OF SULBACTAM 著者 Malla, T.N, Schmidt, M. 登録日 2023-03-03 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Heterogeneity in M. tuberculosis beta-lactamase inhibition by Sulbactam. Nat Commun, 14, 2023
8UXE	Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210 分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024
8GKR	Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA 分子名称: 2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate), CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... 著者 Jung, H. 登録日 2023-03-20 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.784 Å) 主引用文献 Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA To Be Published
8GML	Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dG 分子名称: 2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate), CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... 著者 Jung, H. 登録日 2023-03-26 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.567 Å) 主引用文献 Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA To Be Published

<1351135213531354135513561357135813591360136113621363136413651366>