4J7Y
 
 | | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | | 分子名称: | D-gamma-glutamyl-(Z)-N-(carboxymethylidene)-S-[(2R)-2-hydroxy-4-phenylbutyl]-L-cysteinamide, Leukotriene C4 synthase, NICKEL (II) ION, ... | | 著者 | Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. | | 登録日 | 2013-02-14 | | 公開日 | 2014-01-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | | 主引用文献 | Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
|
|
4J7T
 | | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | | 分子名称: | D-gamma-glutamyl-S-(4-phenylbutyl)-L-cysteinylglycine, Leukotriene C4 synthase, NICKEL (II) ION, ... | | 著者 | Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. | | 登録日 | 2013-02-14 | | 公開日 | 2014-01-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.203 Å) | | 主引用文献 | Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
|
|
1N8I
 | | Biochemical and Structural Studies of Malate Synthase from Mycobacterium tuberculosis | | 分子名称: | GLYOXYLIC ACID, MAGNESIUM ION, Probable malate synthase G | | 著者 | Smith, C.V, Huang, C.C, Miczak, A, Russell, D.G, Sacchettini, J.C, Honer zu Bentrup, K, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2002-11-20 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis
J.Biol.Chem., 278, 2003
|
|
1D6I
 | | CHALCONE SYNTHASE (H303Q MUTANT) | | 分子名称: | CHALCONE SYNTHASE, SULFATE ION | | 著者 | Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. | | 登録日 | 1999-10-13 | | 公開日 | 2000-02-03 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry, 39, 2000
|
|
1D6H
 | | CHALONE SYNTHASE (N336A MUTANT COMPLEXED WITH COA) | | 分子名称: | CHALCONE SYNTHASE, COENZYME A, SULFATE ION | | 著者 | Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. | | 登録日 | 1999-10-13 | | 公開日 | 2000-02-03 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry, 39, 2000
|
|
2K0X
 | |
2K0Y
 | |
1D6F
 | | CHALCONE SYNTHASE C164A MUTANT | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHALCONE SYNTHASE, SULFATE ION | | 著者 | Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. | | 登録日 | 1999-10-13 | | 公開日 | 2000-02-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry, 39, 2000
|
|
3EUT
 | |
2FR0
 | |
2FR1
 | |
2VCW
 | | Complex structure of prostaglandin D2 synthase at 1.95A. | | 分子名称: | 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID, GLUTATHIONE, GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE | | 著者 | Hohwy, M, Spadola, L, Lundquist, B, von Wachenfeldt, K, Persdotter, S, Hawtin, P, Dahmen, J, Groth-Clausen, I, Folmer, R.H.A, Edman, K. | | 登録日 | 2007-09-27 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design.
J.Med.Chem., 51, 2008
|
|
2VD1
 | | Complex structure of prostaglandin D2 synthase at 2.25A. | | 分子名称: | 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid, GLUTATHIONE, GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, ... | | 著者 | Hohwy, M, Spadola, L, Lundquist, B, von Wachenfeldt, K, Persdotter, S, Hawtin, P, Dahmen, J, Groth-Clausen, I, Folmer, R.H.A, Edman, K. | | 登録日 | 2007-09-28 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design.
J.Med.Chem., 51, 2008
|
|
2VD0
 | | Complex structure of prostaglandin D2 synthase at 2.2A. | | 分子名称: | 2-{[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino}benzoic acid, GLUTATHIONE, GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, ... | | 著者 | Hohwy, M, Spadola, L, Lundquist, B, von Wachenfeldt, K, Persdotter, S, Hawtin, P, Dahmen, J, Groth-Clausen, I, Folmer, R.H.A, Edman, K. | | 登録日 | 2007-09-28 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design.
J.Med.Chem., 51, 2008
|
|
1F7T
 | | HOLO-(ACYL CARRIER PROTEIN) SYNTHASE AT 1.8A | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, GLYCEROL, ... | | 著者 | Parris, K.D, Lin, L, Tam, A, Mathew, R, Hixon, J, Stahl, M, Fritz, C.C, Seehra, J, Somers, W.S. | | 登録日 | 2000-06-27 | | 公開日 | 2001-06-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites.
Structure Fold.Des., 8, 2000
|
|
1F7L
 | | HOLO-(ACYL CARRIER PROTEIN) SYNTHASE IN COMPLEX WITH COENZYME A AT 1.5A | | 分子名称: | CALCIUM ION, CHLORIDE ION, COENZYME A, ... | | 著者 | Parris, K.D, Lin, L, Tam, A, Mathew, R, Hixon, J, Stahl, M, Fritz, C.C, Seehra, J, Somers, W.S. | | 登録日 | 2000-06-27 | | 公開日 | 2001-06-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites.
Structure Fold.Des., 8, 2000
|
|
1DV5
 | | TERTIARY STRUCTURE OF APO-D-ALANYL CARRIER PROTEIN | | 分子名称: | APO-D-ALANYL CARRIER PROTEIN | | 著者 | Volkman, B.F, Zhang, Q, Debabov, D.V, Rivera, E, Kresheck, G.C, Neuhaus, F.C. | | 登録日 | 2000-01-19 | | 公開日 | 2001-08-01 | | 最終更新日 | 2024-04-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Biosynthesis of D-alanyl-lipoteichoic acid: the tertiary structure of apo-D-alanyl carrier protein.
Biochemistry, 40, 2001
|
|
3GSS
 | | HUMAN GLUTATHIONE S-TRANSFERASE P1-1 IN COMPLEX WITH ETHACRYNIC ACID-GLUTATHIONE CONJUGATE | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ETHACRYNIC ACID, GLUTATHIONE, ... | | 著者 | Oakley, A.J, Rossjohn, J, Parker, M.W. | | 登録日 | 1996-10-29 | | 公開日 | 1997-11-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate.
Biochemistry, 36, 1997
|
|
2GSS
 | | HUMAN GLUTATHIONE S-TRANSFERASE P1-1 IN COMPLEX WITH ETHACRYNIC ACID | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ETHACRYNIC ACID, GLUTATHIONE S-TRANSFERASE P1-1, ... | | 著者 | Oakley, A.J, Rossjohn, J, Parker, M.W. | | 登録日 | 1996-10-29 | | 公開日 | 1997-11-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate.
Biochemistry, 36, 1997
|
|
7ZMD
 | |
7ZMA
 | |
2VB9
 | | beta-ketoacyl-ACP synthase I (KAS) from E. coli, apo structure | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, CHLORIDE ION | | 著者 | Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. | | 登録日 | 2007-09-06 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
2VBA
 | | beta-ketoacyl-ACP synthase I (KAS) from E. coli with bound amino- thiazole inhibitor | | 分子名称: | 2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE, 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1 | | 著者 | Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. | | 登録日 | 2007-09-06 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
2VB8
 | | beta-ketoacyl-ACP synthase I (KAS) from E. coli with bound inhibitor thiolactomycin | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, CHLORIDE ION, THIOLACTOMYCIN | | 著者 | Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. | | 登録日 | 2007-09-06 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
2VB7
 | | beta-ketoacyl-ACP synthase I (KAS) from E. coli, apo structure after soak in PEG solution | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1 | | 著者 | Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. | | 登録日 | 2007-09-06 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
