Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2F1O

Crystal Structure of NQO1 with Dicoumarol

Summary for 2F1O
Entry DOI10.2210/pdb2f1o/pdb
DescriptorNAD(P)H dehydrogenase [quinone] 1, BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE], FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywordsprotein inhibitor, structural genomics, israel structural proteomics center, ispc, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P15559
Total number of polymer chains8
Total formula weight255186.06
Authors
Shaul, Y.,Asher, G.,Dym, O.,Tsvetkov, P.,Adler, J.,Israel Structural Proteomics Center (ISPC) (deposition date: 2005-11-15, release date: 2006-05-16, Last modification date: 2023-08-23)
Primary citationAsher, G.,Dym, O.,Tsvetkov, P.,Adler, J.,Shaul, Y.
The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol.
Biochemistry, 45:6372-6378, 2006
Cited by
PubMed: 16700548
DOI: 10.1021/bi0600087
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.75 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon