PDB: 5425 件ウェブページステータス検索Chemie searchBIRD

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3ZYL	Structure of a truncated CALM (PICALM) ANTH domain 分子名称: PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN 著者 Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J. 登録日 2011-08-23 公開日 2011-12-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell, 147, 2011
3ZEH	Solution structure of the Hs. PSIP1 PWWP domain 分子名称: PC4 AND SFRS1-INTERACTING PROTEIN 著者 van Ingen, H, van Nuland, R, Timmers, H.T.M, Boelens, R. 登録日 2012-12-05 公開日 2013-05-22 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Nucleosomal DNA Binding Drives the Recognition of H3K36-Methylated Nucleosomes by the Psip1-Pwwp Domain. Epigenetics Chromatin, 6, 2013
3ZMV	LSD1-CoREST in complex with PLSFLV peptide 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PKSFLV PEPTIDE, ... 著者 Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A. 登録日 2013-02-12 公開日 2013-06-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase. Acs Chem.Biol., 8, 2013
2EJE	Solution Structure of RSGI RUH-071, a GTF2I domain in human cDNA 分子名称: General transcription factor II-I 著者 Doi-Katayama, Y, Hirota, H, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-16 公開日 2007-09-18 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution Structure of RSGI RUH-071, a GTF2I domain in human cDNA To be Published
2EC1	Solution structure of the RanBD1 domain from human Nucleoporin 50 kDa 分子名称: Nucleoporin 50 kDa 著者 Zhang, H.P, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-09 公開日 2007-08-14 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the RanBD1 domain from human Nucleoporin 50 kDa To be published
4AJN	rat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)-3-oxo-propyl)carbamoylamino)ethyl)phenyl)methyl) propanedioic acid 分子名称: (4-{2-[({3-[(2-METHYL-1,3-BENZOTHIAZOL-6-YL)AMINO]-3-OXOPROPYL}CARBAMOYL)AMINO]ETHYL}BENZYL)PROPANEDIOIC ACID, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN 著者 Tucker, J.A, Brassington, C, Hassall, G, Watson, M, Ward, R, Tart, J, Davies, G, Caputo, A, Pearson, S. 登録日 2012-02-16 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
2EJ4	Functional and structural basis of nuclear localization signal in ZIC3 zinc finger domain: a role of conserved tryptophan residue in the zinc finger domain 分子名称: ZINC ION, Zinc finger protein ZIC 3 著者 Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-14 公開日 2008-02-05 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Functional and structural basis of nuclear localization signal in ZIC3 zinc finger domain: a role of conserved tryptophan residue in the zinc finger domain To be Published
2EJR	LSD1-tranylcypromine complex 分子名称: Lysine-specific histone demethylase 1, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-5-[7,8-DIMETHYL-2,4-DIOXO-5-(3-PHENYLPROPANOYL)-1,3,4,5-TETRAHYDROBENZO[G]PTERIDIN-10(2H)-YL]-2,3,4-TRIHYDROXYPENTYL DIHYDROGEN DIPHOSPHATE 著者 Sengoku, T, Mimasu, S, Umehara, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-20 公開日 2008-01-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25A Biochem.Biophys.Res.Commun., 366, 2008
4A4O	CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 2-(2-AMINO- PYRIMIDIN-4-YL)-1,5,6,7-TETRAHYDRO-PYRROLOPYRIDIN-4-ONE INHIBITOR 分子名称: 1-METHYL-2-(2-{[5-(4-METHYLPIPERAZIN-1-YL)-2-(TRIFLUOROMETHOXY)PHENYL]AMINO}PYRIMIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, L(+)-TARTARIC ACID, SERINE/THREONINE-PROTEIN KINASE PLK1, ... 著者 Bertrand, J.A, Bossi, R.T. 登録日 2011-10-18 公開日 2012-01-11 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 5-(2-Amino-Pyrimidin-4-Yl)-1H-Pyrrole and 2-(2-Amino-Pyrimidin-4-Yl)-1,5,6,7-Tetrahydro-Pyrrolo[3,2-C]Pyridin-4-One Derivatives as New Classes of Selective and Orally Available Polo-Like Kinase 1 Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
4AJ1	rat LDHA in complex with N-(2-(methylamino)-1,3-benzothiazol-6-yl) acetamide 分子名称: GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, MALONATE ION, ... 著者 Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G. 登録日 2012-02-15 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
2B8A	High Resolution Structure of the HDGF PWWP Domain 分子名称: Hepatoma-derived growth factor 著者 Lukasik, S.M, Cierpicki, T, Borloz, M, Grembecka, J, Everett, A, Bushweller, J.H. 登録日 2005-10-06 公開日 2005-12-06 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 High resolution structure of the HDGF PWWP domain: a potential DNA binding domain. Protein Sci., 15, 2006
3W8I	Crystal structure of CCM3 in complex with the C-terminal regulatory domain of MST4 分子名称: Programmed cell death protein 10, Serine/threonine-protein kinase MST4 著者 Xu, X, Wang, D.C, Ding, J. 登録日 2013-03-13 公開日 2013-07-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III. Structure, 21, 2013
2ALD	HUMAN MUSCLE ALDOLASE 分子名称: FRUCTOSE-BISPHOSPHATE ALDOLASE 著者 Dalby, A.R, Littlechild, J.A. 登録日 1998-10-21 公開日 1999-04-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications. Protein Sci., 8, 1999
4A11	Structure of the hsDDB1-hsCSA complex 分子名称: DNA DAMAGE-BINDING PROTEIN 1, DNA EXCISION REPAIR PROTEIN ERCC-8 著者 Bohm, K, Scrima, A, Fischer, E.S, Gut, H, Thomae, N.H. 登録日 2011-09-13 公開日 2011-12-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
4A0W	model built against symmetry-free cryo-EM map of TRiC-ADP-AlFx 分子名称: T-COMPLEX PROTEIN 1 SUBUNIT BETA 著者 Cong, Y, Schroder, G.F, Meyer, A.S, Jakana, J, Ma, B, Dougherty, M.T, Schmid, M.F, Reissmann, S, Levitt, M, Ludtke, S.L, Frydman, J, Chiu, W. 登録日 2011-09-13 公開日 2012-02-15 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (13.9 Å) 主引用文献 Symmetry-Free Cryo-Em Structures of the Chaperonin Tric Along its ATPase-Driven Conformational Cycle. Embo J., 31, 2012
4AJJ	rat LDHA in complex with 2-((3,4-dimethoxyphenyl)methyl))propanedioic acid and N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido-propanamide 分子名称: 2-((3,4-DIMETHOXYPHENYL)METHYL))PROPANEDIOIC ACID, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G, Patel, J, Greenwood, R. 登録日 2012-02-16 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
2B5L	Crystal Structure of DDB1 In Complex with Simian Virus 5 V Protein 分子名称: Nonstructural protein V, ZINC ION, damage-specific DNA binding protein 1 著者 Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N. 登録日 2005-09-28 公開日 2006-02-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell(Cambridge,Mass.), 124, 2006
4A13	model refined against symmetry-free cryo-EM map of TRiC-ADP 分子名称: T-COMPLEX PROTEIN 1 SUBUNIT BETA 著者 Cong, Y, Schroder, G.F, Meyer, A.S, Jakana, J, Ma, B, Dougherty, M.T, Schmid, M.F, Reissmann, S, Levitt, M, Ludtke, S.L, Frydman, J, Chiu, W. 登録日 2011-09-13 公開日 2012-02-15 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (11.3 Å) 主引用文献 Symmetry-Free Cryo-Em Structures of the Chaperonin Tric Along its ATPase-Driven Conformational Cycle. Embo J., 31, 2012
3UVL	Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL3 分子名称: Histone-lysine N-methyltransferase MLL3, WD repeat-containing protein 5 著者 Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F. 登録日 2011-11-30 公開日 2011-12-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases. Nucleic Acids Res., 40, 2012
3UO4	Aurora A in complex with RPM1680 分子名称: 1,2-ETHANEDIOL, 4-{[4-(biphenyl-2-ylamino)pyrimidin-2-yl]amino}benzoic acid, Aurora kinase A 著者 Martin, M.P, Zhu, J.-Y, Schonbrunn, E. 登録日 2011-11-16 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A. Acs Chem.Biol., 7, 2012
3UP7	Aurora A in complex with YL1-038-09 分子名称: 2-({2-[(4-carboxyphenyl)amino]pyrimidin-4-yl}amino)benzoic acid, Aurora kinase A 著者 Martin, M.P, Zhu, J.-Y, Schonbrunn, E. 登録日 2011-11-17 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Development of o-Chlorophenyl Substituted Pyrimidines as Exceptionally Potent Aurora Kinase Inhibitors. J.Med.Chem., 55, 2012
3UVK	Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL2 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase MLL2, SULFATE ION, ... 著者 Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F. 登録日 2011-11-30 公開日 2011-12-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases. Nucleic Acids Res., 40, 2012
4A6Q	Crystal structure of mouse SAP18 residues 6-143 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18, ISOPROPYL ALCOHOL 著者 Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E. 登録日 2011-11-08 公開日 2012-03-07 最終更新日 2015-03-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex Nat.Struct.Mol.Biol., 19, 2012
4ALD	HUMAN MUSCLE FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE COMPLEXED WITH FRUCTOSE 1,6-BISPHOSPHATE 分子名称: 1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM), FRUCTOSE-BISPHOSPHATE ALDOLASE 著者 Dalby, A.R, Dauter, Z, Littlechild, J.A. 登録日 1998-07-26 公開日 1999-03-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications. Protein Sci., 8, 1999
3ZKF	Structure of LC8 in complex with Nek9 phosphopeptide 分子名称: DYNEIN LIGHT CHAIN 1, CYTOPLASMIC, NEK9 PROTEIN 著者 Gallego, P, Velazquez-Campoy, A, Regue, L, Roig, J, Reverter, D. 登録日 2013-01-22 公開日 2013-03-20 最終更新日 2013-05-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Analysis of the Regulation of the Dynll/Lc8 Binding to Nek9 by Phosphorylation J.Biol.Chem., 288, 2013

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