PDB: 35756 件ウェブページステータス検索Chemie searchBIRD

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4KTL	Crystal structure of Mycobacterium tuberculosis CYP121 in complex with 4,4'-(3-((4-hydroxyphenyl)amino)-1H-pyrazole-4,5-diyl)diphenol 分子名称: 4,4'-{3-[(4-hydroxyphenyl)amino]-1H-pyrazole-4,5-diyl}diphenol, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Hudson, S.A. 登録日 2013-05-20 公開日 2013-07-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting Mycobacterium tuberculosis CYP121. Chemmedchem, 8, 2013
6IMI	Crystal structure of PDE4D complexed with a novel inhibitor 分子名称: 1,2-ETHANEDIOL, 6-ethoxy-7-methoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ... 著者 Zhang, X, Su, H, Xu, Y. 登録日 2018-10-23 公開日 2019-10-23 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent. J.Med.Chem., 62, 2019
4TTG	Beta-galactosidase (E. coli) in the presence of potassium chloride. 分子名称: Beta-galactosidase, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Juers, D.H. 登録日 2014-06-20 公開日 2015-03-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Elucidating factors important for monovalent cation selectivity in enzymes: E. coli beta-galactosidase as a model. Phys Chem Chem Phys, 17, 2015
6FZB	AadA in complex with ATP, magnesium and streptomycin 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Kanchugal P, S, Selmer, M. 登録日 2018-03-14 公開日 2018-06-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase fromSalmonella enterica. J. Biol. Chem., 293, 2018
7XNT	Crystal structure of PfHPPD-Y13161 complex 分子名称: 3-(2,6-dimethylphenyl)-1-methyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION 著者 Lin, H.-Y, Yang, G.-F. 登録日 2022-04-29 公開日 2022-12-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.822 Å) 主引用文献 Structural insights of 4-Hydrophenylpyruvate dioxygenase inhibition by structurally diverse small molecules Adv Agrochem, 2022
5Z5H	Crystal structure of a thermostable glycoside hydrolase family 43 {beta}-1,4-xylosidase from Geobacillus thermoleovorans IT-08 in complex with D-xylose 分子名称: Beta-xylosidase, CALCIUM ION, alpha-D-xylopyranose 著者 Rohman, A, van Oosterwijk, N, Puspaningsih, N.N.T, Dijkstra, B.W. 登録日 2018-01-18 公開日 2018-04-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis of product inhibition by arabinose and xylose of the thermostable GH43 beta-1,4-xylosidase from Geobacillus thermoleovorans IT-08. PLoS ONE, 13, 2018
7XMC	Cryo-EM structure of Cytochrome bo3 from Escherichia coli, apo structure with DMSO 分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... 著者 Nishida, Y, Shigematsu, H, Iwamoto, T, Takashima, S, Shintani, Y. 登録日 2022-04-25 公開日 2022-12-21 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat Commun, 13, 2022
2V3F	acid-beta-glucosidase produced in carrot 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUCOSYLCERAMIDASE, SULFATE ION, ... 著者 Shaaltiel, Y, Bartfeld, D, Hashmueli, S, Baum, G, Brill-Almon, E, Galili, G, Dym, O, Boldin-Adamsky, S.A, Silman, I, Sussman, J.L, Futerman, A.H, Aviezer, D, Israel Structural Proteomics Center (ISPC) 登録日 2007-06-17 公開日 2008-04-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Production of Glucocerebrosidase with Terminal Mannose Glycans for Enzyme Replacement Therapy of Gaucher'S Disease Using a Plant Cell System. Plant Biotechnol.J., 5, 2007
6BW4	Crystal structure of RBBP4 in complex with PRDM16 N-terminal peptide 分子名称: Histone-binding protein RBBP4, PR domain zinc finger protein 16, UNKNOWN ATOM OR ION 著者 Ivanochko, D, Halabelian, L, Hutchinson, A, Seitova, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) 登録日 2017-12-14 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex. Nucleic Acids Res., 47, 2019
3FI9	Crystal structure of malate dehydrogenase from Porphyromonas gingivalis 分子名称: Malate dehydrogenase 著者 Bonanno, J.B, Freeman, J, Bain, K.T, Miller, S, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2008-12-11 公開日 2008-12-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of malate dehydrogenase from Porphyromonas gingivalis To be Published
4KRW	Novel re-arrangement of an RsmA/cSRa family protein to create a structurally distinct new RNA-binding family member 分子名称: IODIDE ION, RsmN, a RNA-binding protein of Regulator of Secondary Metabolism 著者 Li, C. 登録日 2013-05-17 公開日 2013-09-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural Rearrangement in an RsmA/CsrA Ortholog of Pseudomonas aeruginosa Creates a Dimeric RNA-Binding Protein, RsmN. Structure, 21, 2013
7XMD	Cryo-EM structure of Cytochrome bo3 from Escherichia coli, the structure complexed with an allosteric inhibitor N4 分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... 著者 Nishida, Y, Shigematsu, H, Iwamoto, T, Takashima, S, Shintani, Y. 登録日 2022-04-25 公開日 2022-12-21 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.99 Å) 主引用文献 Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat Commun, 13, 2022
3I44	Crystal structure of aldehyde dehydrogenase from bartonella henselae at 2.0A resolution 分子名称: Aldehyde dehydrogenase, SODIUM ION, UNKNOWN ATOM OR ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-07-01 公開日 2009-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of aldehyde dehydrogenase from bartonella henselae at 2.0A resolution To be Published
7WYG	Crystal structure of P450BSbeta-L78I/Q85H/G290I variant in complex with palmitic acid. 分子名称: Cytochrome P450 152A1, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Li, F, He, C, Wang, X. 登録日 2022-02-16 公開日 2022-12-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biocatalytic Enantioselective beta-Hydroxylation of Unactivated C-H Bonds in Aliphatic Carboxylic Acids. Angew.Chem.Int.Ed.Engl., 61, 2022
6FY4	Structure of human NAD(P) H:quinone oxidoreductase in complex with N-(2-bromophenyl)pyrrolidine-1-sulfonamide 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N-(2-bromophenyl)pyrrolidine-1-sulfonamide, NAD(P)H dehydrogenase [quinone] 1 著者 Gruber, K, Hromic, A. 登録日 2018-03-10 公開日 2019-03-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 A small molecule chaperone rescues the stability and activity of a cancer-associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro. Febs Lett., 594, 2020
6C5Z	Human UDP-Glucose Dehydrogenase A225L substitutuion with UDP-glucose and NADH bound 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-GLUCOSE 著者 Gross, P.G, Sidlo, A.M, Walsh, R.M, Peeples, W.B, Wood, Z.A. 登録日 2018-01-17 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 The A225L Substitution of hUGDH alters structure and function To Be Published
3FJN	The crystal structure of 17-alpha hydroxysteroid dehydrogenase Y224D mutant. 分子名称: ACETATE ION, Aldo-keto reductase family 1 member C21 著者 Dhagat, U, El-Kabbani, O. 登録日 2008-12-14 公開日 2009-11-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme Acta Crystallogr.,Sect.D, 66, 2010
2VFS	Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Xylitol 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, XYLITOL OXIDASE, ... 著者 Forneris, F, Mattevi, A. 登録日 2007-11-05 公開日 2008-01-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase. Biochemistry, 47, 2008
5ZC2	Acinetobacter baumannii p-hydroxyphenylacetate 3-hydroxylase (HPAH), reductase component (C1) 分子名称: FLAVIN MONONUCLEOTIDE, p-hydroxyphenylacetate 3-hydroxylase, reductase component 著者 Yuenyao, A, Petchyam, N, Chaiyen, P, Pakotiprapha, D. 登録日 2018-02-14 公開日 2018-08-08 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.898 Å) 主引用文献 Crystal structure of the flavin reductase of Acinetobacter baumannii p-hydroxyphenylacetate 3-hydroxylase (HPAH) and identification of amino acid residues underlying its regulation by aromatic ligands Arch. Biochem. Biophys., 653, 2018
7RLU	Structure of ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP 分子名称: 4'-PHOSPHOPANTETHEINE, Cytosolic 10-formyltetrahydrofolate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Tsybovsky, Y, Sereda, V, Golczak, M, Krupenko, N.I, Krupenko, S.A. 登録日 2021-07-26 公開日 2022-01-12 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure of putative tumor suppressor ALDH1L1. Commun Biol, 5, 2022
5Z19	The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine 分子名称: (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, Beta-glucuronidase 著者 Dashnyam, P, Lin, H.Y, Lin, C.H. 登録日 2017-12-25 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Dissection of the substrate preference and structure of gut microbial beta-glucuronidases identifies the major bacteria causing xenobiotic toxicity To Be Published
4KTJ	Crystal structure of Mycobacterium tuberculosis CYP121 in complex with 4-(3-amino-1H-pyrazol-4-yl)phenol 分子名称: 4-(3-amino-1H-pyrazol-4-yl)phenol, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Hudson, S.A. 登録日 2013-05-20 公開日 2013-07-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting Mycobacterium tuberculosis CYP121. Chemmedchem, 8, 2013
6IQ6	Crystal structure of GAPDH 分子名称: (2Z)-4-methoxy-4-oxobut-2-enoic acid, Glyceraldehyde-3-phosphate dehydrogenase 著者 Park, J.B, Park, H.Y. 登録日 2018-11-06 公開日 2019-08-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural Study of Monomethyl Fumarate-Bound Human GAPDH. Mol.Cells, 42, 2019
3FKE	Structure of the Ebola VP35 Interferon Inhibitory Domain 分子名称: Polymerase cofactor VP35 著者 Amarasinghe, G.K, Leung, D.W, Ginder, N.D, Honzatko, R.B, Nix, J, Basler, C.F, Fulton, D.B. 登録日 2008-12-16 公開日 2009-01-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure of the Ebola VP35 interferon inhibitory domain. Proc.Natl.Acad.Sci.USA, 106, 2009
4KTO	Crystal Structure Of a Putative Isovaleryl-CoA dehydrogenase (PSI-NYSGRC-012251) from Sinorhizobium meliloti 1021 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, isovaleryl-CoA dehydrogenase 著者 Kumar, P.R, Ahmed, M, Attonito, J, Bhosle, R, Bonanno, J, Chamala, S, Chowdhury, S, Glenn, A.S, Hammonds, J, Hillerich, B, Himmel, D, Love, J.D, Seidel, R, Stead, M, Toro, R, Wasserman, S.R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-05-20 公開日 2013-06-19 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.137 Å) 主引用文献 Crystal structure of a Putative Isovaleryl-CoA dehydrogenase from Sinorhizobium meliloti 1021 to be published

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