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7EPF
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Crystal structure of mGlu2 bound to NAM597
分子名称: (8~{R})-4-[2,4-bis(fluoranyl)phenyl]-8-methyl-7-[(2-methylpyrazol-3-yl)methyl]-6,8-dihydro-5~{H}-1,7-naphthyridine-2-carboxamide, FLAVIN MONONUCLEOTIDE, Metabotropic glutamate receptor 2
著者Du, J, Wang, D, Lin, S, Han, S, Wu, B, Zhao, Q.
登録日2021-04-26
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of human mGlu2 and mGlu7 homo- and heterodimers.
Nature, 594, 2021
8HRX
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Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex
分子名称: Fab heavy chain from antibody IgG clone number YN9048, Fab light chain from antibody IgG clone number YN9048, PreS1 protein (Fragment), ...
著者Asami, J, Shimizu, T, Ohto, U.
登録日2022-12-16
公開日2024-01-17
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structural basis of hepatitis B virus receptor binding.
Nat.Struct.Mol.Biol., 31, 2024
8HRY
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Cryo-EM structure of human NTCP-myr-preS1-YN9016Fab complex
分子名称: Fab heavy chain from antibody IgG clone number YN9016, Fab light chain from antibody IgG clone number YN9016, Large S protein (Fragment), ...
著者Asami, J, Shimizu, T, Ohto, U.
登録日2022-12-16
公開日2024-01-17
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural basis of hepatitis B virus receptor binding.
Nat.Struct.Mol.Biol., 31, 2024
6YHH
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X-ray Structure of Flavobacterium johnsoniae chitobiase (FjGH20)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-N-acetylglucosaminidase-like protein Glycoside hydrolase family 20, GLYCEROL
著者Mazurkewich, S, Helland, R, MacKenzie, A, Eijsink, V.G.H, Pope, P.B, Branden, G, Larsbrink, J.
登録日2020-03-30
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae.
Sci Rep, 10, 2020
8HFI
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Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant desipramine in an inward-open state at resolution of 2.5 angstrom.
分子名称: 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, CHLORIDE ION, Sodium-dependent noradrenaline transporter
著者Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C.
登録日2022-11-10
公開日2024-05-15
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Molecular basis of human noradrenaline transporter reuptake and inhibition.
Nature, 632, 2024
7KYW
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BU of 7kyw by Molmil
Crystal structure of timothy grass allergen Phl p 12.0101 reveals an unusual profilin dimer
分子名称: CITRIC ACID, Profilin-1
著者O'Malley, A, Kapingidza, A.B, Hyduke, N, Dolamore, C, Chruszcz, M.
登録日2020-12-09
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of timothy grass allergen Phl p 12.0101 reveals an unusual profilin dimer.
Acta Biochim.Pol., 68, 2021
6AT6
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BU of 6at6 by Molmil
Crystal structure of the KFJ5 TCR
分子名称: T-cell receptor alpha variable 4, T-cell receptor, sp3.4 alpha chain chimera, ...
著者Gully, B.S, Rossjohn, J.
登録日2017-08-28
公開日2018-02-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.417 Å)
主引用文献Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
Nat Commun, 9, 2018
1D2P
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CRYSTAL STRUCTURE OF TWO B REPEAT UNITS (B1B2) OF THE COLLAGEN BINDING PROTEIN (CNA) OF STAPHYLOCOCCUS AUREUS
分子名称: COLLAGEN ADHESIN
著者Deivanayagam, C.C.S, Rich, R.L, Hook, M, Narayana, S.V.L.
登録日1999-09-25
公開日2000-09-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface protein.
Structure Fold.Des., 8, 2000
1CNE
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BU of 1cne by Molmil
STRUCTURAL STUDIES ON CORN NITRATE REDUCTASE: REFINED STRUCTURE OF THE CYTOCHROME B REDUCTASE FRAGMENT AT 2.5 ANGSTROMS, ITS ADP COMPLEX AND AN ACTIVE SITE MUTANT AND MODELING OF THE CYTOCHROME B DOMAIN
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NITRATE REDUCTASE
著者Lu, G, Lindqvist, Y, Schneider, G.
登録日1995-02-01
公開日1995-04-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural studies on corn nitrate reductase: refined structure of the cytochrome b reductase fragment at 2.5 A, its ADP complex and an active-site mutant and modeling of the cytochrome b domain.
J.Mol.Biol., 248, 1995
1D90
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BU of 1d90 by Molmil
REFINED CRYSTAL STRUCTURE OF AN OCTANUCLEOTIDE DUPLEX WITH I.T MISMATCHED BASE PAIRS
分子名称: DNA (5'-D(*GP*GP*IP*GP*CP*TP*CP*C)-3')
著者Cruse, W.B.T, Aymani, J, Kennard, O, Brown, T, Jack, A.G.C, Leonard, G.A.
登録日1992-10-17
公開日1993-07-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Refined crystal structure of an octanucleotide duplex with I.T. mismatched base pairs.
Nucleic Acids Res., 17, 1989
8POO
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BU of 8poo by Molmil
Low resolution structure of inactive conformation of the Ktr cation channel in presence of ATP and c-di-AMP
分子名称: Ktr system potassium uptake protein A, Ktr system potassium uptake protein B
著者Cereija, T.B, Teixeira-Duarte, C.M, Morais-Cabral, J.H.
登録日2023-07-05
公開日2024-05-15
実験手法X-RAY DIFFRACTION (5.77 Å)
主引用文献c-di-AMP determines the hierarchical organization of bacterial RCK proteins.
Proc.Natl.Acad.Sci.USA, 121, 2024
6YSL
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BU of 6ysl by Molmil
Structure of the flagellar MotAB stator complex from Bacillus subtilis
分子名称: Motility protein A, Motility protein B
著者Lea, S.M, Deme, J.C, Johnson, S.J.
登録日2020-04-22
公開日2020-08-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures of the stator complex that drives rotation of the bacterial flagellum.
Nat Microbiol, 5, 2020
1D1I
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MUTATED SHIGA-LIKE TOXIN B SUBUNIT (W34A) COMPLEXED WITH RECEPTOR GB3 ANALOGUE
分子名称: SHIGA TOXIN B-CHAIN, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Ling, H, Boodhoo, A, Brunton, J.L, Read, R.J.
登録日1999-09-17
公開日2000-09-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mutated Shiga-like Toxin B Subunit (W34A) Complexed with Receptor Gb3 Analogue
To be Published
7OR4
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BU of 7or4 by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B142
分子名称: Dipeptidyl peptidase 8, methyl 3-[4-[(4-bromophenyl)methyl]piperazin-1-yl]carbonyl-5-[(2-ethyl-2-methanoyl-butanoyl)amino]benzoate, trimethylamine oxide
著者Ross, B, Huber, R.
登録日2021-06-04
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 61, 2022
7OZ7
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BU of 7oz7 by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, L84
分子名称: Dipeptidyl peptidase 8, trimethylamine oxide, ~{N}-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]-2-ethyl-2-methanoyl-butanamide
著者Ross, B, Huber, R.
登録日2021-06-26
公開日2021-07-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 61, 2022
8IT0
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BU of 8it0 by Molmil
Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-2)
分子名称: DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ...
著者Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S.
登録日2023-03-21
公開日2023-10-18
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute.
Nature, 625, 2024
6B2P
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Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis
分子名称: 5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknB
著者Zuccola, H.J.
登録日2017-09-20
公開日2018-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.
ACS Med Chem Lett, 8, 2017
8IT1
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BU of 8it1 by Molmil
Cryo-EM structure of Crt-SPARTA-gRNA-tDNA tetramer (NADase active form)
分子名称: DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ...
著者Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S.
登録日2023-03-21
公開日2023-11-08
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute.
Nature, 625, 2024
1CQF
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BU of 1cqf by Molmil
THE COMPLEX OF THE MUTATED SHIGA TOXIN B SUBUNIT AND GB3 TRISACCHARIDE
分子名称: SHIGA TOXIN B-CHAIN, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Ling, H, Bast, D, Brunton, J.L, Read, R.J.
登録日1999-08-06
公開日2000-08-07
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Complex of the Mutated Shiga Toxin B Subunit and Gb3 Trisaccharide
To be Published
6ZHJ
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BU of 6zhj by Molmil
3D electron diffraction structure of thermolysin from Bacillus thermoproteolyticus
分子名称: CALCIUM ION, Thermolysin, ZINC ION
著者Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Schoehn, G, Ling, W.L, Abrahams, J.P.
登録日2020-06-23
公開日2021-01-27
最終更新日2024-01-24
実験手法ELECTRON CRYSTALLOGRAPHY (3.26 Å)
主引用文献Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
6ZHN
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3D electron diffraction structure of thaumatin from Thaumatococcus daniellii
分子名称: CHLORIDE ION, Thaumatin-1
著者Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Schoehn, G, Ling, W.L, Abrahams, J.P.
登録日2020-06-23
公開日2021-01-27
最終更新日2024-10-16
実験手法ELECTRON CRYSTALLOGRAPHY (2.76 Å)
主引用文献Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
1D40
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BASE SPECIFIC BINDING OF COPPER(II) TO Z-DNA: THE 1.3-ANGSTROMS SINGLE CRYSTAL STRUCTURE OF D(M5CGUAM5CG) IN THE PRESENCE OF CUCL2
分子名称: COPPER (II) CHLORIDE, COPPER (II) ION, DNA (5'-D(*(5CM)P*(CU)GP*UP*AP*(5CM)P*(CU)G)-3')
著者Geierstanger, B.H, Kagawa, T.F, Chen, S.-L, Quigley, G.J, Ho, P.S.
登録日1991-05-07
公開日1992-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Base-specific binding of copper(II) to Z-DNA. The 1.3-A single crystal structure of d(m5CGUAm5CG) in the presence of CuCl2.
J.Biol.Chem., 266, 1991
7P3W
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F1Fo-ATP synthase from Acinetobacter baumannii (state 3)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Demmer, J.K, Phillips, B.P, Uhrig, O.L, Filloux, A, Allsopp, L.P, Bublitz, M, Meier, T.
登録日2021-07-08
公開日2022-02-02
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure of ATP synthase from ESKAPE pathogen Acinetobacter baumannii.
Sci Adv, 8, 2022
7P3N
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F1Fo-ATP synthase from Acinetobacter baumannii (state 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Demmer, J.K, Phillips, B.P, Uhrig, O.L, Filloux, A, Allsopp, L.P, Bublitz, M, Meier, T.
登録日2021-07-08
公開日2022-02-02
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structure of ATP synthase from ESKAPE pathogen Acinetobacter baumannii.
Sci Adv, 8, 2022
7P2Y
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F1Fo-ATP synthase from Acinetobacter baumannii (state 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Demmer, J.K, Phillips, B.P, Uhrig, O.L, Filloux, A, Allsopp, L.P, Bublitz, M, Meier, T.
登録日2021-07-06
公開日2022-02-02
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of ATP synthase from ESKAPE pathogen Acinetobacter baumannii.
Sci Adv, 8, 2022

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