2F1O
Crystal Structure of NQO1 with Dicoumarol
Summary for 2F1O
Entry DOI | 10.2210/pdb2f1o/pdb |
Descriptor | NAD(P)H dehydrogenase [quinone] 1, BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE], FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | protein inhibitor, structural genomics, israel structural proteomics center, ispc, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P15559 |
Total number of polymer chains | 8 |
Total formula weight | 255186.06 |
Authors | Shaul, Y.,Asher, G.,Dym, O.,Tsvetkov, P.,Adler, J.,Israel Structural Proteomics Center (ISPC) (deposition date: 2005-11-15, release date: 2006-05-16, Last modification date: 2023-08-23) |
Primary citation | Asher, G.,Dym, O.,Tsvetkov, P.,Adler, J.,Shaul, Y. The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol. Biochemistry, 45:6372-6378, 2006 Cited by PubMed: 16700548DOI: 10.1021/bi0600087 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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