1G97
 
 | | S.PNEUMONIAE GLMU COMPLEXED WITH UDP-N-ACETYLGLUCOSAMINE AND MG2+ | | 分子名称: | MAGNESIUM ION, N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE, SODIUM ION, ... | | 著者 | Kostrewa, D, D'Arcy, A, Kamber, M. | | 登録日 | 2000-11-22 | | 公開日 | 2001-05-22 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Crystal structures of Streptococcus pneumoniae N-acetylglucosamine-1-phosphate uridyltransferase, GlmU, in apo form at 2.33 A resolution and in complex with UDP-N-acetylglucosamine and Mg(2+) at 1.96 A resolution.
J.Mol.Biol., 305, 2001
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4JY7
 | | Crystal structure of Acinetobacter baumannii Peptidyl-tRNA Hydrolase | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Yamini, S, Kaushik, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2013-03-29 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Mode of Inhibitor Binding to Peptidyl-tRNA Hydrolase: Binding Studies and Structure Determination of Unbound and Bound Peptidyl-tRNA Hydrolase from Acinetobacter baumannii
Plos One, 8, 2013
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3HFP
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2BML
 | | Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AUTOLYSIN, DEXTROFLOXACINE, ... | | 著者 | Fernandez-Tornero, C, Gimenez-Gallego, G, Romero, A, Garcia, E, Pascual-Teresa, B.D, Lopez, R. | | 登録日 | 2005-03-15 | | 公開日 | 2005-03-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Ofloxacin-Like Antibiotics Inhibit Pneumococcal Cell Wall-Degrading Virulence Factors
J.Biol.Chem., 280, 2005
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3ZIA
 | | The structure of F1-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF1 | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Robinson, G.C, Bason, J.V, Montgomery, M.G, Fearnley, I.M, Mueller, D.M, Leslie, A.G.W, Walker, J.E. | | 登録日 | 2013-01-07 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Structure of F1-ATPase from Saccharomyces Cerevisiae Inhibited by its Regulatory Protein If1.
Open Biol., 3, 2013
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7CM3
 | | Cryo-EM structure of human NALCN in complex with FAM155A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wu, J, Yan, Z, Ke, M. | | 登録日 | 2020-07-24 | | 公開日 | 2020-11-11 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the human sodium leak channel NALCN in complex with FAM155A.
Nat Commun, 11, 2020
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6M66
 | | The Cryo-EM Structure of Human Pannexin 1 | | 分子名称: | Pannexin-1 | | 著者 | Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S. | | 登録日 | 2020-03-13 | | 公開日 | 2020-04-15 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Cryo-EM structures of human pannexin 1 channel.
Cell Res., 30, 2020
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1ROP
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1W6B
 | | Solution NMR Structure of a Long Neurotoxin from the Venom of the Asian Cobra, 20 Structures | | 分子名称: | LONG NEUROTOXIN 1 | | 著者 | Talebzadeh-Farooji, M, Amininasab, M, Elmi, M.M, Naderi-Manesh, H, Sarbolouki, M.N. | | 登録日 | 2004-08-17 | | 公開日 | 2004-12-22 | | 最終更新日 | 2024-11-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy.
Eur. J. Biochem., 271, 2004
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4Y7B
 | | Factor Xa complex with GTC000441 | | 分子名称: | 6-chloro-N-{(3S)-1-[(2S)-1-{(1R,5S)-7-[2-(methylamino)ethyl]-3,7-diazabicyclo[3.3.1]non-3-yl}-1-oxopropan-2-yl]-2-oxopy rrolidin-3-yl}naphthalene-2-sulfonamide, CALCIUM ION, Coagulation factor X | | 著者 | Convery, M.A, Young, R.J, Senger, S, Hamblin, J.N, Chan, C, Toomey, J.R, Watson, N.S. | | 登録日 | 2015-02-13 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Factor Xa complex with GTC000441
to be published
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7E6H
 | | glucose-6-phosphate dehydrogenase from Kluyveromyces lactis | | 分子名称: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glucose-6-phosphate 1-dehydrogenase | | 著者 | Ha, V.H, Chang, J.H. | | 登録日 | 2021-02-22 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for substrate recognition of glucose-6-phosphate dehydrogenase from Kluyveromyces lactis.
Biochem.Biophys.Res.Commun., 553, 2021
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6FF4
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2018-08-29 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
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5OP3
 | | Designed Ankyrin Repeat Protein (DARPin) NDNH-1 selected by directed evolution against Lysozyme | | 分子名称: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Fischer, G, Hogan, B.J, Houlihan, G, Edmond, S, Huovinen, T.T.K, Hollfelder, F, Hyvonen, M. | | 登録日 | 2017-08-09 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.359 Å) | | 主引用文献 | Designed Ankyrin Repeat Protein (DARPin) NDNH-1 selected by directed evolution against Lysozyme
To be published
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3TK8
 | | Structure of a 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase from Burkholderia pseudomallei | | 分子名称: | 1,2-ETHANEDIOL, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, SULFATE ION, ... | | 著者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2011-08-25 | | 公開日 | 2011-10-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of a 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase from Burkholderia pseudomallei
TO BE PUBLISHED
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4YC9
 | | Crystal structure of TRIM24 PHD-bromodomain complexed with N-(6-{3-[4-(dimethylamino)butoxy]-5-propoxyphenoxy}-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-3,4-dimethoxybenzene-1-sulfonamide (8i) | | 分子名称: | GLYCEROL, N-(6-{3-[4-(dimethylamino)butoxy]-5-propoxyphenoxy}-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-3,4-dimethoxybenzenesulfonamide, Transcription intermediary factor 1-alpha, ... | | 著者 | Poncet-Montange, G, Palmer, W, Jones, P. | | 登録日 | 2015-02-19 | | 公開日 | 2015-06-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
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4BDG
 | | Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) | | 分子名称: | 1,2-ETHANEDIOL, 3-(PYRIDIN-3-YL)-1H-PYRAZOL-5-AMINE, CHLORIDE ION, ... | | 著者 | Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M. | | 登録日 | 2012-10-05 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2.
Plos One, 8, 2013
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9F1C
 | | Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Yudin, D, Scaiola, A, Ban, N. | | 登録日 | 2024-04-18 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | NAC guides a ribosomal multienzyme complex for nascent protein processing.
Nature, 633, 2024
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5ECN
 | | Crystal Structure of FIN219-FIP1 complex with JA, Leu and ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE, Glutathione S-transferase U20, ... | | 著者 | Chen, C.Y, Cheng, Y.S. | | 登録日 | 2015-10-20 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1W91
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7E9J
 | | Crystal Structure of POMGNT2 in complex with UDP | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, ... | | 著者 | Kuwabara, N. | | 登録日 | 2021-03-04 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structure of POMGNT2 provides new insights into the mechanism to determine the functional O-mannosylation site on alpha-dystroglycan.
Genes Cells, 26, 2021
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4L8O
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4IFP
 | | X-ray Crystal Structure of Human NLRP1 CARD Domain | | 分子名称: | MALONATE ION, Maltose-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 1, ... | | 著者 | Jin, T, Curry, J, Smith, P, Jiang, J, Xiao, T. | | 登録日 | 2012-12-14 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9948 Å) | | 主引用文献 | Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1.
Proteins, 81, 2013
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2Y5W
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9FFO
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4ILX
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