PDB: 22592 件ウェブページステータス検索Chemie searchBIRD

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8PXY	Crystal structure of the transpeptidase LdtMt2 C354S mutant from Mycobacterium tuberculosis in complex with natural substrate 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 de Munnik, M, Schofield, C.J. 登録日 2023-07-24 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of the transpeptidase LdtMt2 C354S mutant from Mycobacterium tuberculosis in complex with natural substrate To Be Published
3FNH	Crystal structure of InhA bound to triclosan derivative 分子名称: 2-(2,4-DICHLOROPHENOXY)-5-(2-PHENYLETHYL)PHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Wang, F. 登録日 2008-12-24 公開日 2009-01-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Chemmedchem, 4, 2009
5FMP	KstR, transcriptional repressor of cholesterol degradation in Mycobacterium tuberculosis, bound to the DNA operator 分子名称: 5'-D(*CP*TP*AP*GP*AP*AP*CP*GP*TP*GP*TP*TP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*AP*AP*CP*AP*CP*GP*TP*TP*CP*TP*AP*G)-3', HTH-TYPE TRANSCRIPTIONAL REPRESSOR KSTR 著者 Podust, L.M, Ouellet, H. 登録日 2015-11-07 公開日 2016-11-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Kstr, Transcriptional Repressor of Cholesterol Degradation in Mycobacterium Tuberculosis To be Published
7CL2	The crystal structure of KanJ 分子名称: GLYCEROL, Kanamycin B dioxygenase, NICKEL (II) ION, ... 著者 Kitayama, Y, Miyanaga, A, Kudo, F, Eguchi, T. 登録日 2020-07-20 公開日 2021-01-13 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Stepwise Post-glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis. Chembiochem, 22, 2021
3FNE	Crystal structure of InhA bound to triclosan derivative 17 分子名称: 2-(2,4-DICHLOROPHENOXY)-5-(PYRIDIN-2-YLMETHYL)PHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Wang, F. 登録日 2008-12-24 公開日 2009-01-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Chemmedchem, 4, 2009
6WYM	Transition metal inhibition and structural refinement of the M. tuberculosis esterase, Rv0045c 分子名称: CHLORIDE ION, Possible hydrolase 著者 Macbeth, M.R, Johnson, R.J, Hoops, G.C. 登録日 2020-05-13 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045C. Protein Sci., 30, 2021
6WYN	Transition metal inhibition and structural refinement of the M. tuberculosis esterase, Rv0045c 分子名称: CHLORIDE ION, Possible hydrolase 著者 Macbeth, M.R, Johnson, R.J, Hoops, G.C. 登録日 2020-05-13 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045C. Protein Sci., 30, 2021
8RP3	Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (H126A mutant) 分子名称: 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase 著者 Mojanaga, O.O, Acharya, K.R, Lloyd, M.D. 登録日 2024-01-12 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site. Biomolecules, 14, 2024
8RP5	Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (E241A mutant) 分子名称: 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase, TRIETHYLENE GLYCOL 著者 Mojanaga, O.O, Acharya, K.R, Lloyd, M.D. 登録日 2024-01-12 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site. Biomolecules, 14, 2024
8RP4	Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (D156A mutant) 分子名称: 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase, DI(HYDROXYETHYL)ETHER 著者 Mojanaga, O.O, Acharya, K.R, Lloyd, M.D. 登録日 2024-01-12 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site. Biomolecules, 14, 2024
3FNF	Crystal structure of InhA bound to triclosan derivative 分子名称: 5-benzyl-2-(2,4-dichlorophenoxy)phenol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Wang, F. 登録日 2008-12-24 公開日 2009-01-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Chemmedchem, 4, 2009
7CDW	Crystal Structure of Mycobacterium Tuberculosis Elongation Factor G1 分子名称: Elongation factor G, GUANOSINE-5'-DIPHOSPHATE 著者 Gao, X, Cui, S. 登録日 2020-06-20 公開日 2021-09-22 最終更新日 2022-02-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of Mycobacterium tuberculosis Elongation Factor G1. Front Mol Biosci, 8, 2021
6WGY	Crystal structure of a Putative citrate synthase 2 from Mycobacterium bovis in complex with citrate 分子名称: CITRIC ACID, IODIDE ION, Putative citrate synthase 2 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-04-06 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a Putative citrate synthase 2 from Mycobacterium bovis in complex with citrate to be published
2HFJ	Pikromycin thioesterase with covalent pentaketide affinity label 分子名称: DIMETHYL SULFOXIDE, MAGNESIUM ION, SULFATE ION, ... 著者 Akey, D.L, Kittendorf, J.D, Giraldes, J.W, Fecik, R.A, Sherman, D.H, Smith, J.L. 登録日 2006-06-24 公開日 2006-09-19 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Basis for Macrolactonization by the Pikromycin Thioesterase NAT.CHEM.BIOL., 2, 2006
7WNU	Mycobacterium tuberculosis Rnase J complex with 7nt RNA 分子名称: RNA (5'-R(P*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease J, ZINC ION 著者 Li, J, Hu, J, Bao, L, Zhan, B, Li, Z. 登録日 2022-01-19 公開日 2023-01-25 最終更新日 2024-09-04 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural insights into RNase J that plays an essential role in Mycobacterium tuberculosis RNA metabolism Nat Commun, 14, 2023
2O2H	Crystal structure of haloalkane dehalogenase Rv2579 from Mycobacterium tuberculosis complexed with 1,2-dichloroethane 分子名称: 1,2-DICHLOROETHANE, ACETATE ION, CHLORIDE ION, ... 著者 Mazumdar, P.A, Hulecki, J, Cherney, M.M, Garen, C.R, James, M.N.G, TB Structural Genomics Consortium (TBSGC) 登録日 2006-11-29 公開日 2007-11-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of haloalkane dehalogenase Rv2579 from Mycobacterium tuberculosis complexed with 1,2-dichloroethane TO BE PUBLISHED
7YZI	Structure of Mycobacterium tuberculosis adenylyl cyclase Rv1625c / Cya 分子名称: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, MANGANESE (II) ION, ... 著者 Mehta, V, Khanppnavar, B, Korkhov, V.M. 登録日 2022-02-20 公開日 2022-10-05 実験手法 ELECTRON MICROSCOPY (3.83 Å) 主引用文献 Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases. Elife, 11, 2022
3FNG	Crystal structure of InhA bound to triclosan derivative 分子名称: 5-(cyclohexylmethyl)-2-(2,4-dichlorophenoxy)phenol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Wang, F. 登録日 2008-12-24 公開日 2009-01-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Chemmedchem, 4, 2009
2O2I	Crystal structure of haloalkane dehalogenase Rv2579 from Mycobacterium tuberculosis complexed with 1,3-propandiol 分子名称: 1,3-PROPANDIOL, BROMIDE ION, Haloalkane dehalogenase 3 著者 Mazumdar, P.A, Hulecki, J, Cherney, M.M, Garen, C.R, James, M.N.G, TB Structural Genomics Consortium (TBSGC) 登録日 2006-11-29 公開日 2007-11-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of haloalkane dehalogenase Rv2579 from Mycobacterium tuberculosis complexed with 1,3-propandiol To be Published
1Y1N	Identification of SH3 motif in M. Tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome 分子名称: Methionine aminopeptidase 1B, POTASSIUM ION 著者 Addlagatta, A, Quillin, M.L, Omotoso, O, Liu, J.O, Matthews, B.W. 登録日 2004-11-18 公開日 2005-05-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome Biochemistry, 44, 2005
2Q1X	Crystal Structure of cell division protein FtsZ from Mycobacterium tuberculosis in complex with citrate. 分子名称: CITRIC ACID, Cell division protein ftsZ 著者 Truglio, J.J. 登録日 2007-05-25 公開日 2008-05-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Identification of FtsZ Polymerization Regulatory Elements Using a Mycobacterium tuberculosis FtsZ Temperature Sensitive Mutant To be Published
3L21	The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (DAPA, RV2753C) from Mycobacterium Tuberculosis - DHDPS-A204R 分子名称: ACETATE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Evans, G.L, Schuldt, L, Jamerson, G.B, Devenish, S.R, Weiss, M.S, Gerrard, J.A. 登録日 2009-12-14 公開日 2010-12-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A dimeric mutant of DHDPS from Mycobacterium tuberculosis To be Published
2Q1Y	Crystal Structure of cell division protein FtsZ from Mycobacterium tuberculosis in complex with GTP-gamma-S 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell division protein ftsZ 著者 Truglio, J.J. 登録日 2007-05-25 公開日 2008-05-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Identification of FtsZ Polymerization Regulatory Elements Using a Mycobacterium tuberculosis FtsZ Temperature Sensitive Mutant To be Published
2QRW	Crystal structure of Mycobacterium tuberculosis trHbO WG8F mutant 分子名称: CYANIDE ION, Hemoglobin-like protein HbO, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Milani, M, Bolognesi, M. 登録日 2007-07-30 公開日 2007-11-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 The Roles of Tyr(CD1) and Trp(G8) in Mycobacterium tuberculosis Truncated Hemoglobin O in Ligand Binding and on the Heme Distal Site Architecture Biochemistry, 46, 2007
3IQA	Crystal Structure of BlaC covalently bound with Doripenem 分子名称: (2S,3R,4S)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase, PHOSPHATE ION 著者 Tremblay, L.W, Blanchard, J.S. 登録日 2009-08-19 公開日 2010-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Biochemical and structural characterization of Mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem. Biochemistry, 49, 2010

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