PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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4IMG	Crystal Structure of Pasteurella multocida N-Acetyl-D-Neuraminic acid lyase K164 mutant complexed with N-Glycolylneuraminic acid 分子名称: 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, 3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-D-galacto-non-2-ulosonic acid, N-acetylneuraminate lyase 著者 Fisher, A.J, Huynh, N. 登録日 2013-01-02 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural Basis for Substrate Specificity and Mechanism of N-Acetyl-d-neuraminic Acid Lyase from Pasteurella multocida. Biochemistry, 52, 2013
2JO0	The solution structure of the monomeric species of the C terminal domain of the CA protein of HIV-1 分子名称: Gag-Pol polyprotein 著者 Alcaraz, L.A, del Alamo, M, Barrera, F.N, Mateu, M.G, Neira, J.L. 登録日 2007-02-17 公開日 2007-07-31 最終更新日 2023-12-20 実験手法 SOLUTION NMR 主引用文献 Flexibility in HIV-1 Assembly Subunits: Solution Structure of the Monomeric C-Terminal Domain of the Capsid Protein Biophys.J., 93, 2007
4INI	Human Histidine Triad Nucleotide Binding Protein 2 with Bound AMP 分子名称: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Maize, K.M, Wagner, C.R, Finzel, B.C. 登録日 2013-01-04 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily. Febs J., 280, 2013
1RHH	Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution 分子名称: Fab X5, heavy chain, light chain 著者 Darbha, R, Phogat, S, Labrijn, A.F, Shu, Y, Gu, Y, Andrykovitch, M, Zhang, M.Y, Pantophlet, R, Martin, L, Vita, C, Burton, D.R, Dimitrov, D.S, Ji, X. 登録日 2003-11-14 公開日 2004-02-24 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of the Broadly Cross-Reactive HIV-1-Neutralizing Fab X5 and Fine Mapping of Its Epitope Biochemistry, 43, 2004
2E5P	Solution structure of the TUDOR domain of PHD finger protein 1 (PHF1 protein) 分子名称: PHD finger protein 1 著者 Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-12-22 公開日 2007-06-26 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the TUDOR domain of PHD finger protein 1 (PHF1 protein) To be Published
260L	AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME 分子名称: CHLORIDE ION, NICKEL (II) ION, PROTEIN (LYSOZYME) 著者 Wray, J.W, Baase, W.A, Ostheimer, G.J, Matthews, B.W. 登録日 1999-03-01 公開日 2000-09-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site. Protein Eng., 13, 2000
1TAD	GTPASE MECHANISM OF GPROTEINS FROM THE 1.7-ANGSTROM CRYSTAL STRUCTURE OF TRANSDUCIN ALPHA-GDP-ALF4- 分子名称: CACODYLATE ION, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Sondek, J, Lambright, D.G, Noel, J.P, Hamm, H.E, Sigler, P.B. 登録日 1995-01-05 公開日 1995-05-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4. Nature, 372, 1994
1E7Q	GDP 4-keto-6-deoxy-D-mannose epimerase reductase S107A 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... 著者 Rosano, C, Izzo, G, Bolognesi, M. 登録日 2000-09-07 公開日 2000-10-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
4K1R	Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain and Ubiquitin 分子名称: 1,2-ETHANEDIOL, AMSH-like protease sst2, CHLORIDE ION, ... 著者 Shrestha, R.K, Das, C. 登録日 2013-04-05 公開日 2014-04-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.632 Å) 主引用文献 Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53, 2014
2EQU	Solution structure of the tudor domain of PHD finger protein 20-like 1 分子名称: PHD finger protein 20-like 1 著者 Futami, K, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-30 公開日 2007-10-02 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the tudor domain of PHD finger protein 20-like 1 To be Published
3V8H	Crystal structure of Thymidylate Synthase from Burkholderia thailandensis 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Thymidylate synthase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-12-22 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
3VAL	Structure of U2AF65 variant with BrU5C1 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*C*UP*UP*UP*(BRU)P*UP*U)-3'), SULFATE ION, ... 著者 Jenkins, J.L, Frato, K.H, Kielkopf, C.L. 登録日 2011-12-29 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
5SHL	CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c1(cc(nn2c1nc(c2C)C)Cl)N3CCCC3, micromolar IC50=1.188091 分子名称: (4R)-6-chloro-2,3-dimethyl-8-(pyrrolidin-1-yl)imidazo[1,2-b]pyridazine, MAGNESIUM ION, ZINC ION, ... 著者 Joseph, C, Benz, J, Flohr, A, Groebke-Zbinden, K, Rudolph, M.G. 登録日 2022-02-01 公開日 2022-10-12 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structure of a human phosphodiesterase 10 complex To be published
1EKK	CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN THE R3 FORM WITH HYDROXYETHYLTHIAZOLE 分子名称: 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, HYDROXYETHYLTHIAZOLE KINASE, SULFUR DIOXIDE 著者 Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E. 登録日 2000-03-09 公開日 2000-08-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution. Biochemistry, 39, 2000
1E6U	GDP 4-keto-6-deoxy-D-mannose epimerase reductase 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... 著者 Rosano, C, Izzo, G, Bolognesi, M. 登録日 2000-08-23 公開日 2000-10-22 最終更新日 2025-10-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
1ZYX	Crystal structure of the complex of a group IIA phospholipase A2 with a synthetic anti-inflammatory agent licofelone at 1.9A resolution 分子名称: Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, [6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZIN-5-YL]ACETIC ACID 著者 Singh, N, Jabeen, T, Sharma, S, Bhushan, A, Singh, T.P. 登録日 2005-06-13 公開日 2005-06-28 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of the complex of a group IIA phospholipase A2 with a synthetic anti-inflammatory agent licofelone at 1.9A resolution To be Published
4KIW	Design and structural analysis of aromatic inhibitors of type II dehydroquinate dehydratase from Mycobacterium tuberculosis - compound 49e [5-[(3-nitrobenzyl)amino]benzene-1,3-dicarboxylic acid] 分子名称: 3-dehydroquinate dehydratase, 5-[(3-nitrobenzyl)amino]benzene-1,3-dicarboxylic acid 著者 Dias, M.V.B, Howard, N.G, Blundell, T.L, Abell, C. 登録日 2013-05-02 公開日 2014-05-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Design and Structural Analysis of Aromatic Inhibitors of Type II Dehydroquinase from Mycobacterium tuberculosis. Chemmedchem, 10, 2015
3VEO	Crystal structure of the O-carbamoyltransferase TobZ in complex with carbamoyl phosphate 分子名称: 1,2-ETHANEDIOL, FE (II) ION, O-carbamoyltransferase TobZ, ... 著者 Parthier, C, Stubbs, M.T, Goerlich, S, Jaenecke, F. 登録日 2012-01-09 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.187 Å) 主引用文献 The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction. Angew.Chem.Int.Ed.Engl., 51, 2012
4KPD	Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate 分子名称: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... 著者 Barnett, B.L, Tsoumpra, M.K, Muniz, J.R.C, Walter, R.L. 登録日 2013-05-13 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate To be Published
2JFM	CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE (UNLIGANDED FORM) 分子名称: 1,2-ETHANEDIOL, STE20-LIKE SERINE-THREONINE KINASE 著者 Pike, A.C.W, Rellos, P, Fedorov, O, Keates, T, Salah, E, Savitsky, P, Papagrigoriou, E, Bunkoczi, G, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S. 登録日 2007-02-02 公開日 2007-02-27 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites. Embo J., 27, 2008
1VLZ	UNCOUPLED PHOSPHORYLATION AND ACTIVATION IN BACTERIAL CHEMOTAXIS: THE 2.1 ANGSTROM STRUCTURE OF A THREONINE TO ISOLEUCINE MUTANT AT POSITION 87 OF CHEY 分子名称: CHEY 著者 Ganguli, S, Wang, H, Matsumura, P, Volz, K. 登録日 1995-04-21 公開日 1995-07-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Uncoupled phosphorylation and activation in bacterial chemotaxis. The 2.1-A structure of a threonine to isoleucine mutant at position 87 of CheY. J.Biol.Chem., 270, 1995
3AQC	M. luteus B-P 26 heterodimeric hexaprenyl diphosphate synthase in complex with magnesium and FPP analogue 分子名称: (2E,6E)-7,11-dimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, CHLORIDE ION, Component A of hexaprenyl diphosphate synthase, ... 著者 Sasaki, D, Fujihashi, M, Okuyama, N, Kobayashi, Y, Noike, M, Koyama, T, Miki, K. 登録日 2010-10-28 公開日 2010-11-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Crystal structure of heterodimeric hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26 reveals that the small subunit is directly involved in the product chain length regulation. J.Biol.Chem., 286, 2011
3ASL	Structure of UHRF1 in complex with histone tail 分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ... 著者 Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M. 登録日 2010-12-16 公開日 2012-01-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1 Proc.Natl.Acad.Sci.USA, 109, 2012
2KB9	Human Jagged-1, exon 6 分子名称: Jagged-1 著者 Pintar, A, Guarnaccia, C, Pongor, S. 登録日 2008-11-24 公開日 2009-07-28 最終更新日 2024-11-20 実験手法 SOLUTION NMR 主引用文献 Exon 6 of human JAG1 encodes a conserved structural unit Bmc Struct.Biol., 9, 2009
1EDT	CRYSTAL STRUCTURE OF ENDO-BETA-N-ACETYLGLUCOSAMINIDASE H AT 1.9 ANGSTROMS RESOLUTION: ACTIVE SITE GEOMETRY AND SUBSTRATE RECOGNITION 分子名称: ENDO-BETA-N-ACETYLGLUCOSAMINIDASE H, ENDO H 著者 Van Roey, P, Rao, V. 登録日 1995-03-31 公開日 1995-08-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of endo-beta-N-acetylglucosaminidase H at 1.9 A resolution: active-site geometry and substrate recognition. Structure, 3, 1995

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