PDB: 97814 件ウェブページステータス検索Chemie searchBIRD

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4K4R	TL-3 inhibited Trp6Ala HIV Protease with 1-bromo-2-napthoic acid bound in exosite 分子名称: 1-bromonaphthalene-2-carboxylic acid, BROMIDE ION, DIMETHYL SULFOXIDE, ... 著者 Tiefenbrunn, T, Stout, C.D. 登録日 2013-04-12 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic Fragment-Based Drug Discovery: Use of a Brominated Fragment Library Targeting HIV Protease. Chem.Biol.Drug Des., 83, 2014
5GIH	Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-phenylethylamine 分子名称: COENZYME A, Dopamine N-acetyltransferase, N-(2-phenylethyl)acetamide 著者 Yang, Y.C, Wu, C.Y, Cheng, H.C, Lyu, P.C. 登録日 2016-06-23 公開日 2017-07-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.392 Å) 主引用文献 Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-phenylethylamine To Be Published
3KMY	Structure of BACE bound to SCH12472 分子名称: 3-[2-(3-chlorophenyl)ethyl]pyridin-2-amine, Beta-secretase 1 著者 Strickland, C, Wang, Y. 登録日 2009-11-11 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel muM Leads for the Development of nM BACE-1 (beta-Site APP Cleaving Enzyme 1) Inhibitors. J.Med.Chem., 53, 2010
5HUP	Crystal Structure of NadC from Streptococcus pyogenes 分子名称: Nicotinate-nucleotide pyrophosphorylase (Carboxylating), SULFATE ION 著者 Booth, W.T, Chruszcz, M. 登録日 2016-01-27 公開日 2017-01-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 Streptococcus pyogenes quinolinate-salvage pathway-structural and functional studies of quinolinate phosphoribosyl transferase and NH3 -dependent NAD(+) synthetase. FEBS J., 284, 2017
3KMX	Structure of BACE bound to SCH346572 分子名称: 4-butoxy-3-chlorobenzyl imidothiocarbamate, Beta-secretase 1 著者 Strickland, C, Wang, Y. 登録日 2009-11-11 公開日 2010-01-19 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel muM Leads for the Development of nM BACE-1 (beta-Site APP Cleaving Enzyme 1) Inhibitors. J.Med.Chem., 53, 2010
3KN0	Structure of BACE bound to SCH708236 分子名称: 3-[2-(3-{[(furan-2-ylmethyl)(methyl)amino]methyl}phenyl)ethyl]pyridin-2-amine, Beta-secretase 1, L(+)-TARTARIC ACID 著者 Strickland, C, Wang, Y. 登録日 2009-11-11 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel muM Leads for the Development of nM BACE-1 (beta-Site APP Cleaving Enzyme 1) Inhibitors. J.Med.Chem., 53, 2010
5FHQ	Crystal structure of (WT) Rat Catechol-O-Methyltransferase in complex with AdoMet and 3,5-dinitrocatechol (DNC) 分子名称: 3,5-DINITROCATECHOL, Catechol O-methyltransferase, MAGNESIUM ION, ... 著者 Levy, C. 登録日 2015-12-22 公開日 2016-02-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Effects of Active-Site Modification and Quaternary Structure on the Regioselectivity of Catechol-O-Methyltransferase. Angew.Chem.Int.Ed.Engl., 55, 2016
3MNP	Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, V708A, E711G) mutations at 1.50A 分子名称: DEXAMETHASONE, GLYCEROL, Glucocorticoid receptor, ... 著者 Schoch, G.A, Seitz, T, Benz, J, Banner, D, Stihle, M, D'Arcy, B, Thoma, R, Sterner, R, Hennig, M, Ruf, A. 登録日 2010-04-22 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening. J.Mol.Biol., 403, 2010
3MNE	Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by F608S mutation at 1.96A 分子名称: DEXAMETHASONE, GLYCEROL, Glucocorticoid receptor, ... 著者 Schoch, G.A, Seitz, T, Benz, J, Banner, D, Stihle, M, D'Arcy, B, Thoma, R, Sterner, R, Hennig, M, Ruf, A. 登録日 2010-04-21 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening. J.Mol.Biol., 403, 2010
1C02	CRYSTAL STRUCTURE OF YEAST YPD1P 分子名称: PHOSPHOTRANSFERASE YPD1P 著者 Song, H.K, Lee, J.Y, Lee, M.G, Suh, S.W. 登録日 1999-07-14 公開日 2000-01-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Insights into eukaryotic multistep phosphorelay signal transduction revealed by the crystal structure of Ypd1p from Saccharomyces cerevisiae. J.Mol.Biol., 293, 1999
3M8E	Protein structure of Type III plasmid segregation TubR 分子名称: Putative DNA-binding protein 著者 Ni, L, Schumacher, M.A. 登録日 2010-03-17 公開日 2010-07-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. Proc.Natl.Acad.Sci.USA, 107, 2010
1NQA	Glyceraldehyde-3-Phosphate Dehydrogenase Mutant With Cys 149 Replaced By Ala Complexed With Nad+ and D-Glyceraldehyde-3-Phosphate 分子名称: GLYCERALDEHYDE-3-PHOSPHATE, Glyceraldehyde 3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Didierjean, C, Corbier, C, Fatih, M, Favier, F, Boschi-Muller, S, Branlant, G, Aubry, A. 登録日 2003-01-21 公開日 2003-04-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of two ternary complexes of phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase from Bacillus stearothermophilus with NAD and D-Glyceraldehyde-3-Phosphate J.Biol.Chem., 278, 2003
5DQ0	Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Tsai, Y.I, Rana, R.R, Zachary, I, Djordjevic, S. 登録日 2015-09-14 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site To Be Published
3M8K	Protein structure of type III plasmid segregation TubZ 分子名称: FtsZ/tubulin-related protein 著者 Schumacher, M.A, Ni, L. 登録日 2010-03-18 公開日 2010-07-07 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. Proc.Natl.Acad.Sci.USA, 107, 2010
3M89	Structure of TubZ-GTP-g-S 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, FtsZ/tubulin-related protein 著者 Ni, L, Xu, W, Schumacher, M.A. 登録日 2010-03-17 公開日 2010-07-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. Proc.Natl.Acad.Sci.USA, 107, 2010
3M8F	Protein structure of type III plasmid segregation TubR mutant 分子名称: Putative DNA-binding protein 著者 Schumacher, M.A, Ni, L. 登録日 2010-03-17 公開日 2010-07-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. Proc.Natl.Acad.Sci.USA, 107, 2010
7CVN	The N-arylsulfonyl-indole-2-carboxamide-based inhibitors against fructose-1,6-bisphosphatase 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 4-(3-acetamidophenyl)-N-(4-methoxyphenyl)sulfonyl-7-nitro-1H-indole-2-carboxamide, Fructose-1,6-bisphosphatase 1 著者 Wang, X, Zhou, J, Xu, B. 登録日 2020-08-26 公開日 2020-09-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Design,synthesis,biological evaluation and binding mode analysis of 7-nitro-indole-N-acylarylsulfonamide-based fructose-1,6-bisphosphatase inhibitors Chinese journal of medicinal chemistry, 30, 2020
4K4P	TL-3 inhibited Trp6Ala HIV Protease 分子名称: HIV-1 protease, NITRATE ION, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate 著者 Tiefenbrunn, T, Stout, C.D. 登録日 2013-04-12 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystallographic Fragment-Based Drug Discovery: Use of a Brominated Fragment Library Targeting HIV Protease. Chem.Biol.Drug Des., 83, 2014
1OFI	Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae) 分子名称: 4-IODO-3-NITROPHENYL ACETYL-LEUCINYL-LEUCINYL-LEUCINYL-VINYLSULFONE, ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ... 著者 Kwon, A.R, Kessler, B.M, Overkleeft, H.S, McKay, D.B. 登録日 2003-04-14 公開日 2003-07-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure and Reactivity of an Asymmetric Complex between Hslv and I-Domain Deleted Hslu, a Prokaryotic Homolog of the Eukaryotic Proteasome J.Mol.Biol., 330, 2003
1NQ5	Glyceraldehyde-3-Phosphate Dehydrogenase Mutant With Cys 149 Replaced By Ser Complexed With Nad+ 分子名称: Glyceraldehyde 3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION 著者 Didierjean, C, Corbier, C, Fatih, M, Favier, F, Boschi-Muller, S, Branlant, G, Aubry, A. 登録日 2003-01-21 公開日 2003-04-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystal structure of two ternary complexes of phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase from Bacillus stearothermophilus with NAD and D-Glyceraldehyde-3-Phosphate J.Biol.Chem., 278, 2003
1NPT	Glyceraldehyde-3-Phosphate Dehydrogenase Mutant With Cys 149 replaced by Ala complexed with NAD+ 分子名称: Glyceraldehyde 3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION 著者 Didierjean, C, Corbier, C, Fatih, M, Favier, F, Boschi-Muller, S, Branlant, G, Aubry, A. 登録日 2003-01-20 公開日 2003-04-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Crystal structure of two ternary complexes of phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase from Bacillus stearothermophilus with NAD and D-Glyceraldehyde-3-Phosphate J.Biol.Chem., 278, 2003
1OFH	Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV, ... 著者 Kwon, A.R, Kessler, B.M, Overkleeft, H.S, McKay, D.B. 登録日 2003-04-14 公開日 2003-07-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure and Reactivity of an Asymmetric Complex between Hslv and I-Domain Deleted Hslu, a Prokaryotic Homolog of the Eukaryotic Proteasome J.Mol.Biol., 330, 2003
3TGR	Crystal structure of unliganded HIV-1 clade C strain C1086 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 clade C1086 gp120 著者 Kwon, Y.D, Kwong, P.D. 登録日 2011-08-17 公開日 2012-04-04 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc.Natl.Acad.Sci.USA, 109, 2012
1K58	Crystal Structure of Human Angiogenin Variant D116H 分子名称: Angiogenin 著者 Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. 登録日 2001-10-10 公開日 2002-03-20 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Biochemistry, 41, 2002
3TGT	Crystal structure of unliganded HIV-1 clade A/E strain 93TH057 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 clade A/E 93TH057 gp120 著者 Kwon, Y.D, Kwong, P.D. 登録日 2011-08-17 公開日 2012-04-04 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc.Natl.Acad.Sci.USA, 109, 2012

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