PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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2JEF	The Molecular Basis of Selectivity of Nucleotide Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state and X-Ray Crystallography of Correct and Incorrect Pairing 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*DOC)-3', 5'-D(*TP*CP*AP*CP*BZGP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP CP*CP*C)-3', ... 著者 Eoff, R.L, Angel, K.C, Kosekov, I.D, Egli, M, Guengerich, F.P. 登録日 2007-01-17 公開日 2007-03-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus Solfataricus DNA Polymerase Dpo4: Steady-State and Pre-Steady-State Kinetics and X-Ray Crystallography of Correct and Incorrect Pairing. J.Biol.Chem., 282, 2007
4G94	G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex 分子名称: ORF067, RNA polymerase sigma factor rpoD 著者 Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A. 登録日 2012-07-23 公開日 2013-01-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9971 Å) 主引用文献 Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein. Cell(Cambridge,Mass.), 151, 2012
1O0B	CRYSTAL STRUCTURE OF L-GLUTAMINE AND AMPCPP BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE 分子名称: ADENOSINE MONOPHOSPHATE, GLUTAMINE, Glutaminyl tRNA, ... 著者 Bullock, T.L, Perona, J.J. 登録日 2003-02-20 公開日 2003-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Amino Acid Discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants J.Mol.Biol., 328, 2003
5IF8	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine 分子名称: 1,2-ETHANEDIOL, 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
5IFB	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4719 5-chloro-2-(1H-imidazol-1-yl)aniline 分子名称: 5-chloro-2-(1H-imidazol-1-yl)aniline, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
5IF7	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-279 N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 分子名称: DIMETHYL SULFOXIDE, N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Polymerase acidic protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
5O7T	Crystal structure of KlenTaq mutant M747K in a closed ternary complex with a dG:dCTP base pair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase I, thermostable, ... 著者 Betz, K, Diederichs, K, Marx, A. 登録日 2017-06-09 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for the selective incorporation of an artificial nucleotide opposite a DNA adduct by a DNA polymerase. Chem. Commun. (Camb.), 53, 2017
7JMN	Tail module of Mediator complex 分子名称: MED15, Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 16, ... 著者 Zhang, H.Q, Chen, D.C. 登録日 2020-08-02 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Mediator structure and conformation change. Mol.Cell, 81, 2021
4H5O	Crystal Structure of Rift Valley Fever Virus Nucleocapsid Protein Pentamer Bound to Single-stranded RNA 分子名称: 35-mer poly(U) RNA, Nucleocapsid protein 著者 Raymond, D.D, Smith, J.L. 登録日 2012-09-18 公開日 2012-11-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Phleboviruses encapsidate their genomes by sequestering RNA bases. Proc.Natl.Acad.Sci.USA, 109, 2012
5IF5	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to EBSI-39 (2,3-dichlorophenyl)methanol 分子名称: (2,3-dichlorophenyl)methanol, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-03-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
2JEJ	The Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state Kinetics and X- Ray Crystallography of Correct and Incorrect Pairing 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*CP*G)-3', 5'-D(*TP*CP*AP*C BZGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... 著者 Eoff, R.L, Angel, K.C, Kosekov, I.D, Egli, M, Guengerich, F.P. 登録日 2007-01-17 公開日 2007-03-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus Solfataricus DNA Polymerase Dpo4: Steady-State and Pre-Steady-State Kinetics and X-Ray Crystallography of Correct and Incorrect Pairing. J.Biol.Chem., 282, 2007
5IFC	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole 分子名称: 1-(4-bromophenyl)-1H-imidazole, DIMETHYL SULFOXIDE, Polymerase acidic protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
7KPW	Structure of the H-lobe of yeast CKM 分子名称: Mediator of RNA polymerase II transcription subunit 12 著者 Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. 登録日 2020-11-12 公開日 2021-01-27 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
4H5P	Crystal Structure of Rift Valley Fever Virus Nucleocapsid Protein Tetramer Bound to Single-stranded RNA 分子名称: 28-mer poly(U) RNA, Nucleocapsid protein 著者 Raymond, D.D, Smith, J.L. 登録日 2012-09-18 公開日 2012-11-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Phleboviruses encapsidate their genomes by sequestering RNA bases. Proc.Natl.Acad.Sci.USA, 109, 2012
8UMW	Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex in the five-subunit binding state (state 4) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, DNA (20-MER), ... 著者 Wang, F, He, Q, Li, H. 登録日 2023-10-18 公開日 2024-05-08 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC. Proc.Natl.Acad.Sci.USA, 121, 2024
1TV9	HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA CONTAINING A MISMATCHED TEMPLATE ADENINE AND INCOMING CYTIDINE 分子名称: 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Krahn, J.M, Beard, W.M, Wilson, S.H. 登録日 2004-06-29 公開日 2004-11-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 STRUCTURAL INSIGHTS INTO DNA POLYMERASE BETA DETERRENTS FOR MISINCORPORATION SUPPORT OF AN INDUCED-FIT MECHANISM FOR FIDELITY Structure, 12, 2004
3RMA	Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol 分子名称: DNA (5'-D(*CP*GP*AP*(CTG)*GP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*CP*A)-3'), DNA polymerase 著者 Aller, P, Duclos, S, Wallace, S.S, Doublie, S. 登録日 2011-04-20 公開日 2011-08-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 A crystallographic study of the role of sequence context in thymine glycol bypass by a replicative DNA polymerase serendipitously sheds light on the exonuclease complex. J.Mol.Biol., 412, 2011
1X9M	T7 DNA polymerase in complex with an N-2-acetylaminofluorene-adducted DNA 分子名称: 5'-D(*CP*CP*CP*(8FG)P*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*TP*GP*GP*TP*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', DNA polymerase, ... 著者 Dutta, S, Li, Y, Johnson, D, Dzantiev, L, Richardson, C.C, Romano, L.J, Ellenberger, T. 登録日 2004-08-23 公開日 2004-10-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Proc.Natl.Acad.Sci.USA, 101, 2004
4G6D	G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex 分子名称: ORF067, RNA polymerase sigma factor rpoD 著者 Darst, S.A, Osmundson, J.S. 登録日 2012-07-18 公開日 2013-01-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9971 Å) 主引用文献 Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein. Cell(Cambridge,Mass.), 151, 2012
6UOM	Y271G DNA polymerase beta ternary complex with templating adenine and incoming r8-oxo-GTP 分子名称: 1,2-ETHANEDIOL, 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Smith, M.R, Freudenthal, B.D. 登録日 2019-10-15 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase beta. J.Biol.Chem., 295, 2020
2A9L	SOLUTION NMR STRUCTURE OF A SUBSTRATE FOR THE ARCHAEAL PRE-TRNA SPLICING ENDONUCLEASES: THE BULGE-HELIX-BULGE MOTIF, MINIMIZED AVERAGE STRUCTURE 分子名称: ABISS7 RNA 著者 Diener, J.L, Moore, P.B. 登録日 1998-04-07 公開日 1998-06-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of a substrate for the archaeal pre-tRNA splicing endonucleases: the bulge-helix-bulge motif. Mol.Cell, 1, 1998
3MR5	Human DNA polymerase eta - DNA ternary complex with a CPD 1bp upstream of the active site (TT3) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*CP*GP*TP*CP*AP*TP*AP*A)-3'), DNA (5'-D(*TP*AP*AP*CP*(TTD)P*AP*TP*GP*AP*CP*GP*A)-3'), ... 著者 Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. 登録日 2010-04-28 公開日 2010-06-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
3MR3	Human DNA polymerase eta - DNA ternary complex with the 3'T of a CPD in the active site (TT1) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*(TTD)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*CP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. 登録日 2010-04-28 公開日 2010-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
3MR6	Human DNA polymerase eta - DNA ternary complex with a CPD 2bp upstream of the active site (TT4) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*C*AP*TP*CP*AP*(TTD)P*AP*CP*GP*AP*GP*C)-3'), DNA (5'-D(*TP*CP*TP*CP*GP*TP*AP*AP*T)-3'), ... 著者 Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. 登録日 2010-04-28 公開日 2010-06-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
6FBI	KlenTaq DNA polymerase in a closed, ternary complex with dGpNHpp bound in the active site 分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Kropp, H.M, Diederichs, K, Marx, A. 登録日 2017-12-19 公開日 2018-09-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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