PDB: 5425 件ウェブページステータス検索Chemie searchBIRD

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3US5	Crystal structure of a RNA-binding domain of a poly-U binding splicing factor 60KDa (PUF60) from Homo sapiens at 1.38 A resolution 分子名称: CHLORIDE ION, Poly(U)-binding-splicing factor PUF60 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-11-23 公開日 2012-01-11 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Crystal structure of a RNA-binding domain of a poly-U binding splicing factor 60KDa (PUF60) from Homo sapiens at 1.38 A resolution To be published
4A0L	Structure of DDB1-DDB2-CUL4B-RBX1 bound to a 12 bp abasic site containing DNA-duplex 分子名称: 12 BP DNA DUPLEX, 12 BP THF CONTAINING DNA DUPLEX, CULLIN-4B, ... 著者 Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H. 登録日 2011-09-09 公開日 2011-12-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (7.4 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
4A08	Structure of hsDDB1-drDDB2 bound to a 13 bp CPD-duplex (purine at D-1 position) at 3.0 A resolution (CPD 1) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*AP*CP*GP*CP*GP*AP*(TTD)P*GP*CP*GP*CP*CP*C)-3', 5'-D(*TP*GP*GP*GP*CP*GP*CP*CP*CP*TP*CP*GP*CP*G)-3', ... 著者 Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H. 登録日 2011-09-08 公開日 2011-11-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation Cell(Cambridge,Mass.), 147, 2011
4A90	Crystal structure of mouse SAP18 residues 1-143 分子名称: GLYCEROL, HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 著者 Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E. 登録日 2011-11-22 公開日 2012-03-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex Nat.Struct.Mol.Biol., 19, 2012
4A0A	Structure of hsDDB1-drDDB2 bound to a 16 bp CPD-duplex (pyrimidine at D-1 position) at 3.6 A resolution (CPD 3) 分子名称: 5'-D(*CP*CP*TP*GP*CP*TP*CP*CP*TP*TP*TP*CP*AP*CP*CP*C)-3', 5'-D(*GP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*DGP)-3', CALCIUM ION, ... 著者 Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H. 登録日 2011-09-08 公開日 2011-11-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation Cell(Cambridge,Mass.), 147, 2011
2AKM	Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Gamma enolase, MAGNESIUM ION, ... 著者 Qin, J, Chai, G, Brewer, J.M, Lovelace, L.L. 登録日 2005-08-03 公開日 2006-03-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Fluoride inhibition of enolase: crystal structure and thermodynamics Biochemistry, 45, 2006
4A4D	Crystal structure of the N-terminal domain of the Human DEAD-BOX RNA helicase DDX5 (P68) 分子名称: PROBABLE ATP-DEPENDENT RNA HELICASE DDX5 著者 Dutta, S, Choi, Y.W, Kotaka, M, Fielding, B.C, Tan, Y.J. 登録日 2011-10-11 公開日 2012-08-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Variable N-Terminal Region of Ddx5 Contains Structural Elements and Auto-Inhibits its Interaction with Ns5B of Hepatitis C Virus. Biochem.J., 446, 2012
2F1O	Crystal Structure of NQO1 with Dicoumarol 分子名称: BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE], FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1 著者 Shaul, Y, Asher, G, Dym, O, Tsvetkov, P, Adler, J, Israel Structural Proteomics Center (ISPC) 登録日 2005-11-15 公開日 2006-05-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol. Biochemistry, 45, 2006
4A09	Structure of hsDDB1-drDDB2 bound to a 15 bp CPD-duplex (purine at D-1 position) at 3.1 A resolution (CPD 2) 分子名称: 5'-D(*CP*CP*TP*GP*CP*TP*CP*CP*TP*TP*TP*CP*AP*CP*CP*C)-3', 5'-D(*GP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*GP)-3', CALCIUM ION, ... 著者 Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H. 登録日 2011-09-08 公開日 2011-11-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation Cell(Cambridge,Mass.), 147, 2011
2FBX	WRN exonuclease, Mg complex 分子名称: MAGNESIUM ION, Werner syndrome helicase 著者 Perry, J.J. 登録日 2005-12-10 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat.Struct.Mol.Biol., 13, 2006
2CPJ	Solution structure of the N-terminal RNA recognition motif of NonO 分子名称: Non-POU domain-containing octamer-binding protein 著者 Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-19 公開日 2005-11-19 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the N-terminal RNA recognition motif of NonO To be Published
2CPR	Solution structure of the HRDC domain of human Exosome component 10 分子名称: Exosome component 10 著者 Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-19 公開日 2005-11-19 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the HRDC domain of human Exosome component 10 To be Published
2CPL	SIMILARITIES AND DIFFERENCES BETWEEN HUMAN CYCLOPHILIN A AND OTHER BETA-BARREL STRUCTURES. STRUCTURAL REFINEMENT AT 1.63 ANGSTROMS RESOLUTION 分子名称: CYCLOPHILIN A 著者 Ke, H. 登録日 1992-06-30 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Similarities and differences between human cyclophilin A and other beta-barrel structures. Structural refinement at 1.63 A resolution. J.Mol.Biol., 228, 1992
4AJP	Human LDHA in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol- 6yl)amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid 分子名称: GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, SULFATE ION, ... 著者 Tucker, J.A, Brassington, C, Caputo, A, Ward, R, Pearson, S, Watson, M, Tart, J, Davies, G. 登録日 2012-02-16 公開日 2012-03-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
2FC0	WRN exonuclease, Mn dGMP complex 分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Werner syndrome helicase 著者 Perry, J.J, Tainer, J.A. 登録日 2005-12-10 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat.Struct.Mol.Biol., 13, 2006
2FBY	WRN exonuclease, Eu complex 分子名称: EUROPIUM (III) ION, Werner syndrome helicase 著者 Perry, J.J. 登録日 2005-12-10 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat.Struct.Mol.Biol., 13, 2006
2DME	Solution structure of the TFIIS domain II of human PHD finger protein 3 分子名称: PHD finger protein 3 著者 Yoneyama, M, Tochio, N, Koshiba, S, Watabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-21 公開日 2006-10-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the TFIIS domain II of human PHD finger protein 3 To be Published
2DSC	Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADP-sugar pyrophosphatase, MAGNESIUM ION 著者 Zha, M, Zhong, C, Ding, J. 登録日 2006-06-28 公開日 2006-11-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity J.Mol.Biol., 364, 2006
4A9L	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 1,3-DIMETHYL-6-(MORPHOLINE- 4-SULFONYL)-1,2,3,4-TETRAHYDROQUINAZOLIN-2-ONE 分子名称: 1,2-ETHANEDIOL, 1,3-dimethyl-6-(morpholin-4-ylsulfonyl)-3,4-dihydroquinazolin-2(1H)-one, BROMODOMAIN-CONTAINING PROTEIN 4, ... 著者 Chung, C.W, Bamborough, P. 登録日 2011-11-26 公開日 2012-01-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Fragment-Based Discovery of Bromodomain Inhibitors Part 1: Inhibitor Binding Modes and Implications for Lead Discovery. J.Med.Chem., 55, 2012
4AJ2	rat LDHA in complex with 5-(2-chlorophenyl)-1H-tetrazole 分子名称: 5-(2-CHLOROPHENYL)-1H-TETRAZOLE, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, ... 著者 Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G, Frazer, M. 登録日 2012-02-15 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
4AJE	rat LDHA in complex with 2-(4-bromophenoxy)propanedioic acid 分子名称: 2-(4-BROMANYLPHENOXY)PROPANEDIOIC ACID, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, ... 著者 Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G, Pearson, S. 登録日 2012-02-16 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
4AJO	rat LDHA in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol-6yl) amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, ... 著者 Tucker, J.A, Brassington, C, Hassall, G, Watson, M, Ward, R, Tart, J, Davies, G, Caputo, A, Pearson, S. 登録日 2012-02-16 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
2DSD	Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and AMP 分子名称: ADENOSINE MONOPHOSPHATE, ADP-sugar pyrophosphatase, MAGNESIUM ION 著者 Zha, M, Zhong, C, Ding, J. 登録日 2006-06-28 公開日 2006-11-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity J.Mol.Biol., 364, 2006
4AJL	rat LDHA in complex with 3-(ethylcarbamoylamino)-N-(2-methyl-1,3- benzothiazol-6-yl)propanamide 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, ... 著者 Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G, Addie, M, Ferguson, A. 登録日 2012-02-16 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
2DWB	Aurora-A kinase complexed with AMPPNP 分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, Serine/threonine-protein kinase 6 著者 Kukimoto-Niino, M, Murayama, K, Shirouzu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-08-10 公開日 2007-07-31 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Aurora-A kinase complexed with AMPPNP To be Published

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