PDB: 3581 件ウェブページステータス検索Chemie searchBIRD

---

6F0B	Cytochrome P450 TxtC employs substrate conformational switching for sequential aliphatic and aromatic thaxtomin hydroxylation 分子名称: (3~{S},6~{S})-1,4-dimethyl-3-[(4-nitro-1~{H}-indol-3-yl)methyl]-6-(phenylmethyl)piperazine-2,5-dione, Cytochrome P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE 著者 Fulop, V. 登録日 2017-11-17 公開日 2018-12-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC. J.Am.Chem.Soc., 141, 2019
6F8C	Crystal structure of cytochrome P450 CYP260A1 (S276I) bound with progesterone 分子名称: Cytochrome P450 CYP260A1, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2017-12-12 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone. ACS Chem. Biol., 13, 2018
2BVJ	Ligand-free structure of cytochrome P450 PikC (CYP107L1) 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BETA-MERCAPTOETHANOL, CYTOCHROME P450 MONOOXYGENASE, ... 著者 Sherman, D.H, Li, S, Yermalitskaya, L.V, Kim, Y, Smith, J.A, Waterman, M.R, Podust, L.M. 登録日 2005-06-28 公開日 2006-07-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae. J.Biol.Chem., 281, 2006
6F85	Crystal structure of cytochrome P450 CYP260A1 (S276N) bound with histidine 分子名称: Cytochrome P450 CYP260A1, HISTIDINE, PROTOPORPHYRIN IX CONTAINING FE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2017-12-12 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone. ACS Chem. Biol., 13, 2018
6F8A	Crystal structure of cytochrome P450 CYP260A1 (S276I) bound with histidine 分子名称: Cytochrome P450 CYP260A1, HISTIDINE, PROTOPORPHYRIN IX CONTAINING FE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2017-12-12 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone. ACS Chem. Biol., 13, 2018
6G5Q	The structure of a carbohydrate active P450 分子名称: 6-O-methyl-beta-D-galactopyranose, Cytochrome P450, GLYCEROL, ... 著者 Robb, C.S, Hehemann, J.H. 登録日 2018-03-29 公開日 2018-11-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases. Biochem. J., 475, 2018
6FSH	Crystal structure of hybrid P450 OxyBtei(BC/FGvan) 分子名称: ACETATE ION, OxyB protein, POTASSIUM ION, ... 著者 Brieke, C, Tarnawski, M, Greule, A, Cryle, M.J. 登録日 2018-02-19 公開日 2018-05-23 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach. J. Inorg. Biochem., 185, 2018
2CP4	CRYSTAL STRUCTURE OF THE CYTOCHROME P450-CAM ACTIVE SITE MUTANT THR252ALA 分子名称: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE 著者 Raag, R, Poulos, T.L. 登録日 1991-06-04 公開日 1993-01-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala. Biochemistry, 30, 1991
6EIG	Crystal structure of N24Q/C128T mutant of Channelrhodopsin 2 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Archaeal-type opsin 2, EICOSANE, ... 著者 Kovalev, K, Borshchevskiy, V, Volkov, O, Polovinkin, V, Marin, E, Balandin, T, Astashkin, R, Bamann, C, Bueldt, G, Willlbold, D, Popov, A, Bamberg, E, Gordeliy, V. 登録日 2017-09-19 公開日 2017-12-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insights into ion conduction by channelrhodopsin 2. Science, 358, 2017
6FSA	Beta-Cardiac myosin post-rigor 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FORMIC ACID, ... 著者 Robert-Paganin, J, Auguin, D, Houdusse, A. 登録日 2018-02-19 公開日 2018-07-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition. Nat Commun, 9, 2018
6FYJ	Cytochrome P450 peroxygenase CYP152K6 in complex with Myristic Acid 分子名称: DI(HYDROXYETHYL)ETHER, Fatty-acid peroxygenase, MYRISTIC ACID, ... 著者 Girvan, H.M, Poddar, H, Mclean, K.J, Leys, D, Munro, A.W. 登録日 2018-03-12 公開日 2018-08-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus. J. Inorg. Biochem., 188, 2018
6G5O	The structure of a carbohydrate active P450 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Robb, C.S, Hehemann, J.H. 登録日 2018-03-29 公開日 2018-11-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases. Biochem. J., 475, 2018
6GK5	Crystal structure of cytochrome P450 CYP267B1 from Sorangium cellulosum So ce56 分子名称: Cytochrome P450 CYP267B1 protein, PROTOPORPHYRIN IX CONTAINING FE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2018-05-18 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural insights into oxidation of medium-chain fatty acids and flavanone by myxobacterial cytochrome P450 CYP267B1. Biochem. J., 475, 2018
6G71	Structure of CYP1232A24 from Arthrobacter sp. 分子名称: 1,2-ETHANEDIOL, Cytochrome P450, FE (III) ION, ... 著者 Dubiel, P, Sharma, M, Klenk, J, Hauer, B, Grogan, G. 登録日 2018-04-04 公開日 2019-03-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine. J.Biochem., 166, 2019
6GEO	Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121A1 in complex with Triazole Pyrazole inhibitor 10j 分子名称: 2-chloranyl-3-[4-(imidazol-1-ylmethyl)-1-phenyl-pyrazol-3-yl]-1~{H}-indole, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C.W. 登録日 2018-04-27 公開日 2019-08-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Design and Synthesis of Imidazole and Triazole Pyrazoles asMycobacterium TuberculosisCYP121A1 Inhibitors. Chemistryopen, 8, 2019
6GEQ	Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121A1 in complex with Triazole Pyrazole inhibitor 14a 分子名称: 1-phenyl-3-pyridin-4-yl-~{N}-(pyridin-4-ylmethyl)pyrazole-4-carboxamide, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C.W. 登録日 2018-04-27 公開日 2019-08-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Design and Synthesis of Imidazole and Triazole Pyrazoles asMycobacterium TuberculosisCYP121A1 Inhibitors. Chemistryopen, 8, 2019
6FVC	Protein environment affects the water-tryptophan binding mode. Molecular dynamics simulations of Engrailed homeodomain mutants 分子名称: Segmentation polarity homeobox protein engrailed 著者 Trosanova, Z, Zachrdla, M, Jansen, S, Srb, P, Zidek, L, Kozelka, J. 登録日 2018-03-02 公開日 2019-04-03 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Protein environment affects the water-tryptophan binding mode. MD, QM/MM, and NMR studies of engrailed homeodomain mutants. Phys Chem Chem Phys, 20, 2018
2CPP	HIGH-RESOLUTION CRYSTAL STRUCTURE OF CYTOCHROME P450-CAM 分子名称: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE 著者 Poulos, T.L. 登録日 1987-04-06 公開日 1987-07-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 High-resolution crystal structure of cytochrome P450cam. J.Mol.Biol., 195, 1987
2FER	P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX 分子名称: Cytochrome P450-cam, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING MN 著者 von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I. 登録日 2005-12-16 公開日 2006-03-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The status of high-valent metal oxo complexes in the P450 cytochromes. J.Inorg.Biochem., 100, 2006
2FEU	P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... 著者 von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I. 登録日 2005-12-16 公開日 2006-03-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The status of high-valent metal oxo complexes in the P450 cytochromes. J.Inorg.Biochem., 100, 2006
2FE6	P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX 分子名称: Cytochrome P450-cam, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING MN 著者 von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I. 登録日 2005-12-15 公開日 2006-03-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The status of high-valent metal oxo complexes in the P450 cytochromes. J.Inorg.Biochem., 100, 2006
2FR7	Crystal Structure of Cytochrome P450 CYP199A2 分子名称: PROTOPORPHYRIN IX CONTAINING FE, putative cytochrome P450 著者 Rao, Z, Wong, L.L, Xu, F, Bell, S.G. 登録日 2006-01-19 公開日 2007-01-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structure of CYP199A2, a para-substituted benzoic acid oxidizing cytochrome P450 from Rhodopseudomonas palustris J.Mol.Biol., 383, 2008
4CQI	Crystal structure of recombinant tubulin-binding cofactor A (TBCA) from Leishmania major 分子名称: GLYCEROL, SULFATE ION, TUBULIN-BINDING COFACTOR A 著者 Barrack, K.L, Fyfe, P.K, Hunter, W.N. 登録日 2014-02-17 公開日 2014-11-26 最終更新日 2015-05-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Structure of Tubulin-Binding Cofactor a from Leishmania Major Infers a Mode of Association During the Early Stages of Microtubule Assembly Acta Crystallogr.,Sect.F, 71, 2015
4CP4	CRYSTAL STRUCTURE OF THE CYTOCHROME P450-CAM ACTIVE SITE MUTANT THR252ALA 分子名称: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE 著者 Raag, R, Poulos, T.L. 登録日 1991-06-04 公開日 1993-01-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala. Biochemistry, 30, 1991
7JW5	Crystal structure of WT-CYP199A4 in complex with 4-phenylbenzoic acid 分子名称: CHLORIDE ION, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Lee, J.H.Z, Bruning, J.B, Bell, S.G. 登録日 2020-08-24 公開日 2021-09-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.526 Å) 主引用文献 Different Geometric Requirements for Cytochrome P450-Catalyzed Aliphatic Versus Aromatic Hydroxylation Results in Chemoselective Oxidation Acs Catalysis, 12, 2022

<111112113114115116117118119120121122123124125126>