8J2F
| Human neutral shpingomyelinase | 分子名称: | HEPTANE, MAGNESIUM ION, Sphingomyelin phosphodiesterase 2, ... | 著者 | Zhang, S.S. | 登録日 | 2023-04-14 | 公開日 | 2023-12-06 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2). Nat Commun, 14, 2023
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2YBH
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2YBM
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2BPU
| The Kedge Holmium Derivative of Hen Egg-White Lysozyme at high resolution from Single Wavelength Anomalous Diffraction | 分子名称: | CHLORIDE ION, HOLMIUM ATOM, LYSOZYME C, ... | 著者 | Jakoncic, J, Di Michiel, M, Zhong, Z, Honkimaki, V, Jouanneau, Y, Stojanoff, V. | 登録日 | 2005-04-25 | 公開日 | 2006-08-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Anomalous Diffraction at Ultra-High Energy for Protein Crystallography. J.Appl.Crystallogr., 39, 2006
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2YC5
| Inhibitors of the herbicidal target IspD | 分子名称: | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC, 5-chloro-7-hydroxy-6-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile, ... | 著者 | Hoeffken, H.W. | 登録日 | 2011-03-11 | 公開日 | 2011-08-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Inhibitors of the Herbicidal Target Ispd: Allosteric Site Binding. Angew.Chem.Int.Ed.Engl., 50, 2011
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2BWI
| Atomic Resolution Structure of Nitrite -soaked Achromobacter cycloclastes Cu Nitrite Reductase | 分子名称: | ACETATE ION, COPPER (II) ION, COPPER-CONTAINING NITRITE REDUCTASE, ... | 著者 | Antonyuk, S.V, Strange, R.W, Sawers, G, Eady, R.R, Hasnain, S.S. | 登録日 | 2005-07-14 | 公開日 | 2005-08-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic Resolution Structures of Resting-State, Substrate- and Product-Complexed Cu-Nitrite Reductase Provide Insight Into Catalytic Mechanism Proc.Natl.Acad.Sci.USA, 102, 2005
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2YBJ
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8JEL
| Crystal structure of TIGIT in complexed with Ociperlimab, crystal form I | 分子名称: | T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain | 著者 | Sun, J, Zhang, X.X, Song, J. | 登録日 | 2023-05-16 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 32, 2024
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2YBU
| Crystal structure of human acidic chitinase in complex with bisdionin F | 分子名称: | 3,7-DIMETHYL-1-[3-(3-METHYL-2,6-DIOXO-9H-PURIN-1-YL)PROPYL]PURINE-2,6-DIONE, ACIDIC MAMMALIAN CHITINASE, GLYCEROL | 著者 | Sutherland, T.E, Andersen, O.A, Betou, M, Eggleston, I.M, Maizels, R.M, van Aalten, D, Allen, J.E. | 登録日 | 2011-03-10 | 公開日 | 2011-06-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Analyzing airway inflammation with chemical biology: dissection of acidic mammalian chitinase function with a selective drug-like inhibitor. Chem. Biol., 18, 2011
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8JEQ
| Crystal structure of Tiragolumab | 分子名称: | antibody heavy chain, antibody light chain | 著者 | Sun, J, Zhang, X.X, Song, J. | 登録日 | 2023-05-16 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 32, 2024
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7O1B
| Human phosphomannomutase 2 (PMM2) wild-type co-crystallized with the activator glucose 1,6-bisphosphate | 分子名称: | 1,6-di-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. | 登録日 | 2021-03-29 | 公開日 | 2022-02-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
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7O5Z
| Human phosphomannomutase 2 (PMM2) with mutation T237M in apo state | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. | 登録日 | 2021-04-09 | 公開日 | 2022-02-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
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8JEO
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7O58
| Human phosphomannomutase 2 (PMM2) with mutation T237M in complex with the activator glucose 1,6-bisphosphate | 分子名称: | 1,6-di-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | 著者 | Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. | 登録日 | 2021-04-08 | 公開日 | 2022-02-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
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8J40
| Crystal Structure of CATB8 in complex with chloramphenicol | 分子名称: | CHLORAMPHENICOL, CatB8, GLYCEROL, ... | 著者 | Liao, J, Kuang, L, Jiang, Y. | 登録日 | 2023-04-18 | 公開日 | 2024-02-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Chloramphenicol Binding Sites of Acinetobacter baumannii Chloramphenicol Acetyltransferase CatB8. Acs Infect Dis., 10, 2024
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8JEN
| Crystal structure of TIGIT in complexed with Ociperlimab, crystal form II | 分子名称: | T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain | 著者 | Sun, J, Zhang, X.X, Song, J. | 登録日 | 2023-05-16 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 32, 2024
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8JEP
| Crystal structure of Ociperlimab | 分子名称: | antibody heavy chain, antibody light chain | 著者 | Sun, J, Zhang, X.X, Song, J. | 登録日 | 2023-05-16 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 32, 2024
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2YDG
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8IYX
| Cryo-EM structure of the GPR34 receptor in complex with the antagonist YL-365 | 分子名称: | 1-[4-(3-chlorophenyl)phenyl]carbonyl-4-[2-(4-phenylmethoxyphenyl)ethanoylamino]piperidine-4-carboxylic acid, Probable G-protein coupled receptor 34,YL-365 | 著者 | Jia, G.W, Wang, X, Zhang, C.B, Dong, H.H, Su, Z.M. | 登録日 | 2023-04-06 | 公開日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | 主引用文献 | Cryo-EM structures of human GPR34 enable the identification of selective antagonists. Proc.Natl.Acad.Sci.USA, 120, 2023
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2YAZ
| The Crystal Structure of Leishmania major dUTPase in complex dUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, DUTPASE, MAGNESIUM ION, ... | 著者 | Hemsworth, G.R, Moroz, O.V, Fogg, M.J, Scott, B, Bosch-Navarrete, C, Gonzalez-Pacanowska, D, Wilson, K.S. | 登録日 | 2011-02-25 | 公開日 | 2011-03-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine. J.Biol.Chem., 286, 2011
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2YAY
| The Crystal Structure of Leishmania major dUTPase in complex with substrate analogue dUpNpp | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, DUTPASE | 著者 | Hemsworth, G.R, Moroz, O.V, Fogg, M.J, Scott, B, Bosch-Navarrete, C, Gonzalez-Pacanowska, D, Wilson, K.S. | 登録日 | 2011-02-25 | 公開日 | 2011-03-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine. J.Biol.Chem., 286, 2011
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2YBN
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2YCM
| Inhibitors of herbicidal target IspD | 分子名称: | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC, 6-BENZYL-5-CHLORO-7-HYDROXYPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID, ... | 著者 | Hoeffken, H.W. | 登録日 | 2011-03-16 | 公開日 | 2011-08-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Inhibitors of the Herbicidal Target Ispd: Allosteric Site Binding. Angew.Chem.Int.Ed.Engl., 50, 2011
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1C9H
| CRYSTAL STRUCTURE OF FKBP12.6 IN COMPLEX WITH RAPAMYCIN | 分子名称: | FKBP12.6, RAPAMYCIN IMMUNOSUPPRESSANT DRUG | 著者 | Deivanayagam, C.C.S, Carson, M, Thotakura, A, Narayana, S.V.L, Chodavarapu, C.S. | 登録日 | 1999-08-02 | 公開日 | 2000-08-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of FKBP12.6 in complex with rapamycin. Acta Crystallogr.,Sect.D, 56, 2000
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2YBL
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