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3V9R
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Crystal structure of Saccharomyces cerevisiae MHF complex
分子名称: SULFATE ION, Uncharacterized protein YDL160C-A, Uncharacterized protein YOL086W-A
著者Yang, H, Zhang, T, Zhong, C, Li, H, Zhou, J, Ding, J.
登録日2011-12-28
公開日2012-02-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Saccharomyces Cerevisiae MHF Complex Structurally Resembles the Histones (H3-H4)(2) Heterotetramer and Functions as a Heterotetramer
Structure, 20, 2012
2J3T
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The crystal structure of the bet3-trs33-bet5-trs23 complex.
分子名称: PALMITIC ACID, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3, ...
著者Kim, Y, Oh, B.
登録日2006-08-23
公開日2006-11-22
最終更新日2011-10-26
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Architecture of the Multisubunit Trapp I Complex Suggests a Model for Vesicle Tethering.
Cell(Cambridge,Mass.), 127, 2006
1NYD
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Solution structure of DNA quadruplex GCGGTGGAT
分子名称: 5'-D(*GP*CP*GP*GP*TP*GP*GP*AP*T)-3'
著者Webba da Silva, M.
登録日2003-02-12
公開日2004-02-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Association of DNA quadruplexes through G:C:G:C tetrads. Solution structure of d(GCGGTGGAT).
Biochemistry, 42, 2003
7WU5
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Cryo-EM structure of the adhesion GPCR ADGRF1(H565A/T567A) in complex with miniGi
分子名称: Adhesion G-protein coupled receptor F1, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B.
登録日2022-02-05
公開日2022-04-27
最終更新日2022-05-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1.
Nature, 604, 2022
7WU4
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Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with miniGi
分子名称: Adhesion G-protein coupled receptor F1, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B.
登録日2022-02-05
公開日2022-04-27
最終更新日2022-05-11
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1.
Nature, 604, 2022
3VD7
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E. coli (lacZ) beta-galactosidase (N460S) in complex with galactotetrazole
分子名称: (5R, 6S, 7S, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
1Y76
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Solution Structure of Patj/Pals1 L27 Domain Complex
分子名称: MAGUK p55 subfamily member 5, protein associated to tight junctions
著者Feng, W, Long, J.-F, Zhang, M.
登録日2004-12-08
公開日2005-04-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1Y74
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Solution Structure of mLin-2/mLin-7 L27 Domain Complex
分子名称: Peripheral plasma membrane protein CASK, lin 7 homolog b
著者Feng, W, Long, J.-F, Zhang, M.
登録日2004-12-08
公開日2005-04-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1V3O
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Crystal structure of d(GCGAGAGC): the DNA quadruplex structure split from the octaplex
分子名称: 5'-D(*GP*(C38)P*GP*AP*GP*AP*GP*C)-3', POTASSIUM ION
著者Kondo, J, Umeda, S, Sunami, T, Takenaka, A.
登録日2003-11-03
公開日2004-06-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of a DNA octaplex with I-motif of G-quartets and its splitting into two quadruplexes suggest a folding mechanism of eight tandem repeats
Nucleic Acids Res., 32, 2004
1V3N
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Crystal structure of d(GCGAGAGC): the DNA quadruplex structure split from the octaplex
分子名称: 5'-D(*GP*(CBR)P*GP*AP*GP*AP*GP*C)-3', POTASSIUM ION
著者Kondo, J, Umeda, S, Sunami, T, Takenaka, A.
登録日2003-11-03
公開日2004-06-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of a DNA octaplex with I-motif of G-quartets and its splitting into two quadruplexes suggest a folding mechanism of eight tandem repeats
Nucleic Acids Res., 32, 2004
1QX8
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Crystal structure of a five-residue deletion mutant of the Rop protein
分子名称: Regulatory protein ROP
著者Glykos, N.M, Vlassi, M, Papanikolaou, Y, Kotsifaki, D, Cesareni, G, Kokkinidis, M.
登録日2003-09-04
公開日2004-09-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Loopless Rop: structure and dynamics of an engineered homotetrameric variant of the repressor of primer protein.
Biochemistry, 45, 2006
6X4N
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Human cyclophilin A bound to a series of acylcic and macrocyclic inhibitors: (2R,5S,11S,14S,18E)-2,11,17,17-tetramethyl-14-(propan-2-yl)-3-oxa-9,12,15,26,29-pentaazatetracyclo[18.5.3.1~5,9~.0~23,27~]nonacosa-1(25),18,20(28),21,23,26-hexaene-4,10,13,16-tetrone (compound 24)
分子名称: (2R,5S,11S,14S,18E)-2,11,17,17-tetramethyl-14-(propan-2-yl)-3-oxa-9,12,15,26,29-pentaazatetracyclo[18.5.3.1~5,9~.0~23,27~]nonacosa-1(25),18,20(28),21,23,26-hexaene-4,10,13,16-tetrone, Peptidyl-prolyl cis-trans isomerase A
著者Appleby, T.C, Paulsen, J.L, Schmitz, U, Shivakumar, D.
登録日2020-05-22
公開日2020-06-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Evaluation of Free Energy Calculations for the Prioritization of Macrocycle Synthesis.
J.Chem.Inf.Model., 60, 2020
6X4P
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Human cyclophilin A bound to a series of acylcic and macrocyclic inhibitors: (2R,5S,11S,14S,18E)-2,11,17,17-tetramethyl-14-(propan-2-yl)-15-oxa-3,9,12,26,29-pentaazatetracyclo[18.5.3.1~5,9~.0~23,27~]nonacosa-1(25),18,20(28),21,23,26-hexaene-4,10,13,16-tetrone (compound 28)
分子名称: (2R,5S,11S,14S,18E)-2,11,17,17-tetramethyl-14-(propan-2-yl)-15-oxa-3,9,12,26,29-pentaazatetracyclo[18.5.3.1~5,9~.0~23,27~]nonacosa-1(25),18,20(28),21,23,26-hexaene-4,10,13,16-tetrone, Peptidyl-prolyl cis-trans isomerase A
著者Appleby, T.C, Paulsen, J.L, Schmitz, U, Shivakumar, D.
登録日2020-05-22
公開日2020-06-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Evaluation of Free Energy Calculations for the Prioritization of Macrocycle Synthesis.
J.Chem.Inf.Model., 60, 2020
6X4Q
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Human cyclophilin A bound to a series of acylcic and macrocyclic inhibitors: (2R,5S,11S,14S,18E)-14-cyclobutyl-2,11,17,17-tetramethyl-15-oxa-3,9,12,26,29-pentaazatetracyclo[18.5.3.1~5,9~.0~23,27~]nonacosa-1(25),18,20(28),21,23,26-hexaene-4,10,13,16-tetrone (compound 33)
分子名称: (2R,5S,11S,14S,18E)-14-cyclobutyl-2,11,17,17-tetramethyl-15-oxa-3,9,12,26,29-pentaazatetracyclo[18.5.3.1~5,9~.0~23,27~]nonacosa-1(25),18,20(28),21,23,26-hexaene-4,10,13,16-tetrone, Peptidyl-prolyl cis-trans isomerase A
著者Appleby, T.C, Paulsen, J.L, Schmitz, U, Shivakumar, D.
登録日2020-05-22
公開日2020-06-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Evaluation of Free Energy Calculations for the Prioritization of Macrocycle Synthesis.
J.Chem.Inf.Model., 60, 2020
1RWO
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Crystal structure of human caspase-1 in complex with 4-oxo-3-{6-[4-(quinoxalin-2-ylamino)-benzoylamino]-2-thiophen-2-yl-hexanoylamino}-pentanoic acid
分子名称: 4-OXO-3-{6-[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-PENTANOIC ACID, Interleukin-1 beta convertase
著者Romanowski, M.J, Waal, N.D, Fahr, B.T, O'Brien, T.
登録日2003-12-16
公開日2004-12-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWN
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Crystal structure of human caspase-1 in complex with 3-{2-ethyl-6-[4-(quinoxalin-2-ylamino)-benzoylamino]-hexanoylamino}-4-oxo-butyric acid
分子名称: 3-{2-ETHYL-6-[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-HEXANOYLAMINO}-4-OXO-BUTYRIC ACID, Interleukin-1 beta convertase
著者Romanowski, M.J, Fahr, B.T, O'Brien, T.
登録日2003-12-16
公開日2004-12-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWM
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Crystal structure of human caspase-1 in complex with 4-oxo-3-[2-(5-{[4-(quinoxalin-2-ylamino)-benzoylamino]-methyl}-thiophen-2-yl)-acetylamino]-pentanoic acid
分子名称: 4-OXO-3-[2-(5-{[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-METHYL}-THIOPHEN-2-YL)-ACETYLAMINO]-PENTANOIC ACID, Interleukin-1 beta convertase
著者Romanowski, M.J, Waal, N.D, Fahr, B.T, O'Brien, T.
登録日2003-12-16
公開日2004-12-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWP
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Crystal structure of human caspase-1 in complex with 3-{6-[(8-hydroxy-quinoline-2-carbonyl)-amino]-2-thiophen-2-yl-hexanoylamino}-4-oxo-butyric acid
分子名称: 3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID, Interleukin-1 beta convertase
著者Romanowski, M.J, Fahr, B.T, O'Brien, T.
登録日2003-12-16
公開日2004-12-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWK
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Crystal structure of human caspase-1 in complex with 3-(2-mercapto-acetylamino)-4-oxo-pentanoic acid
分子名称: 3-(2-MERCAPTO-ACETYLAMINO)-4-OXO-PENTANOIC ACID, Interleukin-1 beta convertase
著者Romanowski, M.J, Lam, J.W, Fahr, B.T, O'Brien, T.
登録日2003-12-16
公開日2004-12-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1XOE
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N9 Tern influenza neuraminidase complexed with (2R,4R,5R)-5-(1-Acetylamino-3-methyl-butyl-pyrrolidine-2, 4-dicarobyxylic acid 4-methyl esterdase complexed with
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-4-(METHOXYCARBONYL)PROLINE, Neuraminidase, ...
著者Wang, G.T, Wang, S, Gentles, R, Sowin, T, Maring, C.J, Kempf, D.J, Kati, W.M, Stoll, V, Stewart, K.D, Laver, G.
登録日2004-10-06
公開日2005-01-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core.
Bioorg.Med.Chem.Lett., 15, 2005
1VAR
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BU of 1var by Molmil
MITOCHONDRIAL MANGANESE SUPEROXIDE DISMUTASE VARIANT WITH ILE 58 REPLACED BY THR
分子名称: MANGANESE (III) ION, MANGANESE SUPEROXIDE DISMUTASE
著者Borgstahl, G.E.O, Parge, H.E, Tainer, J.A.
登録日1996-01-04
公開日1996-06-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface.
Biochemistry, 35, 1996
1OU6
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Biosynthetic thiolase from Zoogloea ramigera in complex with acetyl-O-pantetheine-11-pivalate
分子名称: Acetyl-CoA acetyltransferase, PANTOTHENYL-AMINOETHANOL-ACETATE PIVALIC ACID, SULFATE ION
著者Kursula, P, Schmitz, W, Wierenga, R.K.
登録日2003-03-24
公開日2004-06-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The surprising binding mode of a coenzyme A analogue, O-pantetheine-11-pivalate, in the catalytic cavity of bacterial biosynthetic thiolase
To be Published
1TT0
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Crystal Structure of Pyranose 2-Oxidase
分子名称: ACETATE ION, DODECAETHYLENE GLYCOL, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Hallberg, B.M, Leitner, C, Haltrich, D, Divne, C.
登録日2004-06-21
公開日2005-06-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the 270 kDa homotetrameric lignin-degrading enzyme pyranose 2-oxidase
J.Mol.Biol., 341, 2004
1SN0
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Crystal Structure Of Sea Bream Transthyretin in complex with thyroxine At 1.9A Resolution
分子名称: 3,5,3',5'-TETRAIODO-L-THYRONINE, SULFATE ION, transthyretin
著者Eneqvist, T, Lundberg, E, Karlsson, A, Huang, S, Santos, C.R, Power, D.M, Sauer-Eriksson, A.E.
登録日2004-03-10
公開日2004-08-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High resolution crystal structures of piscine transthyretin reveal different binding modes for triiodothyronine and thyroxine.
J.Biol.Chem., 279, 2004
1SQL
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Crystal structure of 7,8-dihydroneopterin aldolase in complex with guanine
分子名称: GUANINE, dihydroneopterin aldolase
著者Bauer, S, Schott, A.K, Illarionova, V, Bacher, A, Huber, R, Fischer, M.
登録日2004-03-19
公開日2004-06-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Biosynthesis of Tetrahydrofolate in Plants: Crystal Structure of 7,8-Dihydroneopterin Aldolase from Arabidopsis thaliana Reveals a Novel Adolase Class.
J.Mol.Biol., 339, 2004

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