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8DC4
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BU of 8dc4 by Molmil
Crystal structure of p53 Y220C covalently bound to carbazole KG3
分子名称: 9-propanoyl-9H-carbazole-3-carbaldehyde, bound form, Cellular tumor antigen p53, ...
著者Guiley, K.Z, Shokat, K.M.
登録日2022-06-15
公開日2022-10-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability.
Cancer Discov, 13, 2023
7LR1
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BU of 7lr1 by Molmil
Crystal structure of GH5_18 from Bifidobacterium longum subsp. longum ATCC 55813
分子名称: 1,2-ETHANEDIOL, Glycosyl hydrolase BlGH5_18, PHOSPHATE ION
著者Higgins, M.A, Ryan, K.S.
登録日2021-02-15
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes.
Acs Chem.Biol., 16, 2021
8ONJ
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BU of 8onj by Molmil
Crystal structure of D-amino acid aminotransferase from Aminobacterium colombiense point mutant R88L
分子名称: Aminotransferase class IV, DI(HYDROXYETHYL)ETHER, PYRIDOXAL-5'-PHOSPHATE
著者Matyuta, I.O, Boyko, K.M, Minyaev, M.E, Shilova, S.A, Bezsudnova, E.Y, Popov, V.O.
登録日2023-04-03
公開日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献In search for structural targets for engineering d-amino acid transaminase: modulation of pH optimum and substrate specificity.
Biochem.J., 480, 2023
8DCG
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BU of 8dcg by Molmil
Structure of guanylylated RNA ligase RtcB from Pyrococcus horikoshii
分子名称: CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION, ...
著者Jacewicz, A, Dantuluri, S, Shuman, S.
登録日2022-06-16
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
7LR8
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BU of 7lr8 by Molmil
Crystal structure of GH5_18-E153A from Streptomyces cattleya in complex with Manb1-4GlcNAc
分子名称: 1,2-ETHANEDIOL, 2-(2-ETHOXYETHOXY)ETHANOL, SULFATE ION, ...
著者Higgins, M.A, Ryan, K.S.
登録日2021-02-16
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes.
Acs Chem.Biol., 16, 2021
6URC
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BU of 6urc by Molmil
Crystal structure of IRE1a in complex with compound 18
分子名称: 2-chloro-N-(6-methyl-5-{[3-(2-{[(3S)-piperidin-3-yl]amino}pyrimidin-4-yl)pyridin-2-yl]oxy}naphthalen-1-yl)benzene-1-sulfonamide, GLYCEROL, Serine/threonine-protein kinase/endoribonuclease IRE1
著者Wallweber, H.H, Wang, W.
登録日2019-10-23
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Disruption of IRE1 alpha through its kinase domain attenuates multiple myeloma.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8P4C
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BU of 8p4c by Molmil
Structural insights into human co-transcriptional capping - structure 3
分子名称: DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ...
著者Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P.
登録日2023-05-20
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
8DCB
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BU of 8dcb by Molmil
RNA ligase RtcB from Pyrococcus horikoshii in complex with Ni2+ and GTP
分子名称: CHLORIDE ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Jacewicz, A, Dantuluri, S, Shuman, S.
登録日2022-06-16
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
7L9C
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BU of 7l9c by Molmil
Receiver Domain of RssB
分子名称: Regulator of RpoS
著者Deaconescu, A.M, Son, J, Schwartz, J.
登録日2021-01-03
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Phospho-dependent signaling during the general stress response by the atypical response regulator and ClpXP adaptor RssB.
Protein Sci., 30, 2021
7LIZ
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BU of 7liz by Molmil
LR6 rod linker and scaffolded phycoerythrin beta subunits from the phycobilisome of Porphyridium purpureum
分子名称: B-phycoerythrin beta chain, LR6, PHYCOERYTHROBILIN
著者Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G.
登録日2021-01-28
公開日2021-04-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
7LCM
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BU of 7lcm by Molmil
Receiver Domain of RssB bound to beryllofluoride
分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Regulator of RpoS
著者Deaconescu, A.M, Schwartz, J, Son, J.
登録日2021-01-11
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Phospho-dependent signaling during the general stress response by the atypical response regulator and ClpXP adaptor RssB.
Protein Sci., 30, 2021
6UUS
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BU of 6uus by Molmil
CryoEM Structure of the active Adrenomedullin 2 receptor G protein complex with adrenomedullin peptide
分子名称: ADM, Calcitonin gene-related peptide type 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R.
登録日2019-10-31
公開日2020-04-01
最終更新日2020-04-29
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structure and Dynamics of Adrenomedullin Receptors AM1and AM2Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins.
Acs Pharmacol Transl Sci, 3, 2020
7LJ0
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BU of 7lj0 by Molmil
Linker 3 and scaffolded phycoerythrin beta subunit from the phycobilisome of Porphyridium purpureum
分子名称: B-phycoerythrin beta chain, Linker 3, PHYCOERYTHROBILIN
著者Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G.
登録日2021-01-28
公開日2021-04-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
8DC7
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BU of 8dc7 by Molmil
Crystal structure of p53 Y220C covalently bound to indole KG10
分子名称: 4-[4-(4-methylpiperazin-1-yl)phenyl]-1-(2-methylprop-2-enoyl)-1H-indole-3-carbaldehyde, bound form, Cellular tumor antigen p53, ...
著者Guiley, K.Z, Shokat, K.M.
登録日2022-06-15
公開日2022-10-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9870069 Å)
主引用文献A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability.
Cancer Discov, 13, 2023
6UVA
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BU of 6uva by Molmil
CryoEM Structure of the active Adrenomedullin 2 receptor G protein complex with adrenomedullin 2 peptide
分子名称: Calcitonin gene-related peptide type 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R.
登録日2019-11-01
公開日2020-04-01
最終更新日2020-04-29
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structure and Dynamics of Adrenomedullin Receptors AM1and AM2Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins.
Acs Pharmacol Transl Sci, 3, 2020
7LR6
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BU of 7lr6 by Molmil
Crystal structure of GH5_18-E140A from Bifidobacterium longum subsp. longum ATCC 55813 in complex with Manb1-4GlcNAc
分子名称: Glycosyl hydrolase BlGH5_18, PHOSPHATE ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Higgins, M.A, Ryan, K.S.
登録日2021-02-16
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes.
Acs Chem.Biol., 16, 2021
8DCF
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BU of 8dcf by Molmil
RNA ligase RtcB from Pyrococcus horikoshii in complex with Cu2+ and GTP
分子名称: CHLORIDE ION, COPPER (II) ION, GLYCEROL, ...
著者Jacewicz, A, Dantuluri, S, Shuman, S.
登録日2022-06-16
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
6UTA
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BU of 6uta by Molmil
Crystal structure of Z004 iGL Fab in complex with ZIKV EDIII
分子名称: Env, Z004 iGL Fab heavy chain, Z004 iGL Fab light chain
著者Esswein, S.R, Gristick, H.B, Keeffe, J.R, Bjorkman, P.J.
登録日2019-10-29
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 117, 2020
8DC8
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BU of 8dc8 by Molmil
Crystal structure of p53 Y220C covalently bound to azaindole KG13
分子名称: 2-methyl-1-[(4P)-3-methyl-4-(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]prop-2-en-1-one, bound form, Cellular tumor antigen p53, ...
著者Guiley, K.Z, Shokat, K.M.
登録日2022-06-15
公開日2022-10-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7200973 Å)
主引用文献A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability.
Cancer Discov, 13, 2023
7LSG
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BU of 7lsg by Molmil
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Siberian Subtype)
分子名称: Core protein, T025 Fab Heavy Chain, T025 Fab Light Chain
著者Keeffe, J.R, Bjorkman, P.J.
登録日2021-02-18
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
J.Exp.Med., 218, 2021
7LIY
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BU of 7liy by Molmil
CaRSP2 and scaffolded phycoerythrin beta subunits from the phycobilisome of Porphyridium purpureum
分子名称: B-phycoerythrin beta chain, CaRSP2, PHYCOERYTHROBILIN
著者Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G.
登録日2021-01-28
公開日2021-04-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
7LIP
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BU of 7lip by Molmil
X-ray structure of SPOP MATH domain (D140G)
分子名称: SULFATE ION, Speckle-type POZ protein
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
8DFI
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BU of 8dfi by Molmil
Crystal structure of moderately neutralizing / interfering human monoclonal antibody 42C11 Fab in complex with MSP1-19
分子名称: 42C11 Fab Heavy Chain, 42C11 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
6UWR
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BU of 6uwr by Molmil
Clostridium difficile binary toxin translocase CDTb in asymmetric tetradecamer conformation
分子名称: ADP-ribosyltransferase binding component, CALCIUM ION
著者Xu, X, Pozharski, E, des Georges, A.
登録日2019-11-05
公開日2020-01-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.
Proc.Natl.Acad.Sci.USA, 117, 2020
7SHG
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BU of 7shg by Molmil
Polysaccharide ribofuranosyl transferase from Thermobacillus composti
分子名称: CHLORIDE ION, MAGNESIUM ION, Ribofuranosyl transferase
著者Kimber, M.S, Kelly, S.D.
登録日2021-10-08
公開日2022-03-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The biosynthetic origin of ribofuranose in bacterial polysaccharides.
Nat.Chem.Biol., 18, 2022

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件を2024-10-16に公開中

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