PDB: 22592 件ウェブページステータス検索Chemie searchBIRD

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5SCV	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-889 分子名称: 6-ethyl-5-(4-{3-[3-(1H-tetrazol-5-yl)propyl]phenoxy}butoxy)pyrimidine-2,4-diamine, CHLORIDE ION, Dihydrofolate reductase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-889 to be published
5SCS	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-781 分子名称: 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-N-(propane-2-sulfonyl)propanamide, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-781 to be published
5SD5	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1230 分子名称: 1,2-ETHANEDIOL, 1-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}-4-methylphenyl)azetidine-3-carboxylic acid, Dihydrofolate reductase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1230 to be published
5SCZ	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1224 分子名称: (2E)-3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}pyridin-3-yl)prop-2-en-1-ol, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1224 to be published
2YPQ	3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with tryptophan and tyrosine bound 分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 Blackmore, N.J, Reichau, S, Jiao, W, Hutton, R.D, Baker, E.N, Jameson, G.B, Parker, E.J. 登録日 2012-10-31 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis. J.Mol.Biol., 425, 2013
5SCO	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-M7 分子名称: 2-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-N,N-dimethylethane-1-sulfonamide, BROMIDE ION, Dihydrofolate reductase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-M7 to be published
5SCM	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-22 分子名称: 1,2-ETHANEDIOL, Dihydrofolate reductase, IODIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-22 to be published
5SCX	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1190 (racemic mixture) 分子名称: (2R)-2-[(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3,3-difluoropropanoic acid, 1,2-ETHANEDIOL, Dihydrofolate reductase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1190 (racemic mixture) to be published
5SCR	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-735 分子名称: (2R)-3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-2-methylpropanoic acid, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-735 to be published
5SD4	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1218 分子名称: 1,2-ETHANEDIOL, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}pyridin-3-yl)prop-2-yn-1-ol, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1218 to be published
5SCN	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-25 分子名称: 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-N-(methanesulfonyl)propanamide, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-25 to be published
5SCP	Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-23 分子名称: 1,2-ETHANEDIOL, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanamide, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-12-20 公開日 2022-02-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-23 to be published
4OOK	Third Metal bound M.tuberculosis methionine aminopeptidase 分子名称: COBALT (II) ION, Methionine aminopeptidase 2, SODIUM ION 著者 Reddi, R, Addlagatta, A. 登録日 2014-02-03 公開日 2015-02-04 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
3SPT	Crystal structure of GlmU from Mycobacterium tuberculosis in complex with ACETYL COENZYME A and URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE 分子名称: ACETYL COENZYME *A, Bifunctional protein glmU, MAGNESIUM ION, ... 著者 Jagtap, P.A, Prakash, B. 登録日 2011-07-03 公開日 2012-08-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Structure of Mycobacterium tuberculosis GlmU in complex with Acetyl CoA to be published
3ST8	Crystal structure of GlmU from Mycobacterium tuberculosis in complex with COENZYME A, GLUCOSAMINE 1-PHOSPHATE and URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE 分子名称: 2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, Bifunctional protein glmU, COENZYME A, ... 著者 Jagtap, P.A, Prakash, B. 登録日 2011-07-09 公開日 2012-08-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Structure of Mycobacterium tuberculosis GlmU in complex with Acetyl CoA to be published
4M52	Structure of Mtb Lpd bound to SL827 分子名称: Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, N~2~-[(2-amino-5-bromopyridin-3-yl)sulfonyl]-N-(4-methoxyphenyl)-N~2~-methylglycinamide 著者 Lima, C.D. 登録日 2013-08-07 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase. Biochemistry, 52, 2013
3TFT	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, pre-reaction complex with a 3,6-dihydropyrid-2-one heterocycle inhibitor 分子名称: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, DIMETHYL SULFOXIDE, PYRIDOXAL-5'-PHOSPHATE 著者 Geders, T.W, Finzel, B.C. 登録日 2011-08-16 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Mechanism-based Inactivation by Aromatization of the Transaminase BioA Involved in Biotin Biosynthesis in Mycobaterium tuberculosis. J.Am.Chem.Soc., 133, 2011
3SGI	Crystal structure of DNA ligase A BRCT domain deleted mutant of Mycobacterium tuberculosis 分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase 著者 Kukshal, V, Ravishankar, R. 登録日 2011-06-15 公開日 2012-06-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal Structure of Domain deleted mutant of Mycobacterium tuberculosis NAD+ dependent DNA ligase capture the AMP cofactor in a new state To be Published
1W7Q	Feglymycin P65 crystal form 分子名称: 1,2-ETHANEDIOL, ETHANOL, FEGLYMYCIN 著者 Bunkoczi, G, Vertesy, L, Sheldrick, G.M. 登録日 2004-09-08 公開日 2005-03-08 最終更新日 2019-05-22 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 The Antiviral Antibiotic Feglymycin: First Direct Methods Solution of a 1000Plus Equal-Atom Structure Angew.Chem.Int.Ed.Engl., 44, 2005
1W7R	Feglymycin P64 crystal form 分子名称: CITRATE ANION, FEGLYMYCIN, ISOPROPYL ALCOHOL 著者 Bunkoczi, G, Vertesy, L, Sheldrick, G.M. 登録日 2004-09-08 公開日 2005-03-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The Antiviral Antibiotic Feglymycin: First Direct Methods Solution of a 1000Plus Equal-Atom Structure Angew.Chem.Int.Ed.Engl., 44, 2005
4O1G	MTB adenosine kinase in complex with gamma-Thio-ATP 分子名称: Adenosine kinase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, SODIUM ION 著者 Dostal, J, Brynda, J, Hocek, M, Pichova, I. 登録日 2013-12-15 公開日 2014-11-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides J.Med.Chem., 57, 2014
3RHS	Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis complexed with CoA 分子名称: COENZYME A, Phosphopantetheine adenylyltransferase 著者 Timofeev, V.I, Smirnova, E.A, Chupova, L.A, Esipov, R.S, Kuranova, I.P. 登録日 2011-04-12 公開日 2012-04-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Three-Dimensional Structure of Phosphopantetheine Adenylyltransferase from Mycobacterium Crystallography Reports, 57, 2012
4F6E	Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MANGANESE (II) ION, ... 著者 Sheng, Y, Cascio, D, Valentine, J.S. 登録日 2012-05-14 公開日 2013-06-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae to be published
3RFF	Phosphopantetheine adenylyltransferase from Mycobacterium Tuberculosis (1.76 A resolution) 分子名称: Phosphopantetheine adenylyltransferase 著者 Timofeev, V.I, Smirnova, E.A, Chupova, L.A, Esipov, R.S, Kuranova, I.P. 登録日 2011-04-06 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Three-Dimensional Structure of Phosphopantetheine Adenylyltransferase from Mycobacterium Tuberculosis in the Apo Form and in Complexes with Coenzyme A and D Crystallography Reports, 57, 2012
2FHH	Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with a peptidyl boronate inhibitor MLN-273 分子名称: (1R)-3-METHYL-1-{[N-(MORPHOLIN-4-YLCARBONYL)-3-(1-NAPHTHYL)-D-ALANYL]AMINO}BUTYLBORONIC ACID, 20S proteasome, alpha and beta subunits, ... 著者 Li, H. 登録日 2005-12-23 公開日 2006-02-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate. Mol.Microbiol., 59, 2006

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