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8RJL
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BU of 8rjl by Molmil
Structure of a first order Sierpinski triangle formed by the H369R mutant of the citrate synthase from Synechococcus elongatus
分子名称: Citrate synthase
著者Lo, Y.K, Bohn, S, Sendker, F.L, Schuller, J.M, Hochberg, G.
登録日2023-12-21
公開日2024-02-28
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Emergence of fractal geometries in the evolution of a metabolic enzyme.
Nature, 628, 2024
7K81
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BU of 7k81 by Molmil
KIR3DL1*005 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, Beta-2-microglobulin, ...
著者MacLachlan, B.J, Rossjohn, J, Vivian, J.P.
登録日2020-09-24
公開日2020-12-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.
J Immunol., 206, 2021
7SPB
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BU of 7spb by Molmil
Models for C13 reconstruction of Outer Membrane Core Complex (OMCC) of Type IV Secretion System (T4SS) encoded by F-plasmid (pED208).
分子名称: TraB, TraK, TraV
著者Liu, X, Khara, P, Baker, M.L, Christie, P.J, Hu, B.
登録日2021-11-02
公開日2022-02-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Structure of a type IV secretion system core complex encoded by multi-drug resistance F plasmids
Nat Commun, 13, 2022
2OE8
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BU of 2oe8 by Molmil
1.8 A X-ray crystal structure of Apramycin complex with RNA fragment GGGCGUCGCUAGUACC/CGGUACUAAAAGUCGCC containing the human ribosomal decoding A site: RNA construct with 5'-overhang
分子名称: APRAMYCIN, RNA (5'-R(*CP*GP*GP*UP*AP*CP*UP*AP*AP*AP*AP*GP*UP*CP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*C)-3')
著者Hermann, T, Tereshko, V, Skripkin, E, Patel, D.J.
登録日2006-12-28
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Apramycin recognition by the human ribosomal decoding site.
Blood Cells Mol.Dis., 38, 2007
7T7V
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BU of 7t7v by Molmil
Munc13-1 C1-C2B-MUN-C2C Lateral conformation on lipid bilayer surface
分子名称: Protein unc-13 homolog A
著者Grushin, K, Sindelar, C.V.
登録日2021-12-15
公開日2022-02-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release.
Proc.Natl.Acad.Sci.USA, 119, 2022
8RJK
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BU of 8rjk by Molmil
Pseudoatomic model of a second-order Sierpinski triangle formed by the citrate synthase from Synechococcus elongatus
分子名称: Citrate synthase
著者Lo, Y.K, Bohn, S, Sendker, F.L, Schuller, J.M, Hochberg, G.
登録日2023-12-21
公開日2024-02-28
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (5.91 Å)
主引用文献Emergence of fractal geometries in the evolution of a metabolic enzyme.
Nature, 628, 2024
6ZPH
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BU of 6zph by Molmil
Kinesin binding protein complexed with Kif15 motor domain
分子名称: ADENOSINE-5'-DIPHOSPHATE, KIF-binding protein, Kinesin-like protein KIF15, ...
著者Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A.
登録日2020-07-08
公開日2020-12-30
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献The mechanism of kinesin inhibition by kinesin-binding protein.
Elife, 9, 2020
2XRW
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BU of 2xrw by Molmil
Linear binding motifs for JNK and for calcineurin antagonistically control the nuclear shuttling of NFAT4
分子名称: GLYCEROL, MITOGEN-ACTIVATED PROTEIN KINASE 8, NUCLEAR FACTOR OF ACTIVATED T-CELLS, ...
著者Barkai, T, Toeoroe, I, Garai, A, Remenyi, A.
登録日2010-09-23
公開日2011-09-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove.
Sci. Signal, 5, 2012
6ZPK
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BU of 6zpk by Molmil
Crystal structure of the unconventional kinetochore protein Trypanosoma brucei KKT4 BRCT domain
分子名称: GLYCEROL, SULFATE ION, Trypanosoma brucei KKT4 463-645
著者Ludzia, P, Lowe, E.D, Marciano, G, Mohammed, S, Redfield, C, Akiyoshi, B.
登録日2020-07-08
公開日2020-10-21
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structural characterization of KKT4, an unconventional microtubule-binding kinetochore protein.
Structure, 29, 2021
8R2C
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BU of 8r2c by Molmil
Crystal structure of the Vint domain from Tetrahymena thermophila
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, von willebrand factor type A (VWA) domain was originally protein
著者Iwai, H, Beyer, H.M, Johannson, J.E, Li, M, Wlodawer, A.
登録日2023-11-03
公開日2024-02-28
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The three-dimensional structure of the Vint domain from Tetrahymena thermophila suggests a ligand-regulated cleavage mechanism by the HINT fold.
Febs Lett., 598, 2024
7SVS
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BU of 7svs by Molmil
Crystal structure analysis of the G73A mutant of Superoxide Dismutase from Trichoderma reesei
分子名称: MANGANESE (II) ION, Superoxide dismutase
著者Mendoza Rengifo, E, Ferreira Jr, J.R, Garratt, C.R.
登録日2021-11-19
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Unexpected plasticity of the quaternary structure of iron-manganese superoxide dismutases.
J.Struct.Biol., 214, 2022
7SPI
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BU of 7spi by Molmil
Models for C13 reconstruction of Outer Membrane Core Complex (OMCC) of Type IV Secretion System (T4SS) encoded by a plasmid overproducing TraV, TraK and TraB of pED208
分子名称: TraB, TraK, TraV
著者Liu, X, Khara, P, Baker, M.L, Christie, P.J, Hu, B.
登録日2021-11-02
公開日2022-02-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure of a type IV secretion system core complex encoded by multi-drug resistance F plasmids
Nat Commun, 13, 2022
3K97
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BU of 3k97 by Molmil
HSP90 N-terminal domain in complex with 4-chloro-6-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol
分子名称: 4-chloro-6-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol, DIMETHYL SULFOXIDE, Heat shock protein HSP 90-alpha
著者Gajiwala, K.S.
登録日2009-10-15
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone.
J.Med.Chem., 53, 2010
2XP8
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BU of 2xp8 by Molmil
DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION
分子名称: 4-(MORPHOLIN-4-YLCARBONYL)-2-PHENYL-1H-IMIDAZOLE-5-CARBOXYLIC ACID, DODECAETHYLENE GLYCOL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1
著者Potter, A, Oldfield, V, Nunns, C, Fromont, C, Ray, S, Northfield, C.J, Bryant, C.J, Scrace, S.F, Robinson, D, Matossova, N, Baker, L, Dokurno, P, Surgenor, A.E, Davis, B.E, Richardson, C.M, Murray, J.B, Moore, J.D.
登録日2010-08-25
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of Cell-Active Phenyl-Imidazole Pin1 Inhibitors by Structure-Guided Fragment Evolution.
Bioorg.Med.Chem.Lett., 20, 2010
6ZQJ
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BU of 6zqj by Molmil
Cryo-EM structure of trimeric prME spike of Spondweni virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, prM
著者Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M.
登録日2020-07-09
公開日2021-01-20
最終更新日2021-08-04
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.
Nat Commun, 12, 2021
6ZQP
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BU of 6zqp by Molmil
Structure of the Pmt2-MIR domain with bound ligands
分子名称: GLYCEROL, PMT2 isoform 1, SULFATE ION, ...
著者Wild, K, Chiapparino, A, Hackmann, Y, Mortensen, S, Sinning, I.
登録日2020-07-10
公開日2020-12-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Functional implications of MIR domains in protein O -mannosylation.
Elife, 9, 2020
5LCU
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BU of 5lcu by Molmil
Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with a S-methyl-piperazine substituted Fasudil-derivative (Ligand 01)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE, METHANOL, ...
著者Wienen-Schmidt, B, Heine, A, Klebe, G.
登録日2016-06-22
公開日2018-01-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.579 Å)
主引用文献Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with different Fasudil-derivatives
To Be Published
7TDB
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BU of 7tdb by Molmil
Crystal structure of the E. coli thiM riboswitch in complex with thiamine bisphosphonate, manganese ions
分子名称: MAGNESIUM ION, MANGANESE (II) ION, [2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-5-yl]ethoxy-oxidanyl-phosphoryl]methylphosphonic acid, ...
著者Nuthanakanti, A, Serganov, A.
登録日2021-12-30
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Subsite Ligand Recognition and Cooperativity in the TPP Riboswitch: Implications for Fragment-Linking in RNA Ligand Discovery.
Acs Chem.Biol., 17, 2022
5LDF
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BU of 5ldf by Molmil
Maltose binding protein genetically fused to dodecameric glutamine synthetase
分子名称: Glutamine synthetase, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Coscia, F, Petosa, C, Schoehn, G.
登録日2016-06-25
公開日2016-08-10
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein.
Sci Rep, 6, 2016
7TD7
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BU of 7td7 by Molmil
Crystal structure of an E. coli thiM riboswitch bound to thiamine, manganese ions
分子名称: 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Nuthanakanti, A, Serganov, A.
登録日2021-12-30
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Subsite Ligand Recognition and Cooperativity in the TPP Riboswitch: Implications for Fragment-Linking in RNA Ligand Discovery.
Acs Chem.Biol., 17, 2022
2O2B
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BU of 2o2b by Molmil
Spectroscopic and Structural Study of the Heterotropic Linkage between Halide and Proton Ion Binding to Gfp Proteins: E2(GFP)-I Complex
分子名称: Green fluorescent protein, IODIDE ION
著者Garau, G.
登録日2006-11-29
公開日2007-05-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Spectroscopic and Structural Study of Proton and Halide Ion Cooperative Binding to GFP.
Biophys.J., 93, 2007
3K9Y
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BU of 3k9y by Molmil
Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CYMAL-5
分子名称: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ...
著者Annalora, A.J, Goodin, D.B, Hong, W, Zhang, Q, Johnson, E.F, Stout, C.D.
登録日2009-10-16
公開日2009-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism.
J.Mol.Biol., 396, 2010
2OGM
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BU of 2ogm by Molmil
The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative SB-571519
分子名称: (2S,3AR,4R,5S,6S,8R,9R,9AR,10R)-2,5-DIHYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROP[1]ENOCYCLOPENTA[8]ANNULEN-8-YL [(6-AMINOPYRIDAZIN-3-YL)CARBONYL]CARBAMATE, 23S ribosomal RNA, 50S ribosomal protein L3
著者Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A.
登録日2007-01-07
公開日2007-05-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
7KA3
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BU of 7ka3 by Molmil
Aldolase, rabbit muscle (beam-tilt refinement x3)
分子名称: Fructose-bisphosphate aldolase A
著者Kearns, S.K, Cash, J.N, Cianfrocco, M.A, Li, Y.
登録日2020-09-29
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献High-resolution cryo-EM using beam-image shift at 200 keV.
Iucrj, 7, 2020
8R5X
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BU of 8r5x by Molmil
Structure of coxsackievirus B5 capsid (mutant CVB5F.cas.genogroupB) - F particle
分子名称: Coxsackievirus B5 (mutant CVB5F.cas.genogroupB) - VP1, PALMITIC ACID
著者Kumar, K, Antanasijevic, A.
登録日2023-11-18
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Influence of Amino Acid Substitutions in Capsid Proteins of Coxsackievirus B5 on Free Chlorine and Thermal Inactivation.
Environ Sci Technol., 58, 2024

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