7PW7
 
 | | Human SMG1-9 kinase complex bound to a SMG1 inhibitor | | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Langer, L.M, Conti, E. | | 登録日 | 2021-10-06 | | 公開日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
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4NIK
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5U57
 | | Psf4 in complex with Fe2+ and (S)-2-HPP | | 分子名称: | (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, (S)-2-hydroxypropylphosphonic acid epoxidase, FE (III) ION | | 著者 | Chekan, J.R, Nair, S.K. | | 登録日 | 2016-12-06 | | 公開日 | 2017-01-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads.
ACS Chem. Biol., 12, 2017
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7R6K
 | | State E2 nucleolar 60S ribosomal intermediate - Model for Noc2/Noc3 region | | 分子名称: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | 登録日 | 2021-06-22 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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7PNE
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4O2H
 | | Crystal structure of BCAM1869 protein (RsaM homolog) from Burkholderia cenocepacia | | 分子名称: | protein BCAM1869 | | 著者 | Michalska, K, Chhor, G, Clancy, S, Winans, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2013-12-17 | | 公開日 | 2014-01-22 | | 最終更新日 | 2014-10-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | RsaM: a transcriptional regulator of Burkholderia spp. with novel fold.
Febs J., 281, 2014
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4NH1
 | | Crystal structure of a heterotetrameric CK2 holoenzyme complex carrying the Andante-mutation in CK2beta and consistent with proposed models of autoinhibition and trans-autophosphorylation | | 分子名称: | Casein kinase II subunit alpha, Casein kinase II subunit beta, GLYCEROL, ... | | 著者 | Schnitzler, A, Issinger, O.-G, Niefind, K. | | 登録日 | 2013-11-04 | | 公開日 | 2014-03-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The Protein Kinase CK2(Andante) Holoenzyme Structure Supports Proposed Models of Autoregulation and Trans-Autophosphorylation
J.Mol.Biol., 426, 2014
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6VHT
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3I56
 | | Co-crystal structure of Triacetyloleandomcyin Bound to the Large Ribosomal Subunit | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... | | 著者 | Gurel, G, Blaha, G, Steitz, T.A, Moore, P.B. | | 登録日 | 2009-07-03 | | 公開日 | 2010-03-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui.
Antimicrob.Agents Chemother., 53, 2009
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6VHW
 | | Klebsiella oxytoca NpsA N-terminal subdomain in complex with 3-hydroxybenzoyl-AMSN | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-deoxy-5'-{[(3-hydroxybenzene-1-carbonyl)sulfamoyl]amino}adenosine, BROMIDE ION, ... | | 著者 | Kreitler, D.F, Gulick, A.M. | | 登録日 | 2020-01-10 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic PathogenKlebsiella oxytoca.
Acs Infect Dis., 6, 2020
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5TC2
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8VRD
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5T76
 | | A fragment of a human tRNA synthetase | | 分子名称: | Alanine--tRNA ligase, cytoplasmic | | 著者 | Sun, L, Schimmel, P. | | 登録日 | 2016-09-02 | | 公開日 | 2016-11-30 | | 最終更新日 | 2017-01-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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8VRK
 | | Rigid body fitted model for refined density map of gamma tubulin ring complex capped microtubule | | 分子名称: | Actin, cytoplasmic 1, Gamma-tubulin complex component 3, ... | | 著者 | Aher, A, Urnavicius, L, Kapoor, T.M. | | 登録日 | 2024-01-22 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | | 主引用文献 | Structure of the gamma-tubulin ring complex-capped microtubule.
Nat.Struct.Mol.Biol., 31, 2024
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2J11
 | | p53 tetramerization domain mutant Y327S T329G Q331G | | 分子名称: | CELLULAR TUMOR ANTIGEN P53 | | 著者 | Carbajo, R.J, Mora, P, Sanchez del Pino, M.M, Perez-Paya, E, Pineda-Lucena, A. | | 登録日 | 2006-08-08 | | 公開日 | 2007-08-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solvent-exposed residues located in the beta-sheet modulate the stability of the tetramerization domain of p53--a structural and combinatorial approach.
Proteins, 71, 2008
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6VHU
 | | Klebsiella oxytoca NpsA N-terminal subdomain in space group P21 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BROMIDE ION, CHLORIDE ION, ... | | 著者 | Kreitler, D.F, Gulick, A.M. | | 登録日 | 2020-01-10 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic PathogenKlebsiella oxytoca.
Acs Infect Dis., 6, 2020
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3FM5
 | | X-ray crystal structure of transcriptional regulator (MarR family) from Rhodococcus sp. RHA1 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Nocek, B, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-12-19 | | 公開日 | 2009-02-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray crystal structure of transcriptional regulator (MarR family) from Rhodococcus sp. RHA1
To be Published
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3Q35
 | | Structure of the Rtt109-AcCoA/Vps75 complex and implications for chaperone-mediated histone acetylation | | 分子名称: | 1,2-ETHANEDIOL, ACETYL COENZYME *A, Histone acetyltransferase, ... | | 著者 | Tang, Y, Yuan, H, Meeth, K, Marmorstein, R. | | 登録日 | 2010-12-21 | | 公開日 | 2011-02-02 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation.
Structure, 19, 2011
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2PN0
 | | Prokaryotic transcription elongation factor GreA/GreB from Nitrosomonas europaea | | 分子名称: | Prokaryotic transcription elongation factor GreA/GreB | | 著者 | Osipiuk, J, Evdokimova, E, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-04-23 | | 公開日 | 2007-05-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of prokaryotic transcription elongation factor GreA/GreB from Nitrosomonas europaea.
To be Published
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5HMC
 | | Crystal structure of S. sahachiroi AziG complexed with 5-methyl naphthoic acid | | 分子名称: | 5-methylnaphthalene-1-carboxylic acid, Azi13, SULFATE ION | | 著者 | Zhang, Y, Erb, M.S, Ealick, S.E. | | 登録日 | 2016-01-15 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Polyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG.
Biochemistry, 55, 2016
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6VHV
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5HZR
 | | Crystal structure of MtSnf2 | | 分子名称: | 3-(1-methylpiperidinium-1-yl)propane-1-sulfonate, SNF2-family ATP dependent chromatin remodeling factor like protein, SODIUM ION, ... | | 著者 | Chen, Z.C, Xia, X. | | 登録日 | 2016-02-02 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Structure of chromatin remodeler Swi2/Snf2 in the resting state
Nat.Struct.Mol.Biol., 23, 2016
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3H6Z
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6VHX
 | | Klebsiella oxytoca NpsA N-terminal subdomain in complex with 3-hydroxyanthranilyl-AMSN | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-{[(2-amino-3-hydroxybenzene-1-carbonyl)sulfamoyl]amino}-5'-deoxyadenosine, BROMIDE ION, ... | | 著者 | Kreitler, D.F, Gulick, A.M. | | 登録日 | 2020-01-10 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic PathogenKlebsiella oxytoca.
Acs Infect Dis., 6, 2020
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6VO5
 | | Crystal structure of Human histone acetytransferas 1 (HAT1) in complex with isobutryl-COA and K12A mutant variant of histone H4 | | 分子名称: | ACETATE ION, GLYCEROL, Histone H4, ... | | 著者 | Halabelian, L, Zeng, H, Dong, A, Loppnau, P, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2020-01-30 | | 公開日 | 2020-03-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of Human histone acetytransferas 1 (HAT1) in complex with isobutryl-COA and K12A mutant variant of histone H4
to be published
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