PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

---

3G4M	Crystal structure of guanine riboswitch bound to 2-aminopurine 分子名称: 9H-purin-2-amine, ACETATE ION, COBALT HEXAMMINE(III), ... 著者 Gilbert, S.D, Batey, R.T. 登録日 2009-02-04 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Adaptive ligand binding by the purine riboswitch in the recognition of Guanine and adenine analogs. Structure, 17, 2009
6ANU	Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain 分子名称: Actin, cytoplasmic 1, Spectrin beta chain, ... 著者 Wang, F, Orlova, A, Avery, A.W, Hays, T.S, Egelman, E.H. 登録日 2017-08-14 公開日 2017-11-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Structural basis for high-affinity actin binding revealed by a beta-III-spectrin SCA5 missense mutation. Nat Commun, 8, 2017
3SR4	Crystal Structure of Human DOT1L in Complex with a Selective Inhibitor 分子名称: (2S)-2-azanyl-4-[[(2S,3S,4R,5R)-5-[6-(methylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, ACETATE ION, GLYCEROL, ... 著者 Diao, J, Chen, P, Yao, Y, Prasad, B.V.V, Song, Y. 登録日 2011-07-06 公開日 2011-10-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies. J.Am.Chem.Soc., 133, 2011
6AQR	SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin 分子名称: Polyubiquitin-C, SAGA-associated factor 11, SAGA-associated factor 73, ... 著者 Morrow, M.E, Morgan, M.T, Wolberger, C. 登録日 2017-08-21 公開日 2018-07-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins. EMBO Rep., 19, 2018
3FWO	The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin 分子名称: (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA 著者 Auerbach, T, Mermershtain, I, Bashan, A, Davidovich, C, Rozenberg, H, Sherman, D.H, Yonath, A. 登録日 2009-01-19 公開日 2010-01-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.71 Å) 主引用文献 Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin Biotechnologia, 1, 2009
3SAF	Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site 分子名称: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION 著者 Januszyk, K, Liu, Q, Lima, C.D. 登録日 2011-06-02 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
6B30	Structure of RORgt in complex with a novel inverse agonist 1 分子名称: N-[(1R)-1-(4-methoxyphenyl)-2-oxo-2-{[4-(trimethylsilyl)phenyl]amino}ethyl]-N-methyl-3-oxo-2,3-dihydro-1,2-oxazole-5-carboxamide, Nuclear receptor ROR-gamma 著者 Skene, R.J, Hoffman, I. 登録日 2017-09-20 公開日 2018-01-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Discovery of orally efficacious ROR gamma t inverse agonists, part 1: Identification of novel phenylglycinamides as lead scaffolds. Bioorg. Med. Chem., 26, 2018
6AN1	Crystal structure of the complex between PPARgamma LBD and the ligand AM-879 分子名称: 4-({2-[(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)methyl]phenoxy}methyl)benzoic acid, Peroxisome proliferator-activated receptor gamma 著者 Veras, H, Figueira, A.C, le Maire, A. 登録日 2017-08-11 公開日 2018-02-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.687 Å) 主引用文献 Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties. Front Endocrinol (Lausanne), 9, 2018
1NI0	Structure of the Y94F mutant of the restriction endonuclease PvuII 分子名称: Type II restriction enzyme PvuII 著者 Tucker, P.A, Kokkinidis, M, Nicolaki, S, Kotsifaki, D. 登録日 2002-12-20 公開日 2003-02-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Y94F mutant of the restriction endonuclease PvuII To be Published
3SAG	Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site 分子名称: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION 著者 Januszyk, K, Liu, Q, Lima, C.D. 登録日 2011-06-02 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
3SAH	Crystal structure of the human RRP6 catalytic domain with Y436A mutation in the catalytic site 分子名称: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION 著者 Januszyk, K, Liu, Q, Lima, C.D. 登録日 2011-06-02 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
3HX1	Crystal structure of the Slr1951 protein from Synechocystis sp. Northeast Structural Genomics Consortium Target SgR167A 分子名称: Slr1951 protein 著者 Vorobiev, S, Chen, Y, Seetharaman, J, Janjua, J, Xiao, R, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2009-06-19 公開日 2009-06-30 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the Slr1951 protein from Synechocystis sp. To be Published
4OYQ	(6-isothiocyanatohexyl)benzene inhibitor complexed with Macrophage Migration Inhibitory Factor 分子名称: 6-isothiocyanatohexylbenzene, GLYCEROL, Macrophage migration inhibitory factor, ... 著者 Spencer, E.S, Dale, E.J, Gommans, A.L, Vo, C.T, Rutledge, M.T, Nakatani, Y, Gamble, A.B, Smith, R.A.J, Wilbanks, S.M, Hampton, M.B, Tyndall, J.D.A. 登録日 2014-02-12 公開日 2014-03-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 To be published To be published
4OSF	4-(2-isothiocyanatoethyl)phenol inhibitor complexed with Macrophage Migration Inhibitory Factor 分子名称: CHLORIDE ION, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Spencer, E.S, Dale, E.J, Gommans, A.L, Vo, C.T, Rutledge, M.T, Nakatani, Y, Gamble, A.B, Smith, R.A.J, Wilbanks, S.M, Hampton, M.B, Tyndall, J.D.A. 登録日 2014-02-12 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor Eur.J.Med.Chem., 93, 2015
3SOH	Architecture of the Flagellar Rotor 分子名称: Flagellar motor switch protein FliG, Flagellar motor switch protein FliM 著者 Koushik, P, Gonzalez-Bonet, G, Bilwes, A.M, Crane, B.R, Blair, D. 登録日 2011-06-30 公開日 2011-07-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Architecture of the flagellar rotor. Embo J., 30, 2011
7XN2	Crystal structure of CvkR, a novel MerR-type transcriptional regulator 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Alr3614 protein, DI(HYDROXYETHYL)ETHER 著者 Liang, Y.J, Zhu, T, Ma, H.L, Lu, X.F, Hess, W.R. 登録日 2022-04-27 公開日 2023-03-08 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 CvkR is a MerR-type transcriptional repressor of class 2 type V-K CRISPR-associated transposase systems. Nat Commun, 14, 2023
1LJT	Crystal Structure of Macrophage Migration Inhibitory Factor complexed with (S,R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole-acetic acid methyl ester (ISO-1) 分子名称: 3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER, Macrophage migration inhibitory factor 著者 Lubetsky, J.B, Dios, A, Han, J, Aljabari, B, Ruzsicska, B, Mitchell, R, Lolis, E, Al-Abed, Y. 登録日 2002-04-22 公開日 2002-11-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Tautomerase Active Site of Macrophage Migration Inhibitory factor is a Potential Target for Discovery of Novel Anti-inflammatory Agents J.Biol.Chem., 277, 2002
3SQ6	Crystal Structures of the Ligand Binding Domain of a Pentameric Alpha7 Nicotinic Receptor Chimera with its Agonist Epibatidine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIBATIDINE, ... 著者 Li, S.-X, Huang, S, Bren, N, Noridomi, K, Dellisanti, C, Sine, S, Chen, L. 登録日 2011-07-05 公開日 2011-09-28 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Ligand-binding domain of an alpha 7-nicotinic receptor chimera and its complex with agonist. Nat.Neurosci., 14, 2011
6AUG	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with SR16832 分子名称: 2-chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid 著者 Shang, J, Kojetin, D.J. 登録日 2017-08-31 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma. Elife, 7, 2018
3V2R	COMPcc in complex with fatty acids 分子名称: Cartilage Oligomerization matrix protein (coiled-coil domain), OLEIC ACID 著者 Stetefeld, J. 登録日 2011-12-12 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 COMPcc in complex with fatty acids To be Published
8B2X	Structure of the type I-G CRISPR effector 分子名称: Type I-G CRISPR Cascade large subunit CSX17 著者 Shangguan, Q, Graham, S, Sundaramoorthy, R, White, M.F. 登録日 2022-09-15 公開日 2022-11-09 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Structure and mechanism of the type I-G CRISPR effector. Nucleic Acids Res., 50, 2022
3V7E	Crystal structure of YbxF bound to the SAM-I riboswitch aptamer 分子名称: COBALT HEXAMMINE(III), MAGNESIUM ION, Ribosome-associated protein L7Ae-like, ... 著者 Baird, N.J, Zhang, J, Hamma, T, Ferre-D'Amare, A.R. 登録日 2011-12-21 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 YbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loops. Rna, 18, 2012
7X1Y	Structure of the phosphorylation-site double mutant S431A/T432A of the KaiC circadian clock protein 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock oscillator protein KaiC, MAGNESIUM ION 著者 Han, X, Zhang, D.L, Hong, L, Yu, D.Q, Wu, Z.L, Yang, T, Rust, M.J, Tu, Y.H, Ouyang, Q. 登録日 2022-02-25 公開日 2023-04-26 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Determining subunit-subunit interaction from statistics of cryo-EM images: observation of nearest-neighbor coupling in a circadian clock protein complex Nat Commun, 14, 2023
3FJC	Crystal structure of L44W mutant of Human acidic fibroblast growth factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Blaber, M, Lee, J. 登録日 2008-12-14 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1. J.Mol.Biol., 393, 2009
3FGM	Crystal structure of L44F/C83T/C117V/F132W mutant of Human acidic fibroblast growth factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Blaber, M, Lee, J. 登録日 2008-12-06 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1. J.Mol.Biol., 393, 2009

<1228122912301231123212331234123512361237123812391240124112421243>