5UZ9
| Cryo EM structure of anti-CRISPRs, AcrF1 and AcrF2, bound to type I-F crRNA-guided CRISPR surveillance complex | 分子名称: | Anti-CRISPR protein 30, Anti-CRISPR protein Acr30-35, CRISPR RNA (60-MER), ... | 著者 | Chowdhury, S, Carter, J, Rollins, M.F, Jackson, R.N, Hoffmann, C, Nosaka, L, Bondy-Denomy, J, Maxwell, K.L, Davidson, A.R, Fischer, E.R, Lander, G.C, Wiedenheft, B. | 登録日 | 2017-02-25 | 公開日 | 2017-04-26 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex. Cell, 169, 2017
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6ZWO
| cryo-EM structure of human mTOR complex 2, focused on one half | 分子名称: | ACETYL GROUP, INOSITOL HEXAKISPHOSPHATE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Scaiola, A, Mangia, F, Imseng, S, Boehringer, D, Ban, N, Maier, T. | 登録日 | 2020-07-28 | 公開日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The 3.2- angstrom resolution structure of human mTORC2. Sci Adv, 6, 2020
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6ZWM
| cryo-EM structure of human mTOR complex 2, overall refinement | 分子名称: | ACETYL GROUP, INOSITOL HEXAKISPHOSPHATE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Scaiola, A, Mangia, F, Imseng, S, Boehringer, D, Ban, N, Maier, T. | 登録日 | 2020-07-28 | 公開日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The 3.2- angstrom resolution structure of human mTORC2. Sci Adv, 6, 2020
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8VRJ
| Rigid body fitted model for gamma tubulin ring complex capped microtubule | 分子名称: | Actin, cytoplasmic 1, Gamma-tubulin complex component 3, ... | 著者 | Aher, A, Urnavicius, L, Kapoor, T.M. | 登録日 | 2024-01-22 | 公開日 | 2024-03-27 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structure of the gamma-tubulin ring complex-capped microtubule. Nat.Struct.Mol.Biol., 31, 2024
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5HMB
| Crystal structure of S. sahachiroi AziG | 分子名称: | Azi13, SULFATE ION | 著者 | Erb, M.S, Zhang, Y, Ealick, S.E. | 登録日 | 2016-01-15 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | 主引用文献 | Polyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG. Biochemistry, 55, 2016
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3HSB
| Crystal structure of YmaH (Hfq) from Bacillus subtilis in complex with an RNA aptamer | 分子名称: | Protein hfq, RNA (5'-R(*AP*GP*AP*GP*AP*GP*A)-3') | 著者 | Baba, S, Someya, T, Kumasaka, T, Kawai, G, Nakamura, K. | 登録日 | 2009-06-10 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq Nucleic Acids Res., 40, 2012
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7N4Z
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7N53
| Complex structure of PAP4 with papaverine | 分子名称: | 1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXYISOQUINOLINE, GLYCEROL, PAP4, ... | 著者 | Kim, W, Zhang, Y. | 登録日 | 2021-06-04 | 公開日 | 2022-06-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Using fungible biosensors to evolve improved alkaloid biosyntheses. Nat.Chem.Biol., 18, 2022
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7N54
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6VHY
| NpsA-ThdA, an artificially fused Adenylation-PCP di-domain NRPS from Klebsiella oxytoca | 分子名称: | 5'-deoxy-5'-({[(2R)-2-{[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-2-(3-hydroxyphenyl)ethyl]sulfonyl}amino)adenosine, NpsA Adenylation Domain, Non-ribosomal peptide synthetase fusion protein | 著者 | Kreitler, D.F, Gulick, A.M. | 登録日 | 2020-01-10 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic PathogenKlebsiella oxytoca. Acs Infect Dis., 6, 2020
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6TO6
| Solution structure of the modulator of repression (MOR) of the temperate bacteriophage TP901-1 from Lactococcus lactis | 分子名称: | MOR | 著者 | Rasmussen, K.K, Blackledge, M, Herrmann, T, Lo Leggio, L, Jensen, M.R. | 登録日 | 2019-12-11 | 公開日 | 2020-08-19 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage. Proc.Natl.Acad.Sci.USA, 117, 2020
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7BXG
| MavC-UBE2N-Ub complex | 分子名称: | MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N | 著者 | Gao, P, Wang, Y. | 登録日 | 2020-04-19 | 公開日 | 2020-05-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.705 Å) | 主引用文献 | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
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5U55
| Psf4 in complex with Mn2+ and (S)-2-HPP | 分子名称: | (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, (S)-2-hydroxypropylphosphonic acid epoxidase, MANGANESE (II) ION | 著者 | Chekan, J.R, Nair, S.K. | 登録日 | 2016-12-06 | 公開日 | 2017-01-04 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads. ACS Chem. Biol., 12, 2017
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5U5D
| Psf4 in complex with Mn2+ and (R)-2-HPP | 分子名称: | (S)-2-hydroxypropylphosphonic acid epoxidase, MANGANESE (II) ION, [(2R)-2-hydroxypropyl]phosphonic acid | 著者 | Chekan, J.R, Nair, S.K. | 登録日 | 2016-12-06 | 公開日 | 2017-01-04 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads. ACS Chem. Biol., 12, 2017
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5T5S
| A fragment of a human tRNA synthetase | 分子名称: | Alanine--tRNA ligase, cytoplasmic | 著者 | Sun, L, Schimmel, P. | 登録日 | 2016-08-31 | 公開日 | 2016-11-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5F7Q
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8J26
| CryoEM structure of SARS CoV-2 RBD and Aptamer complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AM032-4, AM047-6, ... | 著者 | Rahman, M.S, Jang, S.K, Lee, J.O. | 登録日 | 2023-04-14 | 公開日 | 2023-06-21 | 最終更新日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure-Guided Development of Bivalent Aptamers Blocking SARS-CoV-2 Infection. Molecules, 28, 2023
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8J1Q
| CryoEM structure of SARS CoV-2 RBD and Aptamer complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AM032-0, AM047-0, ... | 著者 | Rahman, M.S, Jang, S.K, Lee, J.O. | 登録日 | 2023-04-13 | 公開日 | 2023-06-21 | 最終更新日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure-Guided Development of Bivalent Aptamers Blocking SARS-CoV-2 Infection. Molecules, 28, 2023
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8WV8
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8WVE
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8WUY
| Crystal Structure of TR3 LBD in complex with para-positioned 3,4,5-trisubstituted benzene derivatives | 分子名称: | Nuclear receptor subfamily 4immunitygroup A member 1, ~{N}-methyl-~{N}-octyl-3,4,5-tris(oxidanyl)benzamide | 著者 | Hong, W.B, Chen, X.Q, Lin, T.W. | 登録日 | 2023-10-21 | 公開日 | 2024-01-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene. Bioorg.Chem., 144, 2024
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3Q68
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7NF9
| N-terminal C2H2 Zn-finger domain of Clamp | 分子名称: | Chromatin-linked adaptor for MSL proteins, isoform A, ZINC ION | 著者 | Mariasina, S.S, Bonchuk, A.N, Tikhonova, E.A, Efimov, S.V, Maksimenko, O.G, Georgiev, P.G, Polshakov, V.I. | 登録日 | 2021-02-05 | 公開日 | 2021-12-29 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for interaction between CLAMP and MSL2 proteins involved in the specific recruitment of the dosage compensation complex in Drosophila. Nucleic Acids Res., 50, 2022
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6VHZ
| Klebsiella oxytoca NpsA N-terminal subdomain in complex with anthranilyl-AMSN | 分子名称: | 5'-{[(benzenecarbonyl)sulfamoyl]amino}-5'-deoxyadenosine, BROMIDE ION, CHLORIDE ION, ... | 著者 | Kreitler, D.F, Gulick, A.M. | 登録日 | 2020-01-10 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic PathogenKlebsiella oxytoca. Acs Infect Dis., 6, 2020
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8XU5
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