PDB: 12060 件ウェブページステータス検索Chemie searchBIRD

---

2ZNL	Crystal structure of PA-PB1 complex form influenza virus RNA polymerase 分子名称: Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit 著者 Obayashi, E, Yoshida, H, Kawai, F, Shibayama, N, Kawaguchi, A, Nagata, K, Tame, J.R.H, Park, S.-Y. 登録日 2008-04-28 公開日 2008-09-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structural basis for an essential subunit interaction in influenza virus RNA polymerase Nature, 454, 2008
7FDL	Crystal structure of transcription factor WER in complex with EGL3 分子名称: Transcription factor EGL1, Transcription factor WER 著者 Luo, Q, Wang, B. 登録日 2021-07-17 公開日 2022-07-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.897 Å) 主引用文献 Structural insights into partner selection for MYB and bHLH transcription factor complexes. Nat.Plants, 8, 2021
7FEW	Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cAMP-activated global transcriptional regulator Vfr 著者 Chew, B.L.A, Luo, D. 登録日 2021-07-22 公開日 2022-07-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr. Comput Struct Biotechnol J, 21, 2023
7FF0	Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GOLD ION, SULFATE ION, ... 著者 Chew, B.L.A, Luo, D. 登録日 2021-07-22 公開日 2022-07-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr. Comput Struct Biotechnol J, 21, 2023
2C8O	lysozyme (1sec) and UV lasr excited fluorescence 分子名称: LYSOZYME C 著者 Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. 登録日 2005-12-06 公開日 2006-03-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
7F6G	Cryo-EM structure of human angiotensin receptor AT1R in complex Gq proteins and Sar1-AngII 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin receptor AT1R, CHOLESTEROL, ... 著者 Zhang, D, Xu, L, Zhan, Y, Guo, J, Zhang, H. 登録日 2021-06-25 公開日 2023-03-29 最終更新日 2023-10-18 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural insights into angiotensin receptor signaling modulation by balanced and biased agonists. Embo J., 42, 2023
1B5T	ESCHERICHIA COLI METHYLENETETRAHYDROFOLATE REDUCTASE 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, MERCURY (II) ION, PROTEIN (METHYLENETETRAHYDROFOLATE REDUCTASE) 著者 Guenther, B.D, Sheppard, C.A, Tran, P, Rozen, R, Matthews, R.G, Ludwig, M.L. 登録日 1999-01-07 公開日 1999-01-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia. Nat.Struct.Biol., 6, 1999
2F6N	Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the free form 分子名称: ZINC ION, bromodomain PHD finger transcription factor 著者 Li, H, Patel, D.J. 登録日 2005-11-29 公開日 2006-07-11 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature, 442, 2006
1YV7	X-ray structure of (C87S,des103-104) onconase 分子名称: P-30 protein, SULFATE ION 著者 Merlino, A, Mazzarella, L, Carannante, A, Di Fiore, A, Di Donato, A, Notomista, E, Sica, F. 登録日 2005-02-15 公開日 2005-03-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Importance of Dynamic Effects on the Enzyme Activity: X-RAY STRUCTURE AND MOLECULAR DYNAMICS OF ONCONASE MUTANTS J.Biol.Chem., 280, 2005
3C7Q	Structure of VEGFR2 kinase domain in complex with BIBF1120 分子名称: SULFATE ION, Vascular endothelial growth factor receptor 2, methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylate 著者 Hilberg, F, Roth, G.J, Krssak, M, Kautschitsch, S, Sommergruber, W, Tontsch-Grunt, U, Garin-Chesa, P, Bader, G, Zoephel, A, Quant, J, Heckel, A, Rettig, W.J. 登録日 2008-02-08 公開日 2008-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy. Cancer Res., 68, 2008
7JQ2	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI5 分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-L-valyl-3-cyclohexyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-alaninamide 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
2F16	Crystal structure of the yeast 20S proteasome in complex with bortezomib 分子名称: N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, Proteasome component C1, Proteasome component C11, ... 著者 Groll, M. 登録日 2005-11-14 公開日 2006-03-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of the Boronic Acid-Based Proteasome Inhibitor Bortezomib in Complex with the Yeast 20S Proteasome. Structure, 14, 2006
7JPY	Crystal structure of the SARS-CoV-2 main protease in its apo-form 分子名称: 3C-like proteinase 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
7JQ4	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI7 分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-threonyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
2L6S	Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide 分子名称: VIR-576 著者 Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Canales-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Standker, L, Kirchhoff, F, Schmidt, R.E. 登録日 2010-11-24 公開日 2011-01-19 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide. Sci Transl Med, 2, 2010
7JQ0	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI3 分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-L-valyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
2F9U	HCV NS3 protease domain with NS4a peptide and a ketoamide inhibitor with a P2 norborane 分子名称: 1,1-DIMETHYLETHYL [1-CYCLOHEXYL-2-[3-[[[1-[2-[[2-[[2-(DIMETHYLAMINO)-2-OXO-1-PHENYLETHYL]AMINO]-2-OXOETHYL]AMINO]-1,2-DIOXOETHYL]PENTYL]AMINO]CARBONYL]-2-AZABICYCLO[2.2.1]HEPTAN-2-YL]-2-OXOETHYL]CARBAMATE, NS3 protease/helicase', ZINC ION, ... 著者 Venkatraman, S, Njoroge, F.G, Wu, W, Girijavallabhan, V, Prongay, A.J, Butkiewicz, N, Pichardo, J. 登録日 2005-12-06 公開日 2006-06-06 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Novel Inhibitors of Hepatitis C NS3-NS4A Serine Protease Derived from 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid. Bioorg.Med.Chem.Lett., 16, 2006
1YV4	X-ray structure of M23L onconase at 100K 分子名称: P-30 protein, SULFATE ION 著者 Merlino, A, Mazzarella, L, Carannante, A, Di Fiore, A, Di Donato, A, Notomista, E, Sica, F. 登録日 2005-02-15 公開日 2005-03-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 The Importance of Dynamic Effects on the Enzyme Activity: X-RAY STRUCTURE AND MOLECULAR DYNAMICS OF ONCONASE MUTANTS J.Biol.Chem., 280, 2005
2Z7U	Crystal Structure of H2O2 treated Cu,Zn-SOD 分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION 著者 Ito, S, Ishii, T, Uchida, K. 登録日 2007-08-28 公開日 2008-09-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of H2O2-treated Cu,Zn-superoxide dismutase To be Published
1UUZ	IVY:A NEW FAMILY OF PROTEIN 分子名称: INHIBITOR OF VERTEBRATE LYSOZYME, LYSOZYME C 著者 Abergel, C, Lembo, F, Byrne, D, Maza, C, Claverie, J.M. 登録日 2004-01-12 公開日 2004-01-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and Evolution of the Ivy Protein Family, Unexpected Lysozyme Inhibitors in Gram-Negative Bacteria. Proc.Natl.Acad.Sci.USA, 104, 2007
2HW2	Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin 分子名称: GLYCINE, RIFAMPICIN, Rifampin ADP-ribosyl transferase 著者 Baysarowich, J, Wright, G.D, Junop, M. 登録日 2006-07-31 公開日 2007-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr. Proc.Natl.Acad.Sci.Usa, 105, 2008
2JWK	Solution Structure of the periplasmic domain of TolR from Haemophilus influenzae 分子名称: Protein tolR 著者 Parsons, L.M, Bax, A. 登録日 2007-10-15 公開日 2008-04-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The Periplasmic Domain of TolR from Haemophilus influenzae Forms a Dimer with a Large Hydrophobic Groove: NMR Solution Structure and Comparison to SAXS Data. Biochemistry, 47, 2008
1SHU	Crystal Structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor 分子名称: Anthrax toxin receptor 2, MAGNESIUM ION 著者 Lacy, D.B, Wigelsworth, D.J, Scobie, H.M, Young, J.A.T, Collier, R.J. 登録日 2004-02-26 公開日 2004-04-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor Proc.Natl.Acad.Sci.USA, 101, 2004
1SA4	human protein farnesyltransferase complexed with FPP and R115777 分子名称: 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, FARNESYL DIPHOSPHATE, Protein farnesyltransferase beta subunit, ... 著者 Reid, T.S, Beese, L.S. 登録日 2004-02-06 公開日 2004-06-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity. Biochemistry, 43, 2004
2JWL	Solution Structure of periplasmic domain of TolR from H. influenzae with SAXS data 分子名称: Protein tolR 著者 Parsons, L.M, Bax, A, Grishaev, A. 登録日 2007-10-15 公開日 2008-04-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The Periplasmic Domain of TolR from Haemophilus influenzae Forms a Dimer with a Large Hydrophobic Groove: NMR Solution Structure and Comparison to SAXS Data. Biochemistry, 47, 2008

<123124125126127128129130131132133134135136137138>