6WYN

Transition metal inhibition and structural refinement of the M. tuberculosis esterase, Rv0045c

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016787	molecular_function	hydrolase activity
A	0052689	molecular_function	carboxylic ester hydrolase activity
A	0106435	molecular_function	carboxylesterase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue CL A 401

Chain	Residue
A	GLY90
A	SER154
A	LEU155

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"21637775","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25354081","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PubMed","id":"25354081","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PubMed","id":"21637775","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25354081","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Involved in substrate selectivity","evidences":[{"source":"PubMed","id":"25354081","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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