3ZMS

LSD1-CoREST in complex with INSM1 peptide

Summary for 3ZMS

• Entry DOI: 10.2210/pdb3zms/pdb
• Related: 3ZMT 3ZMU 3ZMV 3ZMZ 3ZN0 3ZN1
• Descriptor: LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, INSULINOMA-ASSOCIATED PROTEIN 1, ... (4 entities in total)
• Functional Keywords: oxidoreductase-peptide complex, demethylase, transcription factor, chromatin, oxidoreductase/peptide
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: O60341 Q9UKL0; Nucleus (Potential): Q01101
• Total number of polymer chains: 3
• Total formula weight: 201607.90

Authors

Tortorici, M.,Borrello, M.T.,Tardugno, M.,Chiarelli, L.R.,Pilotto, S.,Ciossani, G.,Vellore, N.A.,Cowan, J.,O'Connell, M.,Mai, A.,Baron, R.,Ganesan, A.,Mattevi, A. (deposition date: 2013-02-12, release date: 2013-06-12, Last modification date: 2023-12-20)

• Primary citation: Tortorici, M.,Borrello, M.T.,Tardugno, M.,Chiarelli, L.R.,Pilotto, S.,Ciossani, G.,Vellore, N.A.,Bailey, S.G.,Cowan, J.,O'Connell, M.,Crabb, S.J.,Packham, G.K.,Mai, A.,Baron, R.,Ganesan, A.,Mattevi, A.; Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.; Acs Chem.Biol., 8:1677-, 2013; PubMed: 23721412; DOI: 10.1021/CB4001926

Experimental method

X-RAY DIFFRACTION (2.96 Å)