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2DQJ
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Crystal structure of hyhel-10 FV (wild-type) complexed with hen egg lysozyme at 1.8A resolution
分子名称: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
著者Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I.
登録日2006-05-26
公開日2007-01-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
6PLK
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BU of 6plk by Molmil
Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII
分子名称: Env, ZIKV-116 heavy chain, ZIKV-116 light chain
著者Zhao, H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-07-01
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
J.Exp.Med., 217, 2020
6IW5
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BU of 6iw5 by Molmil
Crystal structure of YFV-China sE in prefusion state
分子名称: Envelope protein
著者Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F.
登録日2018-12-04
公開日2019-02-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26, 2019
6PZW
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BU of 6pzw by Molmil
CryoEM derived model of NA-22 Fab in complex with N9 Shanghai2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NA-22 fragment antigen binding heavy chain, ...
著者Ward, A.B, Turner, H.L, Zhu, X.
登録日2019-08-01
公開日2019-12-04
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6PZD
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BU of 6pzd by Molmil
Crystal structure of the neuraminidase stabilization mutant Y169aH from A/Shanghai/2/2013 (H7N9)
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6PZE
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BU of 6pze by Molmil
Crystal structure of human NA-45 Fab in complex with neuraminidase Y169aH mutant from A/Shanghai/2/2013 (H7N9)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NA-45 FAB HEAVY CHAIN, ...
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6PZF
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BU of 6pzf by Molmil
Crystal structure of human NA-63 Fab in complex with neuraminidase from A/Hunan/02650/2016(H7N9)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6Z06
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BU of 6z06 by Molmil
Crystal structure of Puumala virus Gc in complex with Fab 4G2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, Fab 4G2 Heavy chain, ...
著者Rissanen, I.R, Stass, R, Krumm, S.A, Seow, J, Hulswit, R.J.G, Paesen, G.C, Hepojoki, J, Vapalahti, O, Lundkvist, A, Reynard, O, Volchkov, V, Doores, K.J, Huiskonen, J.T, Bowden, T.A.
登録日2020-05-07
公開日2020-12-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein.
Elife, 9, 2020
6W73
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BU of 6w73 by Molmil
Fab Structure of CD4 Binding Site (CD4bs) Huamn Monoclonal Antibody HmAb64
分子名称: CALCIUM ION, HmAb64 fab heavy chain, HmAb64 fab light chain
著者Kong, X, Pan, R.
登録日2020-03-18
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A CD4 Binding Site (CD4bs) Monoclonal Antibody Elicited from A Human Volunteer Immunized by a DNA Prime/Protein Boost gp120 HIV Vaccine
To Be Published
2IHL
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BU of 2ihl by Molmil
LYSOZYME (E.C.3.2.1.17) (JAPANESE QUAIL)
分子名称: JAPANESE QUAIL EGG WHITE LYSOZYME, SODIUM ION
著者Houdusse, A, Bentley, G.A, Poljak, R.J, Souchon, H, Zhang, Z.
登録日1993-06-29
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.
Proc.Natl.Acad.Sci.Usa, 90, 1993
5T78
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BU of 5t78 by Molmil
Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, Fab Fragment - AR20.5 - Heavy chain, Fab fragment AR20.5 - Light Chain, ...
著者Brooks, C.L, Movahedin, M.
登録日2016-09-02
公開日2017-01-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.
Glycobiology, 27, 2017
5T6P
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BU of 5t6p by Molmil
Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide
分子名称: Fab Fragment - Heavy Chain, Fab fragment AR20.5 - Light Chain, MUC1 Peptide Fragment
著者Brooks, C.L, Movahedin, M.
登録日2016-09-01
公開日2017-01-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.
Glycobiology, 27, 2017
7B09
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BU of 7b09 by Molmil
Puumala virus glycoprotein (Gc) in complex with fab fragment P-4G2.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ...
著者Rissanen, I, Stass, R, Huiskonen, J.T, Bowden, T.A.
登録日2020-11-19
公開日2020-12-16
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (13.4 Å)
主引用文献Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein.
Elife, 9, 2020
5NBW
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BU of 5nbw by Molmil
Crystal structure of the Fab fragment 22F12 in complex with 3-hydroxybenzo[a]pyrene
分子名称: Fab 22F12 (A,B), Fab 22F12 (L,H), benzo[a]pyren-3-ol
著者Skerra, A, Eichinger, A.
登録日2017-03-02
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Tight Molecular Recognition of Benzo[a]pyrene by a High-Affinity Antibody.
Angew. Chem. Int. Ed. Engl., 56, 2017
3A67
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BU of 3a67 by Molmil
Crystal Structure of HyHEL-10 Fv mutant LN31D complexed with hen egg white lysozyme
分子名称: IG VH, anti-lysozyme, Lysozyme C, ...
著者Yokota, A, Tsumoto, K, Shiroishi, M, Nakanishi, T, Kondo, H, Kumagai, I.
登録日2009-08-24
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex, HyHEL-10-hen egg white lysozyme
J.Biol.Chem., 285, 2010
3A6C
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BU of 3a6c by Molmil
Crystal Structure of HyHEL-10 Fv mutant LN92D complexed with hen egg white lysozyme
分子名称: IG VH, anti-lysozyme, Lysozyme C, ...
著者Yokota, A, Tsumoto, K, Shiroishi, M, Nakanishi, T, Kondo, H, Kumagai, I.
登録日2009-08-28
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex, HyHEL-10-hen egg white lysozyme
J.Biol.Chem., 285, 2010
5CZV
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BU of 5czv by Molmil
Crystal structure of Notch3 NRR in complex with 20350 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fab 20350 heavy chain, ...
著者Hu, T, Fryer, C, Chopra, R, Clark, K.
登録日2015-08-01
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Oncogene, 35, 2016
2XEJ
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BU of 2xej by Molmil
Human glutamate carboxypeptidase II in complex with ARM-M4, urea- based inhibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Zhang, A.X, Murelli, R, Barinka, C, Michel, J, Cocleaza, A, Jorgensen, W.L, Lubkowski, J, Spiegel, D.A.
登録日2010-05-14
公開日2010-09-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules.
J.Am.Chem.Soc., 132, 2010
1BVK
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BU of 1bvk by Molmil
HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME
分子名称: HULYS11, LYSOZYME
著者Holmes, M.A, Buss, T.N, Foote, J.
登録日1998-09-16
公開日1999-02-16
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Conformational correction mechanisms aiding antigen recognition by a humanized antibody.
J.Exp.Med., 187, 1998
5KOU
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BU of 5kou by Molmil
Crystal structure of the human astrovirus 2 capsid protein spike domain at 1.87-A resolution
分子名称: Capsid polyprotein VP25
著者Bogdanoff, W.A, DuBois, R.M.
登録日2016-07-01
公開日2016-11-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.867 Å)
主引用文献Structure of a Human Astrovirus Capsid-Antibody Complex and Mechanistic Insights into Virus Neutralization.
J. Virol., 91, 2017
6W05
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BU of 6w05 by Molmil
Crystal structure of Fab356 in complex with NPNA2 peptide from circumsporozoite protein
分子名称: Fab356 heavy chain, Fab356 light chain, NPNA2 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-02-29
公開日2020-07-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.516 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6W00
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BU of 6w00 by Molmil
Crystal structure of Fab239 in complex with NPNA2 peptide from circumsporozoite protein
分子名称: Fab239 heavy chain, Fab239 light chain, Immunoglobulin G-binding protein G, ...
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-02-28
公開日2020-07-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.853 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6WG1
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BU of 6wg1 by Molmil
Crystal structure of Fab399 in complex with NPNA6 peptide from circumsporozoite protein
分子名称: Fab399 heavy chain, Fab399 light chain, NPNA6 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.086 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6VLK
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BU of 6vlk by Molmil
A varicella-zoster virus glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B, ...
著者Xing, Y.
登録日2020-01-24
公開日2020-07-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4529 Å)
主引用文献A glycoprotein B-neutralizing antibody structure at 2.8 angstrom uncovers a critical domain for herpesvirus fusion initiation.
Nat Commun, 11, 2020
7B0A
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BU of 7b0a by Molmil
Puumala virus-like particle glycoprotein spike and lattice contacts model.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ...
著者Rissanen, I, Stass, R, Huiskonen, J.T, Bowden, T.A.
登録日2020-11-19
公開日2020-12-16
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (13.9 Å)
主引用文献Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein.
Elife, 9, 2020

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