6VHV
Klebsiella oxytoca NpsA in complex with 3-hydroxyanthranilyl-AMSN
Summary for 6VHV
Entry DOI | 10.2210/pdb6vhv/pdb |
Descriptor | NpsA Adenylation Domain, 5'-{[(2-amino-3-hydroxybenzene-1-carbonyl)sulfamoyl]amino}-5'-deoxyadenosine (3 entities in total) |
Functional Keywords | adenylation, tilivalline, tilimycin, nrps, nonribosomal peptide synthetase, biosynthetic protein |
Biological source | Klebsiella oxytoca |
Total number of polymer chains | 1 |
Total formula weight | 56035.30 |
Authors | Kreitler, D.F.,Gulick, A.M. (deposition date: 2020-01-10, release date: 2020-06-24, Last modification date: 2023-10-11) |
Primary citation | Alexander, E.M.,Kreitler, D.F.,Guidolin, V.,Hurben, A.K.,Drake, E.,Villalta, P.W.,Balbo, S.,Gulick, A.M.,Aldrich, C.C. Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic PathogenKlebsiella oxytoca. Acs Infect Dis., 6:1976-1997, 2020 Cited by PubMed: 32485104DOI: 10.1021/acsinfecdis.0c00326 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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