PDB: 4080 件ウェブページステータス検索Chemie searchBIRD

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7M1Q	Human ABCA4 structure in complex with N-ret-PE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Retinal-specific phospholipid-transporting ATPase ABCA4, ... 著者 Scortecci, J.F, Van Petegem, F, Molday, R.S. 登録日 2021-03-14 公開日 2021-09-08 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease. Nat Commun, 12, 2021
1IY5	Solution structure of wild type OMSVP3 分子名称: OMSVP3 著者 Hemmi, H, Kumazaki, T, Yamazaki, T, Kojima, S, Yoshida, T, Kyogoku, Y, Katsu, M, Yokosawa, H, Miura, K, Kobayashi, Y. 登録日 2002-07-23 公開日 2003-03-11 最終更新日 2024-10-30 実験手法 SOLUTION NMR 主引用文献 Inhibitory Specificity Change of Ovomucoid Third Domain of the Silver Pheasant upon Introduction of an Engineered Cys14-Cys39 Bond BIOCHEMISTRY, 42, 2003
1IY6	Solution structure of OMSVP3 variant, P14C/N39C 分子名称: OMSVP3 著者 Hemmi, H, Kumazaki, T, Yamazaki, T, Kojima, S, Yoshida, T, Kyogoku, Y, Katsu, M, Yokosawa, H, Miura, K, Kobayashi, Y. 登録日 2002-07-23 公開日 2003-03-11 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Inhibitory Specificity Change of Ovomucoid Third Domain of the Silver Pheasant upon Introduction of an Engineered Cys14-Cys39 Bond BIOCHEMISTRY, 42, 2003
5TSW	HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT 分子名称: PROTEIN (TUMOR NECROSIS FACTOR-ALPHA) 著者 Cha, S.-S, Kim, J.-S, Cho, H.-S, Oh, B.-H. 登録日 1999-04-22 公開日 1999-05-07 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity. J.Biol.Chem., 273, 1998
5VAV	Design of a novel cyclic peptide that alleviates symptoms in a murine model of inflammatory bowel disease 分子名称: cyc-MC12 著者 Daly, N.L, Cobos Caceres, C. 登録日 2017-03-28 公開日 2017-05-10 最終更新日 2024-10-16 実験手法 SOLUTION NMR 主引用文献 An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease. J. Biol. Chem., 292, 2017
5VFW	An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease 分子名称: Annexin A1 著者 Daly, N.L, Cobos Caceres, C. 登録日 2017-04-09 公開日 2017-05-10 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease. J. Biol. Chem., 292, 2017
7KUS	Crystal Structure of Danio rerio Histone Deacetylase 10 H137A Mutant in Complex with N8-Acetylspermidine (Tetrahedral Intermediate) 分子名称: 1,2-ETHANEDIOL, 1-({4-[(3-aminopropyl)amino]butyl}amino)ethane-1,1-diol, DI(HYDROXYETHYL)ETHER, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2020-11-25 公開日 2021-02-03 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10. Biochemistry, 60, 2021
6CDX	High-resolution crystal structure of fluoropropylated cystine knot, binding to alpha-5 beta-6 integrin 分子名称: cystine knot (fluoropropylated) 著者 Kimura, R, Nix, J, Bongura, C, Chakraborti, S, Gambhir, S, Filipp, F.V. 登録日 2018-02-09 公開日 2019-08-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Evaluation of integrin alpha v beta6cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis. Nat Commun, 10, 2019
7KUQ	Crystal Structure of Danio rerio Histone Deacetylase 10 Y307F Mutant in Complex with N8-Acetylspermidine 分子名称: N-{4-[(3-aminopropyl)amino]butyl}acetamide, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2020-11-25 公開日 2021-02-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10. Biochemistry, 60, 2021
7KUR	Crystal Structure of Danio rerio Histone Deacetylase 10 Y307F Mutant in Complex with N-Acetylputrescine 分子名称: DI(HYDROXYETHYL)ETHER, N-(4-aminobutyl)acetamide, PHOSPHATE ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2020-11-25 公開日 2021-02-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10. Biochemistry, 60, 2021
7KUT	Crystal Structure of Danio rerio Histone Deacetylase 10 H137A Mutant in Complex with N-Acetylputrescine (Tetrahedral Intermediate) 分子名称: 1,2-ETHANEDIOL, 1-[(4-aminobutyl)amino]ethane-1,1-diol, DI(HYDROXYETHYL)ETHER, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2020-11-25 公開日 2021-02-03 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10. Biochemistry, 60, 2021
7KUV	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Acetate 分子名称: 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2020-11-25 公開日 2021-02-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10. Biochemistry, 60, 2021
5U87	NMR structure of the precursor protein PawS1 comprising SFTI-1 and a seed storage albumin 分子名称: Preproalbumin PawS1 著者 Franke, B, James, A.M, Mobli, M, Colgrave, M.L, Mylne, J.S, Rosengren, K.J. 登録日 2016-12-14 公開日 2017-03-01 最終更新日 2024-11-06 実験手法 SOLUTION NMR 主引用文献 NMR structure of the precursor protein PawS1 comprising SFTI-1 and a seed storage albumin to be published
7VOO	Induced alpha-2-macroglobulin monomer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... 著者 Huang, X, Wang, Y, Ping, Z. 登録日 2021-10-14 公開日 2022-10-19 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor. Sci China Life Sci, 65, 2022
7VON	Native alpha-2-macroglobulin monomer 分子名称: Alpha-2-macroglobulin 著者 Huang, X, Wang, Y. 登録日 2021-10-14 公開日 2022-11-16 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor. Sci China Life Sci, 65, 2022
8KF4	The cryo-EM structure of type1 amyloid beta 42 fibril in AD2 patient. 分子名称: Amyloid-beta precursor protein 著者 Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. 登録日 2023-08-15 公開日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 The cryo-EM structure of type1 amyloid beta 42 fibril in AD2 patient. To Be Published
8KEW	The cryo-EM structure of type1 amyloid beta 42 fibril. 分子名称: P3(40) 著者 Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. 登録日 2023-08-13 公開日 2024-08-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The cryo-EM structure of type1 amyloid beta 42 fibril. To Be Published
8KF1	The cryo-EM structure of AV-45 bound type1 amyloid beta 42 fibril. 分子名称: 4-[2-[6-[2-[2-(2-fluoranylethoxy)ethoxy]ethoxy]pyridin-3-yl]ethyl]-~{N}-methyl-aniline, P3(40) 著者 Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. 登録日 2023-08-15 公開日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The cryo-EM structure of AV-45 bound type1 amyloid beta 42 fibril. To Be Published
8KF5	The cryo-EM structure of type1 amyloid beta 42 fibril in AD3. 分子名称: Amyloid-beta precursor protein 著者 Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. 登録日 2023-08-15 公開日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 The cryo-EM structure of type1 amyloid beta 42 fibril in AD3. To Be Published
8KF3	The cryo-EM structure of type3 amyloid beta 42 fibril. 分子名称: Amyloid-beta precursor protein 著者 Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. 登録日 2023-08-15 公開日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The cryo-EM structure of type1 amyloid beta 42 fibril. To Be Published
8KF6	The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril. 分子名称: P3(40) 著者 Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. 登録日 2023-08-15 公開日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 The cryo-EM structure of type1 amyloid beta 42 fibril. To Be Published
8P4K	Vaccinia Virus palisade layer A10 trimer 分子名称: Core protein OPG136 著者 Datler, J, Hansen, J.M, Thader, A, Schloegl, A, Hodirnau, V.V, Schur, F.K.M. 登録日 2023-05-22 公開日 2024-01-17 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. Nat.Struct.Mol.Biol., 31, 2024
8OVB	Human Complement C3b in complex with Trypanosoma brucei ISG65. 分子名称: Complement C3, Complement C3f fragment, ISG65 G 著者 Cook, A.D, Higgins, M.K. 登録日 2023-04-25 公開日 2024-02-14 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular mechanism of complement inhibition by the trypanosome receptor ISG65. Elife, 12, 2024
8OTF	Ab typeII filament from Guam ALS/PDC 分子名称: Amyloid-beta precursor protein 著者 Qi, C, Yang, S, Scheres, S.H.W, Goedert, M. 登録日 2023-04-20 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023
8PE9	Complex between DDR1 DS-like domain and PRTH-101 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Liu, J, Chiang, H, Xiong, W, Laurent, V, Griffiths, S.C, Duelfer, J, Deng, H, Sun, X, Yin, Y.W, Li, W, Audoly, L.P, An, Z, Schuerpf, T, Li, R, Zhang, N. 登録日 2023-06-13 公開日 2023-06-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.152 Å) 主引用文献 A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer. J Immunother Cancer, 11, 2023

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