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6A28
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Crystal structure of PprA W183R mutant form 2
分子名称: DNA repair protein PprA, SULFATE ION
著者Adachi, M, Shibazaki, C, Shimizu, R, Arai, S, Satoh, K, Narumi, I, Kuroki, R.
登録日2018-06-09
公開日2018-12-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.193 Å)
主引用文献Extended structure of pleiotropic DNA repair-promoting protein PprA from Deinococcus radiodurans.
FASEB J., 33, 2019
3H9E
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Crystal structure of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDS) complex with NAD and phosphate
分子名称: 1,2-ETHANEDIOL, Glyceraldehyde-3-phosphate dehydrogenase, testis-specific, ...
著者Chaikuad, A, Shafqat, N, Yue, W, Cocking, R, Bray, J.E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2009-04-30
公開日2009-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS.
Biochem.J., 435, 2011
5ZU3
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Effect of mutation (R554K) on FAD modification in Aspergillus oryzae RIB40formate oxidase
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Formate oxidase, ...
著者Mikami, B, Uchida, H, Doubayashi, D.
登録日2018-05-06
公開日2019-05-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The microenvironment surrounding FAD mediates its conversion to 8-formyl-FAD in Aspergillus oryzae RIB40 formate oxidase.
J.Biochem., 166, 2019
6A2J
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Crystal structure of heme A synthase from Bacillus subtilis
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, COPPER (II) ION, Heme A synthase, ...
著者Niwa, S, Takeda, K, Kosugi, M, Tsutsumi, E, Miki, K.
登録日2018-06-12
公開日2018-11-21
最終更新日2018-12-12
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of heme A synthase fromBacillus subtilis.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4P7L
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Structure of Escherichia coli PgaB C-terminal domain, P212121 crystal form
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase
著者Little, D.J, Li, G, Ing, C, DiFrancesco, B, Bamford, N.C, Robinson, H, Nitz, M, Pomes, R, Howell, P.L.
登録日2014-03-27
公開日2014-07-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Modification and periplasmic translocation of the biofilm exopolysaccharide poly-beta-1,6-N-acetyl-D-glucosamine.
Proc.Natl.Acad.Sci.USA, 111, 2014
2ILU
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BU of 2ilu by Molmil
Crystal structure of lactaldehyde dehydrogenase from E. coli: the binary complex with NADPH
分子名称: Aldehyde dehydrogenase A, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
著者Di Costanzo, L, Gomez, G, Christianson, D.W.
登録日2006-10-03
公開日2007-05-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of lactaldehyde dehydrogenase from Escherichia coli and inferences regarding substrate and cofactor specificity.
J.Mol.Biol., 366, 2007
6I4T
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Crystal structure of the disease-causing I445M mutant of the human dihydrolipoamide dehydrogenase
分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Szabo, E, Wilk, P, Zambo, Z, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A.
登録日2018-11-10
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.823 Å)
主引用文献Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Hum.Mol.Genet., 28, 2019
2IPG
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Crystal structure of 17alpha-hydroxysteroid dehydrogenase mutant K31A in complex with NADP+ and epi-testosterone
分子名称: (10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE, 1,2-ETHANEDIOL, 3(17)alpha-hydroxysteroid dehydrogenase, ...
著者Faucher, F, Cantin, L, Pereira de Jesus-Tran, K, Lemieux, M, Luu-the, V, Labrie, F, Breton, R.
登録日2006-10-12
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mouse 17alpha-Hydroxysteroid Dehydrogenase (AKR1C21) Binds Steroids Differently from other Aldo-keto Reductases: Identification and Characterization of Amino Acid Residues Critical for Substrate Binding.
J.Mol.Biol., 369, 2007
3EJQ
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Golgi alpha-Mannosidase II in complex with 5-substitued swainsonine analog: (5R)-5-[2'-oxo-2'-(4-methylphenyl)ethyl]-swainsonine
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1-(4-methylphenyl)-2-[(1S,2R,5R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizin-5-yl]ethanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kuntz, D.A, Rose, D.R.
登録日2008-09-18
公開日2009-10-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural Investigation of the Binding of 5-Substituted Swainsonine Analogues to Golgi alpha-Mannosidase II.
Chembiochem, 11, 2010
5XGW
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Isoaspartyl dipeptidase from Colwellia psychrerythraea strain 34H
分子名称: Isoaspartyl dipeptidase, ZINC ION
著者Lee, J.H, Lee, C.W, Park, S.H.
登録日2017-04-18
公開日2018-06-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure and functional characterization of an isoaspartyl dipeptidase (CpsIadA) from Colwellia psychrerythraea strain 34H.
PLoS ONE, 12, 2017
6A4G
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Mandelate oxidase mutant-Y128F with the monooxide FMN adduct
分子名称: 1-deoxy-1-[(4aS)-4a-hydroxy-7,8-dimethyl-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-5-O-phosphono-D-ribitol, 4-hydroxymandelate oxidase
著者Li, T.L, Lin, K.H.
登録日2018-06-19
公開日2019-06-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural and chemical trapping of flavin-oxide intermediates reveals substrate-directed reaction multiplicity.
Protein Sci., 29, 2020
5XTJ
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Mannanase(RmMan134A)
分子名称: Endo beta-1,4-mannanase
著者Jiang, Z.Q, You, X, Huang, P.
登録日2017-06-19
公開日2018-06-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural and biochemical insights into the substrate-binding mechanism of a novel glycoside hydrolase family 134 beta-mannanase.
Biochim Biophys Acta Gen Subj, 1862, 2018
6A4N
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HEWL crystals soaked in 2.5M GuHCl for 8 minutes
分子名称: CHLORIDE ION, GLYCEROL, GUANIDINE, ...
著者Tushar, R, Kini, R.M, Koh, C.Y, Hosur, M.V.
登録日2018-06-20
公開日2019-03-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献X-ray crystallographic analysis of time-dependent binding of guanidine hydrochloride to HEWL: First steps during protein unfolding.
Int. J. Biol. Macromol., 122, 2019
2IUK
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BU of 2iuk by Molmil
Crystal structure of Soybean Lipoxygenase-D
分子名称: FE (III) ION, SEED LIPOXYGENASE
著者Youn, B, Sellhorn, G.E, Mirchel, R.J, Gaffney, B.J, Grimes, H.D, Kang, C.
登録日2006-06-05
公開日2006-10-11
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Vegetative Soybean Lipoxygenase Vlx-B and Vlx-D, and Comparisons with Seed Isoforms Lox-1 and Lox-3.
Proteins, 65, 2006
3EF9
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Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
分子名称: SULFATE ION, Thymidylate synthase
著者Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
登録日2008-09-08
公開日2010-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
7Q3X
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Crystal structure of Malate dehydrogenase from Haloarcula marismortui with Potassium and Chloride ions
分子名称: CHLORIDE ION, Malate dehydrogenase, POTASSIUM ION
著者Bertrand, Q, Roche, J, Girard, E, Madern, D.
登録日2021-10-29
公開日2022-02-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Resurrection of Ancestral Malate Dehydrogenases Reveals the Evolutionary History of Haloarchaeal Proteins.
To Be Published
6IK6
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Crystal structure of Tomato beta-galactosidase (TBG) 4 with beta-1,4-galactobiose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase, ...
著者Matsuyama, K, Nakae, S, Igarashi, K, Tada, T, Ishimaru, M.
登録日2018-10-15
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.791 Å)
主引用文献Substrate-recognition mechanism of tomato beta-galactosidase 4 using X-ray crystallography and docking simulation.
Planta, 252, 2020
4KUG
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Crystal structure of 3-hydroxybutylryl-CoA dehydrogenase with NAD from Clostridium butyricum
分子名称: 3-hydroxybutyryl-CoA dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kim, E.J, Kim, S, Kim, K.J.
登録日2013-05-22
公開日2014-05-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of (S)-3-hydroxybutylryl-CoA dehydrogenase form the n-butanol sysnthesizing bacterium, Clostridium butyricum
to be published
4PHU
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Crystal structure of Human GPR40 bound to allosteric agonist TAK-875
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DIMETHYL SULFOXIDE, Free fatty acid receptor 1,Lysozyme, ...
著者Srivastava, A, Yano, J.K, Hirozane, Y, Kefala, G, Snell, G, Lane, W, Gruswitz, F, Ivetac, A, Aertgeerts, K, Nguyen, J, Jennings, A, Okada, K.
登録日2014-05-07
公開日2014-07-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.332 Å)
主引用文献High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
Nature, 513, 2014
3HAZ
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Crystal structure of bifunctional proline utilization A (PutA) protein
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Tanner, J.J.
登録日2009-05-03
公開日2010-02-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum
Proc.Natl.Acad.Sci.USA, 107, 2010
4KVK
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Crystal structure of Oryza sativa fatty acid alpha-dioxygenase
分子名称: CALCIUM ION, CHLORIDE ION, DECYL-BETA-D-MALTOPYRANOSIDE, ...
著者Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G.
登録日2013-05-22
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structures of alpha-dioxygenase from Oryza sativa: Insights into substrate binding and activation by hydrogen peroxide.
Protein Sci., 22, 2013
4PJ2
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Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme
分子名称: GLYCEROL, Lysozyme, MAGNESIUM ION, ...
著者Leysen, S, Van Herreweghe, J.M, Yoneda, K, Ogata, M, Usui, T, Michiels, C.W, Araki, T, Strelkov, S.V.
登録日2014-05-10
公開日2015-02-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献The structure of the proteinaceous inhibitor PliI from Aeromonas hydrophila in complex with its target lysozyme.
Acta Crystallogr.,Sect.D, 71, 2015
2RAB
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Structure of glutathione amide reductase from Chromatium gracile in complex with NAD
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, NICKEL (II) ION, ...
著者Van Petegem, F, De Vos, D, Savvides, S, Vergauwen, B, Van Beeumen, J.
登録日2007-09-14
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Understanding nicotinamide dinucleotide cofactor and substrate specificity in class I flavoprotein disulfide oxidoreductases: crystallographic analysis of a glutathione amide reductase.
J.Mol.Biol., 374, 2007
5XJN
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cytochrome P450 CREJ in complex with (4-ethylphenyl) dihydrogen phosphate
分子名称: (4-ethylphenyl) dihydrogen phosphate, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
著者Dong, S, Du, L, Li, S, Feng, Y.
登録日2017-05-03
公開日2017-07-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Selective oxidation of aliphatic C-H bonds in alkylphenols by a chemomimetic biocatalytic system
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2RAY
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beta-chlorophenetole in complex with T4 lysozyme L99A
分子名称: (2-chloroethoxy)benzene, Lysozyme, PHOSPHATE ION
著者Graves, A.P, Boyce, S.E, Shoichet, B.K.
登録日2007-09-17
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Rescoring docking hit lists for model cavity sites: predictions and experimental testing.
J.Mol.Biol., 377, 2008

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