9FFO

Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived asymmetric bound-closed 2 state of branch 1

This is a non-PDB format compatible entry.

Summary for 9FFO

• Entry DOI: 10.2210/pdb9ffo/pdb
• EMDB information: 50368
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit beta-3, Megabody25,Outer membrane protein, ... (8 entities in total)
• Functional Keywords: gaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 294427.86

Authors

Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-05-23, release date: 2025-06-04, Last modification date: 2025-08-06)

• Primary citation: Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.; Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived asymmetric pre-active 2 state of branch 1; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.2 Å)