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2HWV
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Crystal structure of an essential response regulator DNA binding domain, VicRc in Enterococcus faecalis, a member of the YycF subfamily.
分子名称: DNA-binding response regulator VicR, SULFATE ION
著者Trinh, C.H, Liu, Y, Phillips, S.E.V, Phillips-Jones, M.K.
登録日2006-08-02
公開日2007-01-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the response regulator VicR DNA-binding domain.
Acta Crystallogr.,Sect.D, 63, 2007
2MUG
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Protective cellular immunity against P. falciparum malaria merozoite is associated with a different P7 and P8 residue orientation in the MHC-peptide-TCR complex
分子名称: Serine-repeat antigen protein
著者Patarroyo, M, Salazar, L, Cifuentes, G, Lozano, J, Delgado, G, Rivera, Z, Rosas, J, Vargas, L.
登録日2014-09-09
公開日2014-10-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Protective cellular immunity against P. falciparum malaria merozoites is associated with a different P7 and P8 residue orientation in the MHC-peptide-TCR complex.
Biochimie, 88, 2006
3CBE
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Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments
分子名称: Green fluorescent protein, MAGNESIUM ION
著者Lohman, J.R.
登録日2008-02-21
公開日2008-08-19
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.488 Å)
主引用文献Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments
Biochemistry, 47, 2008
2HYP
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Crystal structure of Rv0805 D66A mutant
分子名称: BROMIDE ION, CACODYLATE ION, FE (III) ION, ...
著者Shenoy, A.R, Capuder, M, Draskovic, P, Lamba, D, Visweswariah, S.S, Podobnik, M.
登録日2006-08-07
公開日2006-12-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and Biochemical Analysis of the Rv0805 Cyclic Nucleotide Phosphodiesterase from Mycobacterium tuberculosis.
J.Mol.Biol., 365, 2007
2QPS
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"Sugar tongs" mutant Y380A in complex with acarbose
分子名称: Alpha-amylase type A isozyme, CALCIUM ION
著者Aghajari, N, Jensen, M.H, Tranier, S, Haser, R.
登録日2007-07-25
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity
Febs J., 274, 2007
2QQU
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Crystal structure of a cell-wall invertase (D239A) from Arabidopsis thaliana in complex with sucrose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-fructofuranosidase, ...
著者Lammens, W, Le Roy, K, Van Laere, A, Rabijns, A, Van den Ende, W.
登録日2007-07-27
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Crystal structures of Arabidopsis thaliana cell-wall invertase mutants in complex with sucrose.
J.Mol.Biol., 377, 2008
2I32
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Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly
分子名称: Anti-Silencing Factor 1 paralog a, Histone Regulatory homolog A
著者Marmorstein, R, Tang, Y.
登録日2006-08-17
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly.
Nat.Struct.Mol.Biol., 13, 2006
2QNO
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Crystal Structure of the Mutant E55Q of the Cellulase CEL48F in Complex with a Thio-Oligosaccharide
分子名称: 4-thio-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose, CALCIUM ION, Endoglucanase F
著者Parsiegla, G, Haser, R.
登録日2007-07-19
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of mutants of cellulase Cel48F of Clostridium cellulolyticum in complex with long hemithiocellooligosaccharides give rise to a new view of the substrate pathway during processive action
J.Mol.Biol., 375, 2008
2QQW
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Crystal structure of a cell-wall invertase (D23A) from Arabidopsis thaliana in complex with sucrose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-fructofuranosidase, ...
著者Lammens, W, Le Roy, K, Van Laere, A, Rabijns, A, Van den Ende, W.
登録日2007-07-27
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of Arabidopsis thaliana cell-wall invertase mutants in complex with sucrose.
J.Mol.Biol., 377, 2008
2QFZ
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Crystal structure of human TBC1 domain family member 22A
分子名称: TBC1 domain family member 22A, UNKNOWN ATOM OR ION
著者Tong, Y, Tempel, W, Dimov, S, Dong, A, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2007-06-28
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human TBC1 domain family member 22A.
To be Published
2HUR
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Escherichia coli nucleoside diphosphate kinase
分子名称: NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION
著者Moynie, L, Giraud, M.-F, Georgescauld, F, Lascu, I, Dautant, A.
登録日2006-07-27
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献The structure of the Escherichia coli nucleoside diphosphate kinase reveals a new quaternary architecture for this enzyme family
Proteins, 67, 2007
2QLW
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Crystal structure of rhamnose mutarotase RhaU of Rhizobium leguminosarum
分子名称: FORMIC ACID, MAGNESIUM ION, RhaU
著者Carpena, X, Loewen, P.C.
登録日2007-07-13
公開日2008-11-04
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献RhaU of Rhizobium leguminosarum is a rhamnose mutarotase.
J.Bacteriol., 190, 2008
2HV5
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Human Aldose Reductase complexed with inhibitor zopolrestat after three days soaking (3days_soaked_3)
分子名称: 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Steuber, H, Heine, A, Klebe, G.
登録日2006-07-27
公開日2006-10-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions.
J.Mol.Biol., 363, 2006
2QMK
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Human pancreatic alpha-amylase complexed with nitrite
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRITE ION, ...
著者Williams, L.K, Maurus, R, Brayer, G.D.
登録日2007-07-16
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
2QS8
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Crystal structure of a Xaa-Pro dipeptidase with bound methionine in the active site
分子名称: MAGNESIUM ION, METHIONINE, Xaa-Pro Dipeptidase
著者Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-07-30
公開日2007-08-21
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Functional annotation of two new carboxypeptidases from the amidohydrolase superfamily of enzymes.
Biochemistry, 48, 2009
2G0F
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Crystal Structure of P144A mutant of E.coli CcmG protein
分子名称: Thiol:disulfide interchange protein dsbE
著者Ouyang, N, Gao, Y.G, Hu, H.Y, Xia, Z.X.
登録日2006-02-12
公開日2006-12-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of E. coli CcmG and its mutants reveal key roles of the N-terminal beta-sheet and the fingerprint region
Proteins, 65, 2006
2G60
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BU of 2g60 by Molmil
Structure of anti-FLAG M2 Fab domain
分子名称: anti-FLAG M2 Fab heavy chain, anti-FLAG M2 Fab light chain
著者Roosild, T.P.
登録日2006-02-23
公開日2006-09-12
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins.
Acta Crystallogr.,Sect.F, 62, 2006
2QY6
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Crystal structure of the N-terminal domain of UPF0209 protein yfcK from Escherichia coli O157:H7
分子名称: UPF0209 protein yfcK
著者Bonanno, J.B, Dickey, M, Bain, K.T, Eberle, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-08-13
公開日2007-08-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the N-terminal domain of UPF0209 protein yfcK from Escherichia coli O157:H7.
To be Published
2R0X
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Crystal structure of a putative flavin reductase (ycdh, hs_1225) from haemophilus somnus 129pt at 1.06 A resolution
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Possible flavin reductase, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2007-08-21
公開日2007-09-04
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Crystal structure of putative flavin reductase (YP_719437.1) from Haemophilus somnus 129PT at 1.06 A resolution
To be published
2R1L
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OpdA from Agrobacterium radiobacter with bound diethyl thiophosphate from crystal soaking with the compound- 1.95 A
分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, FE (II) ION, ...
著者Ollis, D.L, Jackson, C.J, Foo, J.L, Kim, H.K, Carr, P.D, Liu, J.W, Salem, G.
登録日2007-08-23
公開日2008-02-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase
J.Mol.Biol., 375, 2008
2R3U
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Crystal structure of the PDZ deletion mutant of DegS
分子名称: Protease degS
著者Clausen, T, Kurzbauer, R.
登録日2007-08-30
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
2R4F
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Substituted Pyrazoles as Hepatselective HMG-COA reductase inhibitors
分子名称: (3R,5R)-7-[1-(4-fluorophenyl)-4-(1-methylethyl)-3-{methyl[(1R)-1-phenylethyl]carbamoyl}-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION
著者Pavlovsky, A, Pfefferkorn, J.A, Harris, M.S, Finzel, B.C.
登録日2007-08-31
公開日2008-04-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia.
J.Med.Chem., 51, 2008
2QHF
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Mycobacterium tuberculosis Chorismate synthase in complex with NCA
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CHLORIDE ION, ...
著者Bruning, M, Bourenkov, G.P, Strizhov, N.I, Bartunik, H.D.
登録日2007-07-02
公開日2008-07-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Mycobacterium tuberculosis Chorismate synthase in complex with NCA
To be Published
2QKW
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Structural basis for activation of plant immunity by bacterial effector protein AvrPto
分子名称: Avirulence protein, Protein kinase
著者Xing, W.M, Zou, Y, Liu, Q, Hao, Q, Zhou, J.M, Chai, J.J.
登録日2007-07-11
公開日2007-08-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The structural basis for activation of plant immunity by bacterial effector protein AvrPto
Nature, 449, 2007
2G9I
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Crystal structure of homolog of F420-0:gamma-Glutamyl Ligase from Archaeoglobus fulgidus Reveals a Novel Fold.
分子名称: F420-0:gamma-glutamyl ligase
著者Nocek, B, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-03-06
公開日2006-04-04
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of an amide bond forming F(420):gamma-glutamyl ligase from Archaeoglobus fulgidus -- a member of a new family of non-ribosomal peptide synthases.
J.Mol.Biol., 372, 2007

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