PDB: 98172 件ウェブページステータス検索Chemie searchBIRD

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7MH3	Crystal structure of R. sphaeroides Photosynthetic Reaction Center variant; Y(M210)3-chlorotyrosine 分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... 著者 Mathews, I, Weaver, J.B, Boxer, S.G. 登録日 2021-04-14 公開日 2021-12-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Photosynthetic reaction center variants made via genetic code expansion show Tyr at M210 tunes the initial electron transfer mechanism. Proc.Natl.Acad.Sci.USA, 118, 2021
3BC3	Exploring inhibitor binding at the S subsites of cathepsin L 分子名称: Cathepsin L heavy and light chains, S-benzyl-N-(biphenyl-4-ylacetyl)-L-cysteinyl-N~5~-(diaminomethyl)-D-ornithyl-N-(2-phenylethyl)-L-tyrosinamide 著者 Chowdhury, S.F, Joseph, L, Kumar, S, Tulsidas, S.R, Bhat, S, Ziomek, E, Nard, R.M, Sivaraman, J, Purisima, E.O. 登録日 2007-11-12 公開日 2008-03-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Exploring inhibitor binding at the S' subsites of cathepsin L J.Med.Chem., 51, 2008
3BEX	Type III pantothenate kinase from Thermotoga maritima complexed with pantothenate 分子名称: PANTOTHENOIC ACID, PHOSPHATE ION, Type III pantothenate kinase 著者 Yang, K, Huerta, C, Strauss, E, Zhang, H. 登録日 2007-11-20 公開日 2008-06-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase. Biochemistry, 47, 2008
2E7A	TNF Receptor Subtype One-selective TNF Mutant with Antagonistic Activity 分子名称: Tumor necrosis factor 著者 Mukai, Y, Yamagata, Y, Tsutsumi, Y. 登録日 2007-01-09 公開日 2007-11-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist J.Biol.Chem., 283, 2008
8V5E	IpaD (122-321) Pi-helix Mutant (delta Q148) Bound to Deoxycholate 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCEROL, Invasin IpaD 著者 Barker, S.A, Dickenson, N.E, Johnson, S.J. 登録日 2023-11-30 公開日 2024-08-21 最終更新日 2024-09-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and functional characterization of the IpaD pi-helix reveals critical roles in DOC interaction, T3SS apparatus maturation, and Shigella virulence. J.Biol.Chem., 300, 2024
3BET	Crystal structure of the human carbonic anhydrase II in complex with STX 641 at 1.85 angstroms resolution 分子名称: (17beta)-17-(cyanomethyl)-2-methoxyestra-1(10),2,4-trien-3-yl sulfamate, Carbonic anhydrase 2, GLYCEROL, ... 著者 Di Fiore, A, De Simone, G. 登録日 2007-11-20 公開日 2008-10-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents J.Med.Chem., 51, 2008
7ML4	RNA polymerase II initially transcribing complex (ITC) 分子名称: BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. 登録日 2021-04-27 公開日 2022-02-02 最終更新日 2022-03-09 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
4MFK	The crystal structure of acyltransferase in complex with decanoyl-CoA 分子名称: Putative uncharacterized protein tcp24, SULFATE ION, decanoyl-CoA 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
5MBL	Cathepsin B in complex with DARPin 81 分子名称: Cathepsin B, DARPin 81, SULFATE ION 著者 Turk, D, Kramer, L, Renko, M, Turk, B. 登録日 2016-11-08 公開日 2017-12-20 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Cathepsin B in complex with DARPin 81 To Be Published
3B1N	Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with ADP-mizoribine 分子名称: 5-hydroxy-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... 著者 Yasutake, Y, Ota, H, Hino, E, Sakasegawa, S, Tamura, T. 登録日 2011-07-05 公開日 2011-11-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity Acta Crystallogr.,Sect.D, 67, 2011
3S9T	Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-5-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-chloro-5-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-02 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3BBR	Crystal structure of the iGluR2 ligand binding core (S1S2J-N775S) in complex with a dimeric positive modulator as well as glutamate at 2.25 A resolution 分子名称: CHLORIDE ION, GLUTAMIC ACID, GLYCEROL, ... 著者 Kastrup, J.S, Gajhede, M. 登録日 2007-11-11 公開日 2007-12-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites Chem.Biol., 14, 2007
7XSE	RNA polymerase II elongation complex transcribing a nucleosome (EC42) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-13 公開日 2022-09-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
7XTD	RNA polymerase II elongation complex transcribing a nucleosome (EC58oct) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-16 公開日 2022-09-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
7XSX	RNA polymerase II elongation complex transcribing a nucleosome (EC49) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-15 公開日 2022-09-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
8RUY	Structure of IFTA and IFTB in Retrograde Intraflagellar transport trains 分子名称: Clusterin-associated protein 1, IFT54, IFT70, ... 著者 Lacey, S, Pigino, G. 登録日 2024-01-31 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (15.4 Å) 主引用文献 Retrograde intraflagellar transport trains are a unique polymeric arrangement of IFT complexes To Be Published
7XSZ	RNA polymerase II elongation complex transcribing a nucleosome (EC115) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-15 公開日 2022-09-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
4M2W	Genetically engineered Carbonic Anhydrase IX in complex with Dorzolamide 分子名称: (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, Carbonic anhydrase 2, ZINC ION 著者 Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, McKenna, R. 登録日 2013-08-05 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.658 Å) 主引用文献 Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases. Bioorg.Med.Chem., 21, 2013
4MB2	Crystal structure of TON1374 in complex with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphopantothenate synthetase 著者 Kim, M.-K, An, Y.J, Cha, S.-S. 登録日 2013-08-19 公開日 2014-08-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 The crystal structure of a novel phosphopantothenate synthetase from the hyperthermophilic archaea, Thermococcus onnurineus NA1 Biochem.Biophys.Res.Commun., 439, 2013
3BF1	Type III pantothenate kinase from Thermotoga maritima complexed with pantothenate and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, PANTOTHENOIC ACID, Type III pantothenate kinase 著者 Yang, K, Huerta, C, Strauss, E, Zhang, H. 登録日 2007-11-20 公開日 2008-06-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase. Biochemistry, 47, 2008
5MJN	Three dimensional structure of human carbonic anhydrase II in complex with 5-[(4Chlorobenzyl)sulfanyl]thiophene-2-sulfonamide 分子名称: 5-[(4-chlorophenyl)methylsulfanyl]thiophene-2-sulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Leitans, J, Tars, K. 登録日 2016-12-01 公開日 2017-12-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations. Bioorg. Med. Chem., 25, 2017
3B1O	Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in ligand-free form 分子名称: Ribokinase, putative 著者 Yasutake, Y, Ota, H, Hino, E, Sakasegawa, S, Tamura, T. 登録日 2011-07-05 公開日 2011-11-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity Acta Crystallogr.,Sect.D, 67, 2011
3B23	Crystal structure of thrombin-variegin complex: Insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors 分子名称: Thrombin heavy chain, Thrombin light chain, Variegin 著者 Koh, C.Y, Kumar, S, Swaminathan, K, Kini, R.M. 登録日 2011-07-20 公開日 2011-11-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of thrombin in complex with s-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors Plos One, 6, 2011
7XT7	RNA polymerase II elongation complex transcribing a nucleosome (EC49B) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-16 公開日 2022-10-12 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
7XTI	RNA polymerase II elongation complex transcribing a nucleosome (EC58hex) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-17 公開日 2022-10-12 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022

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