8TU1
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8TU0
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8TTZ
| Crystal structure of monkey TLR7 ectodomain with compound 20 | 分子名称: | (3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Critton, D.A. | 登録日 | 2023-08-15 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology. Acs Med.Chem.Lett., 15, 2024
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8TTY
| Crystal structure of monkey TLR7 ectodomain with compound 5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N~7~-butyl-2-({4-[(cyclobutylamino)methyl]-2-methoxyphenyl}methyl)-2H-pyrazolo[4,3-d]pyrimidine-5,7-diamine, ... | 著者 | Critton, D.A. | 登録日 | 2023-08-15 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology. Acs Med.Chem.Lett., 15, 2024
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8TTW
| Cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with temsavir, 8ANC195, and 10-1074 | 分子名称: | 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Tolbert, W.D, Pozharski, E, Pazgier, M. | 登録日 | 2023-08-15 | 公開日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
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8TTP
| Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, Beta-lactamase, ... | 著者 | Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2023-08-14 | 公開日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam to be published
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8TTO
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8TTN
| PHF1-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S396E, S400E, T403E, S404E) | 分子名称: | Microtubule-associated protein tau | 著者 | El Mammeri, N, Dregni, A.J, Duan, P, Hong, M. | 登録日 | 2023-08-14 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TTM
| IgG1 Fc Heterodimer combYSelect1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain | 著者 | Azzam, T, Du, J.J, Sundberg, E.J. | 登録日 | 2023-08-14 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers. Sci Adv, 10, 2024
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8TTL
| AT8-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S202E, T205E, S208E) | 分子名称: | Microtubule-associated protein tau | 著者 | El Mammeri, N, Dregni, A.J, Duan, P, Hong, M. | 登録日 | 2023-08-14 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TTK
| Tryptophan-6-halogenase BorH apo structure | 分子名称: | SULFATE ION, Tryptophan 6-halogenase | 著者 | Lingkon, K, Bellizzi, J.J. | 登録日 | 2023-08-14 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystallographic and thermodynamic evidence of negative cooperativity of flavin and tryptophan binding in the flavin-dependent halogenases AbeH and BorH. Biorxiv, 2023
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8TTJ
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8TTI
| Trp-6-Halogenase BorH complexed with FAD and Trp | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TRYPTOPHAN, ... | 著者 | Lingkon, K, Bellizzi, J.J. | 登録日 | 2023-08-14 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystallographic and thermodynamic evidence of negative cooperativity of flavin and tryptophan binding in the flavin-dependent halogenases AbeH and BorH. Biorxiv, 2023
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8TTH
| NorA single mutant - D307N at pH 7.5 | 分子名称: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | 登録日 | 2023-08-13 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | NorA single mutant - D307N at pH 7.5 To Be Published
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8TTG
| NorA single mutant - E222Q at pH 7.5 | 分子名称: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | 登録日 | 2023-08-13 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | NorA single mutant - E222Q at pH 7.5 To Be Published
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8TTF
| NorA double mutant - E222QD307N at pH 7.5 | 分子名称: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | 登録日 | 2023-08-13 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | NorA double mutant - E222QD307N at pH 7.5 To Be Published
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8TTE
| Protonated state of NorA at pH 5.0 | 分子名称: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | 登録日 | 2023-08-13 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Protonated state of NorA at pH 5.0 To Be Published
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8TTB
| Cryo-EM structure of the PP2A:B55-ARPP19 complex | 分子名称: | FE (III) ION, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | 著者 | Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. | 登録日 | 2023-08-13 | 公開日 | 2023-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
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8TT7
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8TT5
| Pseudomonas fluorescens isocyanide hydratase pH=8.3 | 分子名称: | 1,2-ETHANEDIOL, Isonitrile hydratase InhA | 著者 | Wilson, M.A, Smith, N, Dasgupta, M, Dolamore, C. | 登録日 | 2023-08-12 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | 主引用文献 | Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography. Biorxiv, 2023
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8TT4
| Pseudomonas fluorescens isocyanide hydratase pH=6.0 | 分子名称: | 1,2-ETHANEDIOL, Isonitrile hydratase InhA | 著者 | Wilson, M.A, Smith, N, Dasgupta, M, Dolamore, C. | 登録日 | 2023-08-12 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography. Biorxiv, 2023
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8TT3
| S. thermodepolymerans KpsM-KpsE in Glycolipid 2 state with rigid body fitted KpsT | 分子名称: | (2R,5S,8S)-2,5-dihydroxy-5,10-dioxo-8-[(undecanoyloxy)methyl]-4,6,9-trioxa-5lambda~5~-phosphahenicosan-1-yl 3-deoxy-alpha-L-altro-oct-2-ulopyranosidonic acid, ABC transporter ATP-binding protein, Capsular biosynthesis protein, ... | 著者 | Kuklewicz, J, Zimmer, J. | 登録日 | 2023-08-12 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular insights into capsular polysaccharide secretion. Nature, 628, 2024
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8TT2
| Pseudomonas fluorescens isocyanide hydratase pH=5.4 | 分子名称: | 1,2-ETHANEDIOL, Isonitrile hydratase InhA | 著者 | Wilson, M.A, Smith, N, Dasgupta, M, Dolamore, C. | 登録日 | 2023-08-12 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography. Biorxiv, 2023
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8TT1
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8TT0
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