6WYN
Transition metal inhibition and structural refinement of the M. tuberculosis esterase, Rv0045c
Summary for 6WYN
| Entry DOI | 10.2210/pdb6wyn/pdb |
| Related | 6WYM |
| Descriptor | Possible hydrolase, CHLORIDE ION (3 entities in total) |
| Functional Keywords | serine esterase, allosteric regulation, conformational change, hydrolase |
| Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Total number of polymer chains | 1 |
| Total formula weight | 35625.24 |
| Authors | Macbeth, M.R.,Johnson, R.J.,Hoops, G.C. (deposition date: 2020-05-13, release date: 2021-05-19, Last modification date: 2023-10-18) |
| Primary citation | Bowles, I.E.,Pool, E.H.,Lancaster, B.S.,Lawson, E.K.,Savas, C.P.,Kartje, Z.J.,Severinac, L.,Cho, D.H.,Macbeth, M.R.,Johnson, R.J.,Hoops, G.C. Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045C. Protein Sci., 30:1554-1565, 2021 Cited by PubMed: 33914998DOI: 10.1002/pro.4089 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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