PDB: 22592 件ウェブページステータス検索Chemie searchBIRD

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4EWL	Crystal Structure of MshB with glycerol and Acetate bound in the active site 分子名称: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ... 著者 Broadley, S.G, Sewell, B.T, Weber, B.W, Marakalala, M.J, Steenkamp, D.J. 登録日 2012-04-27 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A new crystal form of MshB from Mycobacterium tuberculosis with glycerol and acetate in the active site suggests the catalytic mechanism. Acta Crystallogr.,Sect.D, 68, 2012
4ISB	Crystal Structure of Apo Mtb FadD10 分子名称: Long chain fatty acid CoA ligase FadD10, SULFATE ION 著者 Liu, Z, Wang, F, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2013-01-16 公開日 2013-05-08 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of Mycobacterium tuberculosis FadD10 protein reveal a new type of adenylate-forming enzyme. J.Biol.Chem., 288, 2013
2WTL	Crystal structure of BfrA from M. tuberculosis 分子名称: BACTERIOFERRITIN, FE (III) ION, UNKNOWN ATOM OR ION, ... 著者 Gupta, V, Gupta, R.K, Khare, G, Salunke, D.M, Tyagi, A.K. 登録日 2009-09-17 公開日 2009-12-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Crystal Structure of Bfra from Mycobacterium Tuberculosis:Incorporation of Selenomethionine Results in Cleavage and Demetallation of Haem Plos One, 4, 2009
2E02	Crystal structure of H369L mutant of yeast bleomycin hydrolase 分子名称: Cysteine proteinase 1 著者 O'Farrell, P.A, Joshua-Tor, L. 登録日 2006-10-01 公開日 2007-08-14 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure Biochem.J., 401, 2007
2E03	Crystal structure of NQ67E mutant of yeast bleomycin hydrolase 分子名称: Cysteine proteinase 1 著者 O'Farrell, P.A, Joshua-Tor, L. 登録日 2006-10-01 公開日 2007-08-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure Biochem.J., 401, 2007
4LVQ	Crystal structure of the M. tuberculosis phosphate binding protein PstS3 分子名称: PHOSPHATE ION, Phosphate-binding protein PstS 3 著者 Ferraris, D.M, Rizzi, M. 登録日 2013-07-26 公開日 2014-03-26 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the Mycobacterium tuberculosis phosphate binding protein PstS3. Proteins, 82, 2014
2DZZ	Crystal structure of N392V mutant of yeast bleomycin hydrolase 分子名称: Cysteine proteinase 1 著者 O'Farrell, P.A, Joshua-Tor, L. 登録日 2006-09-30 公開日 2007-08-14 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure Biochem.J., 401, 2007
2DZY	Crystal structure of N392A mutant of yeast bleomycin hydrolase 分子名称: Cysteine proteinase 1 著者 O'Farrell, P.A, Joshua-Tor, L. 登録日 2006-09-30 公開日 2007-08-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure Biochem.J., 401, 2007
2E01	Crystal structure of H369A mutant of yeast bleomycin hydrolase 分子名称: Cysteine proteinase 1 著者 O'Farrell, P.A, Joshua-Tor, L. 登録日 2006-10-01 公開日 2007-08-14 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure Biochem.J., 401, 2007
3BAF	Crystal structure of shikimate kinase from Mycobacterium tuberculosis in complex with AMP-PNP 分子名称: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Shikimate kinase 著者 Faim, L.M, Dias, M.V.B, Vasconcelos, I.G, Basso, L.A, Santos, D.S, Azevedo, W.F, Ruggiero, N.J. 登録日 2007-11-07 公開日 2008-11-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure for shikimate kinase from Mycobacterium tuberculosis in complex with AMP-PNP To be Published
4IR7	Crystal Structure of Mtb FadD10 in Complex with Dodecanoyl-AMP 分子名称: 5'-O-[(S)-(dodecanoyloxy)(hydroxy)phosphoryl]adenosine, Long chain fatty acid CoA ligase FadD10, MAGNESIUM ION 著者 Liu, Z, Wang, F, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2013-01-14 公開日 2013-05-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of Mycobacterium tuberculosis FadD10 protein reveal a new type of adenylate-forming enzyme. J.Biol.Chem., 288, 2013
2WGY	Crystal structure of the G243A mutant of CYP130 from M. tuberculosis 分子名称: CYTOCHROME P450 130, ISOPROPYL ALCOHOL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Podust, L.M, Ouellet, H, von Kries, J.P, Ortiz de Montellano, P.R. 登録日 2009-04-28 公開日 2009-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines. J. Biol. Chem., 284, 2009
4BQP	Mtb InhA complex with Methyl-thiazole compound 7 分子名称: (1S)-1-(5-{[1-(2,6-DIFLUOROBENZYL)-1H-PYRAZOL-3-YL]AMINO}-1,3,4-THIADIAZOL-2-YL)-1-(4-METHYL-1,3-THIAZOL-2-YL)ETHANOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Read, J.A, Gingell, H, Madhavapeddi, P, Shirude, P.S. 登録日 2013-05-31 公開日 2013-12-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Methyl-Thiazoles: A Novel Mode of Inhibition with the Potential to Develop Novel Inhibitors Targeting Inha in Mycobacterium Tuberculosis. J.Med.Chem., 56, 2013
4A6A	A115V variant of dCTP deaminase-dUTPase from Mycobacterium tuberculosis in complex with dTTP 分子名称: DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE 著者 Lovgreen, M.N, Ucar, E, Willemoes, M, Harris, P. 登録日 2011-11-01 公開日 2012-10-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Dttp Inhibition of the Bifunctional Dctp Deaminase- Dutpase from Mycobacterium Tuberculosis is Ph Dependent: Kinetic Analyses and Crystal Structure of A115V Variant To be Published
3S1T	Structure of the regulatory domain of aspartokinase (Rv3709c; AK-beta) in complex with threonine from Mycobacterium tuberculosis 分子名称: Aspartokinase, SULFATE ION, THREONINE 著者 Schuldt, L, Mueller-Dieckmann, J, Weiss, M.S. 登録日 2011-05-16 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 High-resolution X-ray structure of the regulatory domain of the mycobacterial aspartokinase in complex with threonine To be Published
2ZI8	Crystal structure of the HsaC extradiol dioxygenase from M. tuberculosis in complex with 3,4-dihydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione (DHSA) 分子名称: 3,4-dihydroxy-9,10-secoandrosta-1(10),2,4-triene-9,17-dione, FE (II) ION, PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC 著者 D'Angelo, I, Yam, K.C, Eltis, L.D, Strynadka, N. 登録日 2008-02-13 公開日 2009-02-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis. Plos Pathog., 5, 2009
4G3P	Crystal structure of GlmU from Mycobacterium tuberculosis Snapshot 3 分子名称: Bifunctional protein GlmU, COBALT (II) ION, MAGNESIUM ION, ... 著者 Jagtap, P.A, Verma, S.K, Prakash, B. 登録日 2012-07-15 公開日 2013-08-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Structural Snapshots of Glmu from Mycobacterium Tuberculosis To be Published
2MI6	Solution structure of the carboxy terminal domain of NusG from Mycobacterium tuberculosis 分子名称: Transcription termination/antitermination protein NusG 著者 Strauss, M, Schweimer, K, Roesch, P. 登録日 2013-12-09 公開日 2014-01-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of the carboxy terminal domain of NusG from mycobacterium tuberculosis To be Published
2YPP	3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules 分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 Blackmore, N.J, Reichau, S, Jiao, W, Hutton, R.D, Baker, E.N, Jameson, G.B, Parker, E.J. 登録日 2012-10-31 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis. J.Mol.Biol., 425, 2013
5OO9	Streptomyces PAC13 (Y55F) with uridine 分子名称: Putative cupin_2 domain-containing isomerase, URIDINE 著者 Chung, C, Michailidou, F. 登録日 2017-08-06 公開日 2017-08-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3'-Deoxy Nucleoside of Pacidamycins. Angew. Chem. Int. Ed. Engl., 56, 2017
4LV4	A noncompetitive inhibitor for M. tuberculosis's class IIa fructose 1,6-bisphosphate aldolase 分子名称: 8-hydroxyquinoline-2-carboxylic acid, ACETATE ION, Fructose-bisphosphate aldolase, ... 著者 Capodagli, G.C, Pegan, S.D. 登録日 2013-07-25 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 A Noncompetitive Inhibitor for Mycobacterium tuberculosis's Class IIa Fructose 1,6-Bisphosphate Aldolase. Biochemistry, 53, 2014
3RV8	Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Cyclopropyl R-Group 分子名称: 3-{[(E)-1-carboxy-2-cyclopropylethenyl]oxy}-2-hydroxybenzoic acid, 3-{[(Z)-1-carboxy-2-cyclopropylethenyl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI 著者 Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) 登録日 2011-05-06 公開日 2012-05-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis Biochemistry, 51, 2012
3RV7	Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Isopropyl R-Group 分子名称: 3-{[(1Z)-1-carboxy-3-methylbut-1-en-1-yl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI 著者 Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) 登録日 2011-05-06 公開日 2012-05-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis Biochemistry, 51, 2012
3RV6	Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Phenyl R-Group 分子名称: 3-{[(E)-1-carboxy-2-phenylethenyl]oxy}-2-hydroxybenzoic acid, 3-{[(Z)-1-carboxy-2-phenylethenyl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI, ... 著者 Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) 登録日 2011-05-06 公開日 2012-05-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis Biochemistry, 51, 2012
3AFF	Crystal structure of the HsaA monooxygenase from M. tuberculosis 分子名称: Hydroxylase, putative 著者 D'Angelo, I, Lin, L.Y, Dresen, C, Tocheva, E.I, Strynadka, N, Eltis, L.D. 登録日 2010-02-28 公開日 2010-05-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism J.Biol.Chem., 285, 2010

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