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1W79
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Crystal structure of the DD-transpeptidase-carboxypeptidase from Actinomadura R39
分子名称: D-alanyl-D-alanine carboxypeptidase, MAGNESIUM ION, SULFATE ION
著者Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P.
登録日2004-08-31
公開日2005-06-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins.
J. Biol. Chem., 280, 2005
8TCJ
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Apo crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2)
分子名称: p51 subunit
著者Pedersen, L.C, London, R.E.
登録日2023-07-02
公開日2024-07-17
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献Apo crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2)
To Be Published
8TCM
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Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC1) with picric acid and Xanthene-1,3,6,8-tetrol bound
分子名称: 9H-xanthene-1,3,6,8-tetrol, PICRIC ACID, p51 subunit
著者Pedersen, L.C, London, R.E.
登録日2023-07-02
公開日2024-07-17
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC1) with picric acid and xanthene bound
To Be Published
8TIA
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CryoEM structure of locally-refined tetramer of Shedu nuclease domain from Bacillus cereus
分子名称: Shedu protein SduA
著者Gu, Y, Corbett, K.
登録日2023-07-19
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献Shedu anti-phage nucleases share a common enzymatic core regulated by diverse sensor domains
to be published
8TI8
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CryoEM structure of Shedu from Bacillus cereus
分子名称: Shedu protein SduA
著者Gu, Y, Corbett, K.
登録日2023-07-19
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Shedu anti-phage nucleases share a common enzymatic core regulated by diverse sensor domains
to be published
8TI9
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CryoEM structure of octamer assembly of Shedu nuclease domain from Bacillus cereus
分子名称: Shedu protein SduA
著者Gu, Y, Corbett, K.
登録日2023-07-19
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Shedu anti-phage nucleases share a common enzymatic core regulated by diverse sensor domains
to be published
1GSV
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Crystal structure of the P65 crystal form of photoactive yellow protein G47S mutant
分子名称: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
著者Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
登録日2002-01-08
公開日2002-02-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
8TCL
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Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2) with picrate bound
分子名称: PICRIC ACID, p51 subunit
著者Pedersen, L.C, London, R.E.
登録日2023-07-02
公開日2024-07-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Apo crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2)
To Be Published
8A51
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Crystal structure of HSF2BP-BRME1 complex
分子名称: 1,2-ETHANEDIOL, Break repair meiotic recombinase recruitment factor 1, CHLORIDE ION, ...
著者Miron, S, Legrand, P, Ropars, V, Ghouil, R, Zinn-Justin, S.
登録日2022-06-13
公開日2023-07-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination.
Sci Adv, 9, 2023
2W0X
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FACTOR INHIBITING HIF-1 ALPHA WITH PYRIDINE 2,4 DICARBOXYLIC ACID
分子名称: FE (II) ION, GLYCEROL, HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR, ...
著者Conejo-Garcia, A, Lienard, B.M.R, Clifton, I.J, McDonough, M.A, Schofield, C.J.
登録日2008-10-10
公開日2009-11-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor.
Bioorg. Med. Chem. Lett., 20, 2010
1VPO
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Crystal Structure Analysis of the Anti-testosterone Fab in Complex with Testosterone
分子名称: TESTOSTERONE, anti-testosterone (heavy chain), anti-testosterone (light chain)
著者Valjakka, J.M, Hemminki, A, Niemi, S, Soderlund, H, Takkinen, K, Rouvinen, J.
登録日2004-11-15
公開日2004-11-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone Fab in Complex with Testosterone. IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS
J.Biol.Chem., 277, 2002
1VJ9
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Urokinase Plasminogen Activator B-Chain-JT464 Complex
分子名称: N-(BENZYLSULFONYL)-L-SERYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}-O-BENZYL-L-SERINAMIDE, SULFATE ION, plasminogen activator, ...
著者Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J.
登録日2004-02-03
公開日2004-06-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
J.Biol.Chem., 279, 2004
1VQP
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The structure of the transition state analogue "RAP" bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*(DC)P*(DC)P*(PPU)*(LOF)P*(PO2)P*AP*C*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1H2K
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Factor Inhibiting HIF-1 alpha in complex with HIF-1 alpha fragment peptide
分子名称: FACTOR INHIBITING HIF1, FE (II) ION, HYPOXIA-INDUCIBLE FACTOR 1 ALPHA, ...
著者Elkins, J.M, Hewitson, K.S, McNeill, L.A, Schlemminger, I, Seibel, J.F, Schofield, C.J.
登録日2002-08-12
公開日2002-11-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of Factor-Inhibiting Hypoxia-Inducible Factor (Hif) Reveals Mechanism of Oxidative Modification of Hif-1Alpha
J.Biol.Chem., 278, 2003
2VPK
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Crystal structure of the BTB domain of human myoneurin
分子名称: MYONEURIN
著者Cooper, C.D.O, Murray, J.W, Bullock, A, Pike, A.C.W, von Delft, F, Filippakopoulos, P, Salah, E, Edwards, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Knapp, S.
登録日2008-02-29
公開日2008-03-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Btb Domain of Human Myoneurin
To be Published
8A8F
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Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2
分子名称: MANGANESE (II) ION, PHOSPHATE ION, RNA end formation protein 2, ...
著者Carminati, M, Manav, C.M, Bellini, D, Passmore, L.A.
登録日2022-06-22
公開日2023-11-29
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A direct interaction between CPF and RNA Pol II links RNA 3' end processing to transcription.
Mol.Cell, 83, 2023
1H2M
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Factor Inhibiting HIF-1 alpha in complex with HIF-1 alpha fragment peptide
分子名称: FACTOR INHIBITING HIF1, HYPOXIA-INDUCIBLE FACTOR 1 ALPHA, N-OXALYLGLYCINE, ...
著者Elkins, J.M, Hewitson, K.S, McNeill, L.A, Schlemminger, I, Seibel, J.F, Schofield, C.J.
登録日2002-08-12
公開日2002-11-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Factor-Inhibiting Hypoxia-Inducible Factor (Hif) Reveals Mechanism of Oxidative Modification of Hif-1Alpha
J.Biol.Chem., 278, 2003
1W10
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Urokinase type plasminogen activator
分子名称: N-(ISOBUTOXYCARBONYL)-D-SERYL-N-((1S)-4-{[AMINO(IMINO)METHYL]AMINO}-1-FORMYLBUTYL)-L-ALANINAMIDE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR
著者Jacob, U.
登録日2004-06-15
公開日2008-05-20
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors.
J.Mol.Biol., 328, 2003
2X0L
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Crystal structure of a neuro-specific splicing variant of human histone lysine demethylase LSD1.
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, HISTONE H3 PEPTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
著者Zibetti, C, Adamo, A, Binda, C, Forneris, F, Verpelli, C, Ginelli, E, Mattevi, A, Sala, C, Battaglioli, E.
登録日2009-12-15
公開日2010-03-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Alternative Splicing of the Histone Demethylase Lsd1/Kdm1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System.
J.Neurosci., 30, 2010
1VQM
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The structure of the transition state analogue "DAN" bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)P*(PO2)P*(DA)P*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1W12
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UROKINASE TYPE PLASMINOGEN ACTIVATOR
分子名称: N-((1S)-4-{[AMINO(IMINO)METHYL]AMINO}-1-FORMYLBUTYL)-2-{(3R)-3-[(BENZYLSULFONYL)AMINO]-2-OXO-5-PHENYL-2,3-DIHYDRO-1H-1,4-BENZODIAZEPIN-1-YL}ACETAMIDE, UROKINASE-TYPE PLASMINOGEN ACTIVATOR
著者Jacob, U.
登録日2004-06-15
公開日2008-05-20
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystals of Urokinase Type Plasminogen Activator Complexes Reveal the Binding Mode of Peptidomimetic Inhibitors.
J.Mol.Biol., 328, 2003
1VSO
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Crystal Structure of the Ligand-Binding Core of iGluR5 in Complex With the Antagonist (S)-ATPO at 1.85 A resolution
分子名称: (S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACID, GLYCEROL, Glutamate receptor, ...
著者Hald, H, Naur, P, Gajhede, M, Kastrup, J.S.
登録日2007-03-29
公開日2007-07-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
J.Biol.Chem., 282, 2007
2X35
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Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1.
分子名称: PEREGRIN
著者Vezzoli, A, Bonadies, N, Allen, M.D, Freund, S.M.V, Santiveri, C.M, Kvinlaug, B, Huntly, B.J.P, Gottgens, B, Bycroft, M.
登録日2010-01-21
公開日2010-02-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
1W0Z
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Urokinase type plasminogen activator
分子名称: N-(BUTYLSULFONYL)-D-SERYL-N-{4-[AMINO(IMINO)METHYL]BENZYL}-L-ALANINAMIDE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR
著者Jacob, U.
登録日2004-06-15
公開日2008-05-20
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors.
J.Mol.Biol., 328, 2003
1VQ9
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The structure of CCA-PHE-CAP-BIO and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*AP*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005

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