PDB: 185169 件ウェブページステータス検索Chemie searchBIRD

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1I8Z	CARBONIC ANHYDRASE II COMPLEXED WITH AL-6629 2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE, 2-(3-METHOXYPHENYL)-3-(4-MORPHOLINYL)-, 1,1-DIOXIDE 分子名称: 6-[N-(3-METHOXY-PHENYL)-3-(MORPHOLIN-4-YLMETHYL)-2H-THIENO[3,2-E]-1,2-THIAZINE-1,1,-DIOXIDE]-SULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... 著者 Kim, C.-Y, Chang, J.S, Liao, J, May, J.A, Christianson, D.W. 登録日 2001-03-16 公開日 2001-03-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IV. J.Med.Chem., 45, 2002
1I90	CARBONIC ANHYDRASE II COMPLEXED WITH AL-8520 2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE, 4-AMINO-3,4-DIHYDRO-2-(3-METHOXYPROPYL)-, 1,1-DIOXIDE, (R) 分子名称: 4-AMINO-6-[N-(3-METHOXYLPROPYL)-2H-THIENO[3,2-E][1,2]THIAZINE 1,1-DIOXIDE]-SULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... 著者 Kim, C.-Y, Chang, J.S, Liao, J, May, J.A, Christianson, D.W. 登録日 2001-03-16 公開日 2001-03-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IV. J.Med.Chem., 45, 2002
3JXW	Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors 分子名称: 8-[(E)-2-cyclopropylethenyl]-2-[(dimethylamino)methyl][1]benzothieno[3,2-d]pyrimidin-4(3H)-one, Proto-oncogene serine/threonine-protein kinase Pim-1 著者 Stoll, V.S. 登録日 2009-09-21 公開日 2009-11-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors TO BE PUBLISHED
6Q68	Crystal structure of bovine ACBD3 GOLD domain in complex with 3A protein of enterovirus-F2 (fusion protein) 分子名称: Acyl-CoA binding domain containing 3, Genome polyprotein, beta-D-glucopyranose 著者 Smola, M, Boura, E, Klima, M. 登録日 2018-12-10 公開日 2019-11-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.161 Å) 主引用文献 Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses. Arch. Virol., 165, 2020
1PPM	CRYSTALLOGRAPHIC ANALYSIS OF TRANSITION-STATE MIMICS BOUND TO PENICILLOPEPSIN: PHOSPHORUS-CONTAINING PEPTIDE ANALOGUES 分子名称: N-[(benzyloxy)carbonyl]-L-alanyl-N-{(1S)-1-[(R)-[(1R)-1-benzyl-2-methoxy-2-oxoethoxy](hydroxy)phosphoryl]-3-methylbutyl }-L-alaninamide, PENICILLOPEPSIN, SULFATE ION, ... 著者 Fraser, M.E, James, M.N.G. 登録日 1992-06-01 公開日 1993-10-31 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues. Biochemistry, 31, 1992
3HYF	Crystal structure of HIV-1 RNase H p15 with engineered E. coli loop and active site inhibitor 分子名称: 2-(3,4-dichlorobenzyl)-5,6-dihydroxypyrimidine-4-carboxylic acid, ACETATE ION, GLYCEROL, ... 著者 Lansdon, E.B, Kirschberg, T.A. 登録日 2009-06-22 公開日 2009-10-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information. J.Med.Chem., 52, 2009
1Q0A	Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator (space group C222) 分子名称: SULFATE ION, ZINC ION, Zn(II)-responsive regulator of zntA 著者 Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. 登録日 2003-07-15 公開日 2003-09-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR Science, 301, 2003
4JS4	Crystal structure of E. coli Exonuclease I in complex with a dA16 oligonucleotide 分子名称: Exodeoxyribonuclease I, SULFATE ION, dT16 oligonucleotide 著者 Bell, C.E. 登録日 2013-03-22 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structures of Escherichia coli exonuclease I in complex with single-stranded DNA provide insights into the mechanism of processive digestion. Nucleic Acids Res., 41, 2013
3FUA	L-FUCULOSE-1-PHOSPHATE ALDOLASE CRYSTAL FORM K 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, L-FUCULOSE-1-PHOSPHATE ALDOLASE, ... 著者 Dreyer, M.K, Schulz, G.E. 登録日 1996-02-14 公開日 1996-10-14 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Catalytic mechanism of the metal-dependent fuculose aldolase from Escherichia coli as derived from the structure. J.Mol.Biol., 259, 1996
1MHH	Structure of P. magnus protein L mutant bound to a mouse Fab 分子名称: 1,2-ETHANEDIOL, Fab, heavy chain, ... 著者 Graille, M, Stura, E.A. 登録日 2002-08-20 公開日 2003-01-14 最終更新日 2018-01-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Evidence for plasticity and structural mimicry at the immunoglobulin light chain-protein L interface J.Biol.Chem., 277, 2002
7BOG	Bacterial 30S ribosomal subunit assembly complex state E (body domain) 分子名称: 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... 著者 Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. 登録日 2021-01-25 公開日 2021-07-07 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.75 Å) 主引用文献 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
1L6Y	Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4-Oxosebacic Acid 分子名称: 4-OXODECANEDIOIC ACID, GLYCEROL, MAGNESIUM ION, ... 著者 Jaffe, E.K, Kervinen, J, Martins, J, Stauffer, F, Neier, R, Wlodawer, A, Zdanov, A. 登録日 2002-03-14 公開日 2002-04-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid J.Biol.Chem., 277, 2002
3I05	Tryptophanyl-tRNA synthetase from Trypanosoma brucei 分子名称: Tryptophanyl-tRNA synthetase 著者 Arakaki, T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) 登録日 2009-06-24 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase. Mol.Biochem.Parasitol., 177, 2011
2BPM	STRUCTURE OF CDK2-CYCLIN A WITH PHA-630529 分子名称: (2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ... 著者 Cameron, A, Fogliatto, G, Pevarello, P, Brasca, M.G, Orsini, P, Traquandi, G, Longo, A, Nesi, M, Orzi, F, Piutti, C, Sansonna, P, Varasi, M, Vulpetti, A, Roletto, F, Alzani, R, Ciomei, M, Albanese, C, Pastori, W, Marsiglio, A, Pesenti, E, Fiorentini, F, Bischoff, J.R, Mercurio, C. 登録日 2005-04-21 公開日 2005-12-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 3-Aminopyrazole Inhibitors of Cdk2-Cyclin a as Antitumor Agents. 2. Lead Optimization J.Med.Chem., 48, 2005
1Q3C	Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The E2A mutant at 2.3 resolution. 分子名称: Endonuclease VIII, GLYCEROL, MAGNESIUM ION, ... 著者 Golan, G, Zharkov, D.O, Feinberg, H, Fernandes, A.S, Zaika, E.I, Kycia, J.H, Grollman, A.P, Shoham, G. 登録日 2003-07-29 公開日 2004-08-03 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility. Nucleic Acids Res., 33, 2005
2Y2Y	Oxidised form of E. coli CsgC 分子名称: ACETATE ION, CURLI PRODUCTION PROTEIN CSGC 著者 Taylor, J.D, Salgado, P.S, Constable, S.C, Cota, E, Mathews, S.J. 登録日 2010-12-16 公開日 2011-09-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Atomic Resolution Insights Into Curli Fiber Biogenesis. Structure, 19, 2011
2QST	Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA) 分子名称: Carcinoembryonic antigen-related cell adhesion molecule 5 著者 Le Trong, I, Korotkova, N, Moseley, S.L, Stenkamp, R.E. 登録日 2007-07-31 公開日 2008-01-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation. Mol.Microbiol., 67, 2008
6MRW	14-meric ClyA pore complex 分子名称: Hemolysin E, chromosomal 著者 Peng, W, de Souza Santos, M, Li, Y, Tomchick, D.R, Orth, K. 登録日 2018-10-15 公開日 2019-05-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers. Plos One, 14, 2019
1HGT	STRUCTURE OF THE HIRUGEN AND HIRULOG 1 COMPLEXES OF ALPHA-THROMBIN 分子名称: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUGEN 著者 Tulinsky, A, Skrzypczak-Jankun, E. 登録日 1991-06-03 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the hirugen and hirulog 1 complexes of alpha-thrombin. J.Mol.Biol., 221, 1991
7WTL	Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Dis-D 分子名称: 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... 著者 Cheng, J, La Venuta, G, Lau, B, Berninghausen, O, Beckmann, R, Hurt, E. 登録日 2022-02-05 公開日 2022-10-19 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation. Nucleic Acids Res., 50, 2022
7MCH	Crystal structure of a single-chain E/F type bilin lyase-isomerase MpeQ in space group C2221 分子名称: bilin lyase-isomerase 著者 Yang, X, Kumarapperuma, I. 登録日 2021-04-02 公開日 2022-08-24 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal structure and molecular mechanism of an E/F type bilin lyase-isomerase. Structure, 30, 2022
3K7D	C-terminal (adenylylation) domain of E.coli Glutamine Synthetase Adenylyltransferase 分子名称: Glutamate-ammonia-ligase adenylyltransferase, SULFATE ION 著者 Xu, Y, Carr, P.D, Vasudevan, S.G, Ollis, D.L. 登録日 2009-10-12 公開日 2009-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the Adenylylation Domain of E. coli Glutamine Synthetase Adenylyl Transferase: Evidence for Gene Duplication and Evolution of a New Active Site. J.Mol.Biol., 396, 2010
6MRT	12-meric ClyA pore complex 分子名称: Hemolysin E, chromosomal 著者 Peng, W, de Souza Santos, M, Li, Y, Tomchick, D.R, Orth, K. 登録日 2018-10-15 公開日 2019-05-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers. Plos One, 14, 2019
1NZP	Solution Structure of the Lyase Domain of Human DNA Polymerase Lambda 分子名称: DNA polymerase lambda 著者 DeRose, E.F, Kirby, T.W, Mueller, G.A, Bebenek, K, Garcia-Diaz, M, Blanco, L, Kunkel, T.A, London, R.E. 登録日 2003-02-19 公開日 2003-08-05 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the Lyase Domain of Human DNA Polymerase Lambda Biochemistry, 42, 2003
1AAW	THE STRUCTURAL BASIS FOR THE ALTERED SUBSTRATE SPECIFICITY OF THE R292D ACTIVE SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM E. COLI 分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Almo, S.C, Smith, D.L, Danishefsky, A.T, Ringe, D. 登録日 1993-07-13 公開日 1993-10-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli. Protein Eng., 7, 1994

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