PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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7AHX	HIV-1 REVERSE TRANSCRIPTASE COMPLEX WITH DNA AND D-ASPARTATE TENOFOVIR WITH BOUND MANGANESE 分子名称: D-Aspartate Tenofovir, DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)*CP*GP*CP*CP*(DDG))-3'), DNA (5'-D(*TP*GP*GP*TP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3'), ... 著者 Gu, W, Martinez, S.E, Nguyen, H, Xu, H, Herdewijn, P, de Jonghe, S, Das, K. 登録日 2020-09-25 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Tenofovir-Amino Acid Conjugates Act as Polymerase Substrates-Implications for Avoiding Cellular Phosphorylation in the Discovery of Nucleotide Analogues. J.Med.Chem., 64, 2021
7JXT	Ovine COX-1 in complex with the subtype-selective derivative 2a 分子名称: 2-[4,5-bis(2-chlorophenyl)-1H-imidazol-2-yl]-6-(prop-2-en-1-yl)phenyl methoxyacetate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Ko, Y, Iaselli, M, Miciaccia, M, Friedrich, L, Schneider, G, Scilimati, A, Cingolani, G. 登録日 2020-08-27 公開日 2021-09-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase-1 Inhibitors by Automated De Novo Design. Adv Sci, 8, 2021
7PY4	Cryo-EM structure of ATP8B1-CDC50A in E2P autoinhibited state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BERYLLIUM TRIFLUORIDE ION, CHOLESTEROL HEMISUCCINATE, ... 著者 Dieudonne, T, Abad-Herrera, S, Juknaviciute Laursen, M, Lejeune, M, Stock, C, Slimani, K, Jaxel, C, Lyons, J.A, Montigny, C, Gunther Pomorski, T, Nissen, P, Lenoir, G. 登録日 2021-10-08 公開日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders. Elife, 11, 2022
2M1S	NMR assignment of the arenaviral protein Z from Lassa fever virus 分子名称: RING finger protein Z, ZINC ION 著者 Volpon, L, Osborne, M.J, Borden, K.L.B. 登録日 2012-12-06 公開日 2013-01-30 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E Proc.Natl.Acad.Sci.USA, 107, 2010
2MDG	Solution NMR Structure of Zinc finger protein 423 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR7298F 分子名称: ZINC ION, Zinc finger protein 423 著者 Pederson, K, Lee, D, Kohan, E, Janjua, H, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG) 登録日 2013-09-10 公開日 2013-09-25 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of Zinc finger protein 423 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR7298F To be Published
7SJX	Cryo-EM Structure of the PR-RT components of the HIV-1 Pol Polyprotein 分子名称: Gag-Pol polyprotein 著者 Lyumkis, D, Passos, D, Arnold, E, Harrison, J.J.E.K, Ruiz, F.X. 登録日 2021-10-19 公開日 2022-07-27 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (8.2 Å) 主引用文献 Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation. Sci Adv, 8, 2022
2MFE	Csr/Rsm protein-RNA recognition - A molecular affinity ruler: RsmZ(SL2)/RsmE(dimer) 2:1 complex 分子名称: Carbon storage regulator homolog, SL2(RsmZ) RNA 著者 Duss, O, Diarra Dit Konte, N, Michel, E, Schubert, M, Allain, F.H.-T. 登録日 2013-10-11 公開日 2014-02-26 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition. Nucleic Acids Res., 42, 2014
7E4W	Human Transcriptional Co-activator PC4 (C-terminal Domain) in space group P1211 分子名称: Activated RNA polymerase II transcriptional coactivator p15 著者 Dev, A, Pandey, B, Basu, G. 登録日 2021-02-15 公開日 2021-09-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insights on the disruption of the complex between human positive coactivator 4 and p53 by small molecules. Biochem.Biophys.Res.Commun., 578, 2021
2ZUH	Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant (D297A) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... 著者 Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. 登録日 2008-10-18 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant to be published
2ZWF	Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 80 minutes 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2008-12-03 公開日 2009-12-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase To be Published
8OQZ	Structure of human gamma-secretase PSEN1 APH-1B isoform reconstituted into lipid nanodisc in complex with Ab46 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Odorcic, I, Chavez Gutierrez, L, Efremov, R.G. 登録日 2023-04-12 公開日 2024-04-24 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Apo and A beta 46-bound gamma-secretase structures provide insights into amyloid-beta processing by the APH-1B isoform. Nat Commun, 15, 2024
7Q19	Beta-lactoglobulin mutant FAW (I56F/L39A/M107W) in complex with desipramine (FAW-DSM#3) 分子名称: 1,2-ETHANEDIOL, 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, Beta-lactoglobulin, ... 著者 Loch, J.I, Barciszewski, J, Pokrywka, K, Lewinski, K. 登録日 2021-10-18 公開日 2022-05-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 New ligand-binding sites identified in the crystal structures of [beta]-lactoglobulin complexes with desipramine Iucrj, 9, 2022
2MI7	Solution NMR structure of alpha3Y 分子名称: de novo protein a3Y 著者 Glover, S.D, Jorge, C, Liang, L, Valentine, K.G, Hammarstrom, L, Tommos, C. 登録日 2013-12-10 公開日 2014-08-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Photochemical tyrosine oxidation in the structurally well-defined alpha 3Y protein: proton-coupled electron transfer and a long-lived tyrosine radical. J.Am.Chem.Soc., 136, 2014
7AO5	Crystal structure of CotB2 variant W288F 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclooctat-9-en-7-ol synthase, MAGNESIUM ION 著者 Dimos, N, Driller, R, Loll, B. 登録日 2020-10-13 公開日 2020-12-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol. J.Am.Chem.Soc., 142, 2020
7DU6	Crystal structure of the rationally designed mkDPBB_sym2 protein 分子名称: mkDPBB_sym2 protein 著者 Yagi, S, Tagami, S. 登録日 2021-01-08 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase. J.Am.Chem.Soc., 143, 2021
7DU7	Crystal structure of the rationally designed mkDPBB_sym1 protein 分子名称: mkDPBB_sym1 protein 著者 Yagi, S, Tagami, S. 登録日 2021-01-08 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.201 Å) 主引用文献 Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase. J.Am.Chem.Soc., 143, 2021
2J4O	Structure of TAB1 分子名称: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING PROTEIN 1 著者 van Aalten, D. 登録日 2006-09-01 公開日 2006-09-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Tak1-Binding Protein 1 is a Pseudophosphatase. Biochem.J., 399, 2006
2ZVW	Crystal structure of Proliferating cell nuclear antigen 2 and Short peptide from human P21 分子名称: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen 2, SULFATE ION 著者 Strzalka, W, Oyama, T, Tori, K, Morikawa, K. 登録日 2008-11-21 公開日 2009-06-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of the Arabidopsis thaliana proliferating cell nuclear antigen 1 and 2 proteins complexed with the human p21 C-terminal segment Protein Sci., 18, 2009
7SPM	Replication Initiator Protein REPE54 and cognate DNA sequence with terminal three prime phosphates chemically crosslinked (30 mg/mL EDC, 12 hours, 2 doses). 分子名称: DNA (5'-D(*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*A)-3'), MAGNESIUM ION, ... 著者 Ward, A.R, Snow, C.D. 登録日 2021-11-02 公開日 2021-11-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.28 Å) 主引用文献 Stabilizing DNA-Protein Co-Crystals via Intra-Crystal Chemical Ligation of the DNA Crystals, 12, 2022
7DXX	Crystal structure of the mk2h_deltaMILPS peptide homodimer 分子名称: MALONIC ACID, mk2h_deltaMILPS protein 著者 Yagi, S, Tagami, S. 登録日 2021-01-20 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.403 Å) 主引用文献 Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase. J.Am.Chem.Soc., 143, 2021
7JVH	Crystal structure of a GH43_12 retrieved from capybara gut metagenome 分子名称: GLYCEROL, Glycoside Hydrolase Family 43_12 著者 Cabral, L, Domingues, M.N, Martins, M.P, Persinoti, G.F, Morais, M.A.B, Murakami, M.T. 登録日 2020-08-21 公開日 2021-09-08 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Crystal structure of a GH43_12 retrieved from capybara gut metagenome To Be Published
7PGX	Structure of dark-adapted AsLOV2 wild type 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Gelfert, R, Weyand, M, Moeglich, A. 登録日 2021-08-16 公開日 2022-05-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.001 Å) 主引用文献 Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine. Nat Commun, 13, 2022
7DXZ	Crystal structure of the chemically synthesized mk2h_deltaMILPYS peptide homodimer in complex with malonate 分子名称: MALONIC ACID, mk2h_deltaMILPYS protein 著者 Yagi, S, Tagami, S. 登録日 2021-01-20 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase. J.Am.Chem.Soc., 143, 2021
2MGY	Solution structure of the mitochondrial translocator protein (TSPO) in complex with its high-affinity ligand PK11195 分子名称: N-[(2R)-butan-2-yl]-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, Translocator protein 著者 Jaremko, M, Jaremko, L, Giller, K, Becker, S, Zweckstetter, M. 登録日 2013-11-11 公開日 2014-04-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science, 343, 2014
7DVH	Crystal structure of the computationally designed reDPBB_sym4 protein 分子名称: reDPBB_sym4 protein 著者 Yagi, S, Tagami, S, Padhi, A.K, Zhang, K.Y.J. 登録日 2021-01-13 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase. J.Am.Chem.Soc., 143, 2021

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