2YC5

Inhibitors of the herbicidal target IspD

Summary for 2YC5

Entry DOI	10.2210/pdb2yc5/pdb
Related	1W77 2YC3 2YCM
Descriptor	2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC, 5-chloro-7-hydroxy-6-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile, COPPER (II) ION, ... (9 entities in total)
Functional Keywords	transferase, non-mevalonate-pathway, herbicide, allosteric pocket
Biological source	ARABIDOPSIS THALIANA (THALE CRESS)
Cellular location	Plastid, chloroplast (Probable): P69834
Total number of polymer chains	1
Total formula weight	26473.56
Authors	Hoeffken, H.W. (deposition date: 2011-03-11, release date: 2011-08-24, Last modification date: 2023-12-20)
Primary citation	Witschel, M.C.,Hoeffken, H.W.,Seet, M.,Parra, L.,Mietzner, T.,Thater, F.,Niggeweg, R.,Rohl, F.,Illarionov, B.,Rohdich, F.,Kaiser, J.,Fischer, M.,Bacher, A.,Diederich, F. Inhibitors of the Herbicidal Target Ispd: Allosteric Site Binding. Angew.Chem.Int.Ed.Engl., 50:7931-, 2011 Cited by PubMed: 21766403 DOI: 10.1002/ANIE.201102281 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation