8V5E

IpaD (122-321) Pi-helix Mutant (delta Q148) Bound to Deoxycholate

Summary for 8V5E

• Entry DOI: 10.2210/pdb8v5e/pdb
• Descriptor: Invasin IpaD, (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCEROL, ... (4 entities in total)
• Functional Keywords: t3ss, shigella, pi-helix, deoxycholate, cell invasion
• Biological source: Shigella flexneri
• Total number of polymer chains: 2
• Total formula weight: 44583.99

Authors

Barker, S.A.,Dickenson, N.E.,Johnson, S.J. (deposition date: 2023-11-30, release date: 2024-08-21)

• Primary citation: Barker, S.A.,Bernard, A.R.,Morales, Y.,Johnson, S.J.,Dickenson, N.E.; Structural and functional characterization of the IpaD pi-helix reveals critical roles in DOC interaction, T3SS apparatus maturation, and Shigella virulence.; J.Biol.Chem., :107613-107613, 2024; PubMed: 39079629; DOI: 10.1016/j.jbc.2024.107613

Experimental method

X-RAY DIFFRACTION (2.2 Å)