5TD8
| Crystal structure of an Extended Dwarf Ndc80 Complex | 分子名称: | Kinetochore protein NDC80, Kinetochore protein NUF2, Kinetochore protein SPC24, ... | 著者 | Valverde, R, Ingram, J, Harrison, S.C. | 登録日 | 2016-09-17 | 公開日 | 2016-11-16 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (7.531 Å) | 主引用文献 | Conserved Tetramer Junction in the Kinetochore Ndc80 Complex. Cell Rep, 17, 2016
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5TEF
| Crystal structure of Gemin5 WD40 repeats in complex with m7GpppG | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, GLYCEROL, Gem-associated protein 5, ... | 著者 | Chao, X, Tempel, W, Bian, C, He, H, Cerovina, T, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2016-09-21 | 公開日 | 2016-10-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly. Genes Dev., 30, 2016
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5TFR
| Crystal structure of Zika Virus NS5 protein | 分子名称: | Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | 著者 | Longenecker, K.L, Upadhyay, A.K. | 登録日 | 2016-09-26 | 公開日 | 2016-10-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5. Acta Crystallogr F Struct Biol Commun, 73, 2017
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5TIL
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5TJ2
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5TJR
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5SUU
| X-ray crystallographic structure of a covalent trimer derived from A-beta 17-36. X-ray diffractometer data set. (ORN)CVFFCED(ORN)AII(SAR)L(ORN)V. | 分子名称: | 16mer A-beta peptide: ORN-CYS-VAL-PHE-PHE-CYS-GLU-ASP-ORN-ALA-ILE-ILE-SAR-LEU-ORN-VAL, CHLORIDE ION, IODIDE ION | 著者 | Kreutzer, A.G, Spencer, R.K, Nowick, J.S. | 登録日 | 2016-08-03 | 公開日 | 2017-01-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | 主引用文献 | Stabilization, Assembly, and Toxicity of Trimers Derived from A beta. J.Am.Chem.Soc., 139, 2017
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5SUR
| X-ray crystallographic structure of a covalent trimer derived from A-beta 17_36. Synchrotron data set. (ORN)CVF(MEA)CED(ORN)AIIGL(ORN)V. | 分子名称: | 16mer A-beta peptide: ORN-CYS-VAL-PHE-MEA-CYS-GLU-ASP-ORN-ALA-ILE-ILE-GLY-LEU-ORN-VAL, CHLORIDE ION, HEXANE-1,6-DIOL, ... | 著者 | Kreutzer, A.G, Yoo, S, Nowick, J.S. | 登録日 | 2016-08-03 | 公開日 | 2017-01-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Stabilization, Assembly, and Toxicity of Trimers Derived from A beta. J.Am.Chem.Soc., 139, 2017
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5SUP
| Crystal structure of the Sub2-Yra1 complex in association with RNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase SUB2, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Ren, Y, Schmiege, P, Blobel, G. | 登録日 | 2016-08-03 | 公開日 | 2017-01-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1. Elife, 6, 2017
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5T6E
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5T6M
| Structure of the tryptophan synthase b-subunit from Pyroccus furiosus with b-methyltryptophan non-covalently bound | 分子名称: | (betaS)-beta-methyl-L-tryptophan, PHOSPHATE ION, SODIUM ION, ... | 著者 | Buller, A.R, van Roye, P, Arnold, F.H. | 登録日 | 2016-09-01 | 公開日 | 2016-12-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity. Biochemistry, 55, 2016
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5TBX
| hnRNP A18 RNA Recognition Motif | 分子名称: | ACETATE ION, Cold-inducible RNA-binding protein, NICKEL (II) ION | 著者 | Coburn, K.M, Melville, Z, Aligholizadeh, E, Roth, B.M, Varney, K.M, Weber, D.J. | 登録日 | 2016-09-13 | 公開日 | 2017-04-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.767 Å) | 主引用文献 | Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif. Acta Crystallogr F Struct Biol Commun, 73, 2017
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5TDN
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5TFU
| Structure of cytochrome P450 2D6 (CYP2D6) BACE1 inhibitor complex | 分子名称: | (4S,6R)-4-[2,4-difluoro-5-({[1-(trifluoromethyl)cyclopropyl]amino}methyl)phenyl]-4,6-dimethyl-5,6-dihydro-4H-1,3-thiazin-2-amine, Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Hsu, M.H, Johnson, E.F. | 登録日 | 2016-09-26 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality. J. Med. Chem., 60, 2017
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5THP
| Rhodocetin in complex with the integrin alpha2-A domain | 分子名称: | CHLORIDE ION, GLYCEROL, Integrin alpha-2, ... | 著者 | McDougall, M, Orriss, G.L, Stetefeld, J. | 登録日 | 2016-09-30 | 公開日 | 2017-08-02 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.006 Å) | 主引用文献 | Dramatic and concerted conformational changes enable rhodocetin to block alpha 2 beta 1 integrin selectively. PLoS Biol., 15, 2017
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5T63
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5T69
| The HhoA protease from Synechocystis sp. PCC 6803, active site mutant | 分子名称: | ACETATE ION, MAGNESIUM ION, Putative serine protease HhoA | 著者 | Persson, K, Hall, M, Funk, C. | 登録日 | 2016-09-01 | 公開日 | 2017-01-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The HhoA protease from Synechocystis sp. PCC 6803 - Novel insights into structure and activity regulation. J. Struct. Biol., 198, 2017
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5T6D
| 2.10 A resolution structure of Norovirus 3CL protease in complex with the dipeptidyl inhibitor 7l (hexagonal form) | 分子名称: | 3-cyclohexyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-N~2~-{[3-(4-methoxyphenoxy)propyl]sulfonyl}-L- alaninamide, Genome polyprotein | 著者 | Lovell, S, Battaile, K.P, Mehzabeen, N, Kankanamalage, A.C.G, Kim, Y, Rathnayake, A.D, Damalanka, V.C, Weerawarna, P.M, Doyle, S.T, Alsoudi, A.F, Dissanayake, D.M.P, Chang, K.-O, Groutas, W.C. | 登録日 | 2016-09-01 | 公開日 | 2016-11-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors. Eur J Med Chem, 126, 2016
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5T6J
| Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly | 分子名称: | Kinetochore protein SPC24, Kinetochore protein SPC25, Kinetochore-associated protein DSN1 | 著者 | Valverde, R, Jenni, S, Dimitrova, Y, Khin, Y, Harrison, S.C. | 登録日 | 2016-09-01 | 公開日 | 2016-11-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.752 Å) | 主引用文献 | Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly. Cell, 167, 2016
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5T5U
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5T8Q
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5T6F
| 1.90 A resolution structure of Norovirus 3CL protease in complex with the dipeptidyl inhibitor 7l (orthorhombic P form) | 分子名称: | 3-cyclohexyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-N~2~-{[3-(4-methoxyphenoxy)propyl]sulfonyl}-L- alaninamide, Genome polyprotein | 著者 | Lovell, S, Battaile, K.P, Mehzabeen, N, Kankanamalage, A.C.G, Kim, Y, Rathnayake, A.D, Damalanka, V.C, Weerawarna, P.M, Doyle, S.T, Alsoudi, A.F, Dissanayake, D.M.P, Chang, K.-O, Groutas, W.C. | 登録日 | 2016-09-01 | 公開日 | 2016-11-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors. Eur J Med Chem, 126, 2016
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5T7S
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5TBD
| Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222 | 分子名称: | Fv fragment (mAb4D1) heavy chain, Merozoite surface protein 2 | 著者 | Seow, J, Morales, R.A.V, MacRaild, C.A, Bankala, K, Drinkwater, N, Dingjan, T, Jaipuria, G, Wilde, K, Anders, R.F, Atreya, H.S, Christ, D, McGowan, S, Norton, R.S. | 登録日 | 2016-09-12 | 公開日 | 2017-02-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2. J. Mol. Biol., 429, 2017
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5TBP
| Crystal Structure of RXR-alpha ligand binding domain complexed with synthetic modulator K8003 | 分子名称: | ACETATE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Aleshin, A.E, Liddington, R.C, Su, Y, Zhang, X. | 登録日 | 2016-09-12 | 公開日 | 2017-08-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXR alpha. Nat Commun, 8, 2017
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