3ZMV

LSD1-CoREST in complex with PLSFLV peptide

Summary for 3ZMV

Related3ZMS 3ZMT 3ZMU 3ZMZ 3ZN0 3ZN1
DescriptorLYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, PKSFLV PEPTIDE, ... (4 entities in total)
Functional Keywordstranscription, transcription factor, chromatin
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus O60341 Q9UKL0
Total number of polymer chains4
Total molecular weight150057.36
Authors
Tortorici, M.,Borrello, M.T.,Tardugno, M.,Chiarelli, L.R.,Pilotto, S.,Ciossani, G.,Vellore, N.A.,Cowan, J.,O'Connell, M.,Mai, A.,Baron, R.,Ganesan, A.,Mattevi, A. (deposition date: 2013-02-12, release date: 2013-06-12, Last modification date: 2013-08-28)
Primary citation
Tortorici, M.,Borrello, M.T.,Tardugno, M.,Chiarelli, L.R.,Pilotto, S.,Ciossani, G.,Vellore, N.A.,Bailey, S.G.,Cowan, J.,O'Connell, M.,Crabb, S.J.,Packham, G.K.,Mai, A.,Baron, R.,Ganesan, A.,Mattevi, A.
Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8:1677-, 2013
PubMed: 23721412 (PDB entries with the same primary citation)
DOI: 10.1021/CB4001926
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25750.4%3.5%1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report