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7LYY
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Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0075164
分子名称: (1s,3R,5S,7s)-N-[(1r,4r)-4-aminocyclohexyl]-3,5-diphenyladamantane-1-carboxamide, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-03-08
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0075164
to be published
4V5W
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Grapevine Fanleaf virus
分子名称: COAT PROTEIN
著者Schellenberger, P, Demangeat, G, Ritzenthaler, C, Lorber, B, Sauter, C.
登録日2011-05-10
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Exploiting Protein Engineering and Crystal Polymorphism for Successful X-Ray Structure Determination
Cryst.Growth Des., 11, 2011
7LYD
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Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0075146
分子名称: (1R,3S,5S,7S)-N-[(1r,4R)-4-aminocyclohexyl]-3-[(methylsulfanyl)methyl]-5-phenyladamantane-1-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-03-06
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0075146
to be published
7M2D
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Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0074953
分子名称: (1R,3S,5R,7R)-N-[(1r,4R)-4-aminocyclohexyl]-3-(ethoxymethyl)-5-phenyladamantane-1-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, GP1, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-03-16
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0074953
to be published
6DNV
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Crystal Structure of Neisseria meningitidis DsbD n-terminal domain in the reduced form
分子名称: SULFATE ION, Thiol:disulfide interchange protein DsbD
著者Smith, R.P, Heras, B, Paxman, J.J.
登録日2018-06-08
公開日2018-09-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens.
J. Biol. Chem., 293, 2018
4V7R
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BU of 4v7r by Molmil
Yeast 80S ribosome.
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Ben-Shem, A, Jenner, L, Yusupova, G, Yusupov, M.
登録日2010-07-23
公開日2014-07-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal structure of the eukaryotic ribosome.
Science, 330, 2010
6DO4
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BU of 6do4 by Molmil
KLHDC2 ubiquitin ligase in complex with SelS C-end degron
分子名称: Kelch domain-containing protein 2, SELS C-END DEGRON
著者Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N.
登録日2018-06-08
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
2G72
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Structure of hPNMT with inhibitor 3-fluoromethyl-7-thiomorpholinosulfonamide-THIQ and AdoMet
分子名称: (3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE, Phenylethanolamine N-methyltransferase, S-ADENOSYLMETHIONINE
著者Tyndall, J.D.A, Gee, C.L, Martin, J.L.
登録日2006-02-27
公開日2007-02-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enzyme Adaptation to Inhibitor Binding: A Cryptic Binding Site in Phenylethanolamine N-Methyltransferase
J.Med.Chem., 50, 2007
4V59
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Crystal structure of fatty acid synthase complexed with nadp+ from thermomyces lanuginosus at 3.1 angstrom resolution.
分子名称: FATTY ACID SYNTHASE ALPHA SUBUNITS, FATTY ACID SYNTHASE BETA SUBUNITS, FLAVIN MONONUCLEOTIDE, ...
著者Jenni, S, Leibundgut, M, Boehringer, D, Frick, C, Mikolasek, B, Ban, N.
登録日2007-03-09
公開日2014-07-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling
Science, 316, 2007
6QFI
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BU of 6qfi by Molmil
Structure of human Mcl-1 in complex with BIM BH3 peptide
分子名称: Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION
著者Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E.
登録日2019-01-10
公開日2019-06-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
6DA7
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BU of 6da7 by Molmil
Crystal structure of the TtnD decarboxylase from the tautomycetin biosynthesis pathway of Streptomyces griseochromogenes with apo form at 1.83 A resolution (I222)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, SODIUM ION, ...
著者Han, L, Rudolf, J.D, Chang, C.-Y, Miller, M.D, Soman, J, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2018-05-01
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway.
ACS Chem. Biol., 13, 2018
2G5W
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BU of 2g5w by Molmil
X-ray crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 (AtOPR3) in complex with 8-iso prostaglandin A1 and its cofactor, flavin mononucleotide.
分子名称: (8S,12S)-15S-HYDROXY-9-OXOPROSTA-10Z,13E-DIEN-1-OIC ACID, 12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE
著者Han, B.W, Malone, T.E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Fox, B.G, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-02-23
公開日2006-04-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.576 Å)
主引用文献Crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 in complex with 8-iso prostaglandin A(1).
Proteins, 79, 2011
5VHY
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BU of 5vhy by Molmil
GluA2-2xGSG1L bound to ZK
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
著者Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
登録日2017-04-13
公開日2017-05-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
6DU0
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BU of 6du0 by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395L mutant
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, GLYCEROL, ...
著者Salay, L.E, Chazin, W.J.
登録日2018-06-18
公開日2018-12-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DCD
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BU of 6dcd by Molmil
Mycobacterium marinum cytochrome P450 CYP150A6 in the substrate-free form
分子名称: Cytochrome P450 150A6 Cyp150A6, PROTOPORPHYRIN IX CONTAINING FE
著者Child, S.A, Bruning, J.B, Bell, S.G.
登録日2018-05-05
公開日2019-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The characterisation of two members of the cytochrome P450 CYP150 family: CYP150A5 and CYP150A6 from Mycobacterium marinum.
Biochim Biophys Acta Gen Subj, 1863, 2019
4WCH
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BU of 4wch by Molmil
Structure of Isolated D Chain of Gigant Hemoglobin from Glossoscolex paulistus
分子名称: Isolated Chain D of Gigant Hemoglobin from Glossoscolex Paulistus, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE
著者Bachega, J.F.R, Maluf, F.V, Pereira, H.M, Brandao-Neto, J, Tabak, M, Garratt, R.C, Horjales, E.
登録日2014-09-04
公開日2015-06-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The structure of the giant haemoglobin from Glossoscolex paulistus.
Acta Crystallogr.,Sect.D, 71, 2015
6QH8
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BU of 6qh8 by Molmil
Structure of knotted YibK from P. aeruginosa
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, tRNA (cytidine(34)-2'-O)-methyltransferase
著者Mikula, K.M, Tascon, I, Iwai, H.
登録日2019-01-16
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Tying up the Loose Ends: A Mathematically Knotted Protein.
Front Chem, 9, 2021
4WE1
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BU of 4we1 by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-2-naphthonitrile (JLJ600)
分子名称: 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}naphthalene-2-carbonitrile, Gag-Pol polyprotein, MAGNESIUM ION, ...
著者Frey, K.M, Anderson, K.S.
登録日2014-09-09
公開日2014-12-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.491 Å)
主引用文献Picomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers.
Acs Med.Chem.Lett., 5, 2014
7LCU
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BU of 7lcu by Molmil
X-ray structure of Furin bound to BOS-318, a small molecule inhibitor
分子名称: (1-{[2-(3,5-dichlorophenyl)-6-{[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]oxy}pyridin-4-yl]methyl}piperidin-4-yl)acetic acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Campobasso, N, Reid, R.
登録日2021-01-11
公開日2022-01-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease.
Cell Chem Biol, 29, 2022
6DHT
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BU of 6dht by Molmil
Bacteroides ovatus GH9 Bacova_02649
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Koropatkin, N.M, Foley, M.H.
登録日2018-05-21
公開日2019-04-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献A Cell-Surface GH9 Endo-Glucanase Coordinates with Surface Glycan-Binding Proteins to Mediate Xyloglucan Uptake in the Gut Symbiont Bacteroides ovatus.
J. Mol. Biol., 431, 2019
7QXV
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BU of 7qxv by Molmil
Crystal Structure of Haem-Binding Protein HemS Mutant F104A F199A, from Yersinia enterocolitica
分子名称: DI(HYDROXYETHYL)ETHER, Hemin transport protein
著者Barker, P.D, Keith, A, Brear, P, Wales, D.
登録日2022-01-27
公開日2023-02-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Crystal Structure of Haem-Binding Protein HemS Mutant F104A F199A, from Yersinia enterocolitica
To Be Published
6DI8
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BU of 6di8 by Molmil
Crystal structure of bovine alpha-chymotrypsin in space group P65
分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ...
著者Marshall, A.C, Keiller, B.G, Bruning, J.B.
登録日2018-05-23
公開日2019-01-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.859 Å)
主引用文献Crystal Structure of Bovine Alpha-Chymotrypsin in Space Group P65
Crystals, 8, 2018
4V65
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Structure of the E. coli ribosome in the Pre-accommodation state
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Devkota, B, Caulfield, T.R, Tan, R.-Z, Harvey, S.C.
登録日2008-08-03
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献The Structure of the E. coli Ribosome Before and After Accommodation: Implications for Proofreading
To be Published
6QFF
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Crystal Structure of Human Kallikrein 6 in complex with GSK144
分子名称: 4-[(5-phenyl-1~{H}-imidazol-2-yl)methylamino]-2-(pyridin-3-ylmethoxy)benzenecarboximidamide, GLYCEROL, Kallikrein-6
著者Thorpe, J.H.
登録日2019-01-10
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome.
Acta Crystallogr.,Sect.F, 75, 2019
4V6I
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Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ...
著者Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
登録日2010-10-12
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010

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